Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch
Gaubitz, Christl, Liu, Xingchen, Magrino, Joseph, Stone, Nicholas P., Landeck, Jacob, Hedglin, Mark, Kelch, Brian A.
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2020)
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PARP2 promotes Break Induced Replication-mediated telomere fragility in response to replication stress
Muoio, Daniela, Laspata, Natalie, Dannenberg, Rachel L., Curry, Caroline, Darkoa-Larbi, Simone, Hedglin, Mark, Uttam, Shikhar, Fouquerel, Elise
Published in Nature communications (02.04.2024)
Published in Nature communications (02.04.2024)
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Isolating Contributions from Intersegmental Transfer to DNA Searching by Alkyladenine DNA Glycosylase
Hedglin, Mark, Zhang, Yaru, O'Brien, Patrick J.
Published in The Journal of biological chemistry (23.08.2013)
Published in The Journal of biological chemistry (23.08.2013)
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PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments
Li, Mingjie, Sengupta, Bhaswati, Benkovic, Stephen J, Lee, Tae Hee, Hedglin, Mark
Published in Biochemistry (Easton) (15.12.2020)
Published in Biochemistry (Easton) (15.12.2020)
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Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics
Hoitsma, Nicole M, Norris, Jessica, Khoang, Thu H, Kaushik, Vikas, Chadda, Rahul, Antony, Edwin, Hedglin, Mark, Freudenthal, Bret D
Published in Nucleic acids research (21.07.2023)
Published in Nucleic acids research (21.07.2023)
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