Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease
Békés, Miklós, van der Heden van Noort, Gerbrand J., Ekkebus, Reggy, Ovaa, Huib, Huang, Tony T., Lima, Christopher D.
Published in Molecular cell (19.05.2016)
Published in Molecular cell (19.05.2016)
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In‐Plate Chemical Synthesis of Isopeptide‐Linked SUMOylated Peptide Fluorescence Polarization Reagents for High‐Throughput Screening of SENP Preferences
Huppelschoten, Yara, Mukhopadhyay, Rishov, Buchardt, Jens, Nielsen, Thomas E., Vertegaal, Alfred C. O., Ovaa, Huib, Heden van Noort, Gerbrand J.
Published in Chembiochem : a European journal of chemical biology (17.01.2023)
Published in Chembiochem : a European journal of chemical biology (17.01.2023)
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Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets
Flierman, Dennis, van der Heden van Noort, Gerbrand J., Ekkebus, Reggy, Geurink, Paul P., Mevissen, Tycho E.T., Hospenthal, Manuela K., Komander, David, Ovaa, Huib
Published in Cell chemical biology (21.04.2016)
Published in Cell chemical biology (21.04.2016)
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Total Chemical Synthesis of a Functionalized GFP Nanobody
Huppelschoten, Yara, Elhebieshy, Angela F., Hameed, Dharjath S., Sapmaz, Aysegul, Buchardt, Jens, Nielsen, Thomas E., Ovaa, Huib, Heden van Noort, Gerbrand J.
Published in Chembiochem : a European journal of chemical biology (06.10.2022)
Published in Chembiochem : a European journal of chemical biology (06.10.2022)
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Noncanonical and reversible cysteine ubiquitination prevents the overubiquitination of PEX5 at the peroxisomal membrane
Francisco, Tânia, Pedrosa, Ana G, Rodrigues, Tony A, Abalkhail, Tarad, Li, Hongli, Ferreira, Maria J, van der Heden van Noort, Gerbrand J, Fransen, Marc, Hettema, Ewald H, Azevedo, Jorge E
Published in PLoS biology (01.03.2024)
Published in PLoS biology (01.03.2024)
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Generation of the UFM1 Toolkit for Profiling UFM1‐Specific Proteases and Ligases
Witting, Katharina F., van der Heden van Noort, Gerbrand J., Kofoed, Christian, Talavera Ormeño, Cami, el Atmioui, Dris, Mulder, Monique P. C., Ovaa, Huib
Published in Angewandte Chemie International Edition (22.10.2018)
Published in Angewandte Chemie International Edition (22.10.2018)
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Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Proteasome System
Janssen, Guido V., Zhang, Susan, Merkx, Remco, Schiesswohl, Christa, Chatterjee, Champak, Darwin, K. Heran, Geurink, Paul P., Heden van Noort, Gerbrand J., Ovaa, Huib
Published in Chembiochem : a European journal of chemical biology (03.11.2021)
Published in Chembiochem : a European journal of chemical biology (03.11.2021)
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Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo
van Huizen, Mariska, Bloeme-Ter Horst, Jonna R, de Gruyter, Heidi L M, Geurink, Paul P, van der Heden van Noort, Gerbrand J, Knaap, Robert C M, Nelemans, Tessa, Ogando, Natacha S, Leijs, Anouk A, Urakova, Nadya, Mark, Brian L, Snijder, Eric J, Myeni, Sebenzile K, Kikkert, Marjolein
Published in PLoS pathogens (01.03.2024)
Published in PLoS pathogens (01.03.2024)
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Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
Klemm, Theresa, Ebert, Gregor, Calleja, Dale J, Allison, Cody C, Richardson, Lachlan W, Bernardini, Jonathan P, Lu, Bernadine GC, Kuchel, Nathan W, Grohmann, Christoph, Shibata, Yuri, Gan, Zhong Yan, Cooney, James P, Doerflinger, Marcel, Au, Amanda E, Blackmore, Timothy R, van der Heden van Noort, Gerbrand J, Geurink, Paul P, Ovaa, Huib, Newman, Janet, Riboldi‐Tunnicliffe, Alan, Czabotar, Peter E, Mitchell, Jeffrey P, Feltham, Rebecca, Lechtenberg, Bernhard C, Lowes, Kym N, Dewson, Grant, Pellegrini, Marc, Lessene, Guillaume, Komander, David
