End Points, Collection, Processing, and Time: Four Key Elements to Consider When Planning for Use of Handheld Devices in a Drug Development Setting
Pradhan, Vivek, Heatherington, Anne C., Bhattacharya, Indranil
Published in Clinical pharmacology and therapeutics (01.04.2020)
Published in Clinical pharmacology and therapeutics (01.04.2020)
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Journal Article
Passage of erythropoietic agents across the blood–brain barrier: a comparison of human and murine erythropoietin and the analog darbepoetin alfa
Banks, William A., Jumbe, Nelson L., Farrell, Catherine L., Niehoff, Michael L., Heatherington, Anne C.
Published in European journal of pharmacology (28.11.2004)
Published in European journal of pharmacology (28.11.2004)
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Journal Article
Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy
Agoram, Balaji, Heatherington, Anne C, Gastonguay, Marc R
Published in The AAPS journal (01.09.2006)
Published in The AAPS journal (01.09.2006)
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Journal Article
Lymphatic Absorption Is the Primary Contributor to the Systemic Availability of Epoetin Alfa following Subcutaneous Administration to Sheep
McLennan, Danielle N, Porter, Christopher J H, Edwards, Glenn A, Martin, Steven W, Heatherington, Anne C, Charman, Susan A
Published in The Journal of pharmacology and experimental therapeutics (01.04.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2005)
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Journal Article
Pharmacokinetics and pharmacodynamics of darbepoetin alfa and epoetin in patients undergoing dialysis
Allon, Michael, Kleinman, Kenneth, Walczyk, Michael, Kaupke, Charles, Messer-Mann, Louise, Olson, Kurt, Heatherington, Anne C, Maroni, Bradley J
Published in Clinical pharmacology and therapeutics (01.11.2002)
Published in Clinical pharmacology and therapeutics (01.11.2002)
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Journal Article
The absorption of darbepoetin alfa occurs predominantly via the lymphatics following subcutaneous administration to sheep
MCLENNAN, Danielle N, PORTER, Christopher J. H, EDWARDS, Glenn A, HEATHERINGTON, Anne C, MARTIN, Steven W, CHARMAN, Susan A
Published in Pharmaceutical research (01.09.2006)
Published in Pharmaceutical research (01.09.2006)
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Journal Article
Development and validation of a quantitative cell-based bioassay for comparing the pharmacokinetic profiles of two recombinant erythropoietic proteins in serum
Wei, Xin, Grill, Diana S., Heatherington, Anne C., Swanson, Steven J., Gupta, Shalini
Published in Journal of pharmaceutical and biomedical analysis (17.01.2007)
Published in Journal of pharmaceutical and biomedical analysis (17.01.2007)
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Journal Article
Pharmacokinetics of darbepoetin alfa after intravenous or subcutaneous administration in patients with non-myeloid malignancies undergoing chemotherapy
HEATHERINGTON, Anne C, DITTRICH, Christian, SULLIVAN, John T, ROSSI, Greg, SCHUELLER, Johannes
Published in Clinical pharmacokinetics (01.01.2006)
Published in Clinical pharmacokinetics (01.01.2006)
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Journal Article
Kinetics of haematopoietic recovery after dose‐intensive chemo/radiotherapy in mice: optimized erythroid support with darbepoetin alpha
Hartley, Cynthia, Elliott, Steve, Begley, C. Glenn, McElroy, Patricia, Sutherland, Weston, Khaja, Raheem, Heatherington, Anne C., Graves, Tom, Schultz, Henry, Del Castillo, Juan, Molineux, Graham
Published in British journal of haematology (01.08.2003)
Published in British journal of haematology (01.08.2003)
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Journal Article
Application of Quantitative Pharmacology Approaches in Bridging Pharmacokinetics and Pharmacodynamics of Domagrozumab From Adult Healthy Subjects to Pediatric Patients With Duchenne Muscular Disease
Bhattacharya, Indranil, Manukyan, Zorayr, Chan, Phylinda, Heatherington, Anne, Harnisch, Lutz
Published in Journal of clinical pharmacology (01.03.2018)
Published in Journal of clinical pharmacology (01.03.2018)
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Journal Article
Applying the best of oncology drug development paradigms to the non-malignant space
Bhattacharya, Indranil, Heatherington, Anne, Barton, Jeremy
Published in Drug discovery today (01.12.2016)
Published in Drug discovery today (01.12.2016)
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Journal Article
A Quantitative Systems Pharmacology Model for the Coagulation Network Describes Biomarker Changes Observed in a Clinical Study with FXa Variant and Predicts Age-Associated Biomarker Variations
Nayak, Satyaprakash, Lee, Dooyoung, Arkin, Steven, Martin, Steven W., Heatherington, Anne C., Denney, William S., Vicini, Paolo, Hua, Fei
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
A Systems Biology Model for the Coagulation Network in Non-Bleeding State Describes Baseline Activity of Coagulation
Lee, Dooyoung, Nayak, Satyaprakash, Pittman, Debra, Arkin, Steven, Martin, Steven, Heatherington, Anne C, Vicini, Paolo, Hua, Fei
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
A physiologically based pharmacokinetic model incorporating dispersion principles to describe solute distribution in the perfused rat hindlimb preparation
OLIVER, R. E, HEATHERINGTON, A. C, JONES, A. F, ROWLAND, M
Published in Journal of pharmacokinetics and biopharmaceutics (01.08.1997)
Published in Journal of pharmacokinetics and biopharmaceutics (01.08.1997)
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