Published in The EMBO journal (15.09.2020)
Published in The EMBO journal (15.09.2020)
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Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection
Mukherjee, Rukmini, Bhattacharya, Anshu, Bojkova, Denisa, Mehdipour, Ahmad Reza, Shin, Donghyuk, Khan, Khadija Shahed, Hei-Yin Cheung, Hayley, Wong, Kam-Bo, Ng, Wai-Lung, Cinatl, Jindrich, Geurink, Paul P., van der Heden van Noort, Gerbrand J., Rajalingam, Krishnaraj, Ciesek, Sandra, Hummer, Gerhard, Dikic, Ivan
Published in The Journal of biological chemistry (01.08.2021)
Published in The Journal of biological chemistry (01.08.2021)
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RNA virus hijacks an incognito function of a DNA repair enzyme
Virgen-Slane, Richard, Rozovics, Janet M, Fitzgerald, Kerry D, Ngo, Tuan, Chou, Wayne, van der Heden van Noort, Gerbrand J, Filippov, Dmitri V, Gershon, Paul D, Semler, Bert L
Published in Proceedings of the National Academy of Sciences - PNAS (04.09.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (04.09.2012)
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Stereoselective Ribosylation of Amino Acids
Kistemaker, Hans A. V, van der Heden van Noort, Gerbrand J, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V
Published in Organic letters (03.05.2013)
Published in Organic letters (03.05.2013)
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Total Chemical Synthesis of LC3A and LC3B Activity-Based Probes
Huppelschoten, Yara, Buchardt, Jens, Nielsen, Thomas E, Sapmaz, Aysegul, van der Heden van Noort, Gerbrand J
Published in Biomedicines (01.03.2023)
Published in Biomedicines (01.03.2023)
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Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection
Shin, Donghyuk, Bhattacharya, Anshu, Cheng, Yi-Lin, Alonso, Marta Campos, Mehdipour, Ahmad Reza, van der Heden van Noort, Gerbrand J, Ovaa, Huib, Hummer, Gerhard, Dikic, Ivan
Published in eLife (13.11.2020)
Published in eLife (13.11.2020)
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Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection
Kim, Robbert Q., Misra, Mohit, Gonzalez, Alexis, Tomašković, Ines, Shin, Donghyuk, Schindelin, Hermann, Filippov, Dmitri V., Ovaa, Huib, Đikić, Ivan, Heden van Noort, Gerbrand J.
Published in Chemistry : a European journal (01.02.2021)
Published in Chemistry : a European journal (01.02.2021)
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A General Approach Towards Triazole‐Linked Adenosine Diphosphate Ribosylated Peptides and Proteins
Liu, Qiang, Kistemaker, Hans A. V., Bhogaraju, Sagar, Dikic, Ivan, Overkleeft, Herman S., van der Marel, Gijsbert A., Ovaa, Huib, van der Heden van Noort, Gerbrand J., Filippov, Dmitri V.
Published in Angewandte Chemie International Edition (05.02.2018)
Published in Angewandte Chemie International Edition (05.02.2018)
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Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC
Madern, Jerre M., Kim, Robbert Q., Misra, Mohit, Dikic, Ivan, Zhang, Yong, Ovaa, Huib, Codée, Jeroen D. C., Filippov, Dmitri V., Heden van Noort, Gerbrand J.
Published in Chembiochem : a European journal of chemical biology (15.10.2020)
Published in Chembiochem : a European journal of chemical biology (15.10.2020)
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Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
Shin, Donghyuk, Mukherjee, Rukmini, Grewe, Diana, Bojkova, Denisa, Baek, Kheewoong, Bhattacharya, Anshu, Schulz, Laura, Widera, Marek, Mehdipour, Ahmad Reza, Tascher, Georg, Geurink, Paul P., Wilhelm, Alexander, van der Heden van Noort, Gerbrand J., Ovaa, Huib, Müller, Stefan, Knobeloch, Klaus-Peter, Rajalingam, Krishnaraj, Schulman, Brenda A., Cinatl, Jindrich, Hummer, Gerhard, Ciesek, Sandra, Dikic, Ivan
Published in Nature (London) (26.11.2020)
Published in Nature (London) (26.11.2020)
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