A noncanonical AR addiction drives enzalutamide resistance in prostate cancer
He, Yundong, Wei, Ting, Ye, Zhenqing, Orme, Jacob J., Lin, Dong, Sheng, Haoyue, Fazli, Ladan, Jeffrey Karnes, R., Jimenez, Rafael, Wang, Liguo, Wang, Liewei, Gleave, Martin E., Wang, Yuzhuo, Shi, Lei, Huang, Haojie
Published in Nature communications (09.03.2021)
Published in Nature communications (09.03.2021)
Get full text
Journal Article
Aberrant activation of super enhancer and choline metabolism drive antiandrogen therapy resistance in prostate cancer
Wen, Simeng, He, Yundong, Wang, Liewei, Zhang, Jun, Quan, Changyi, Niu, Yuanjie, Huang, Haojie
Published in Oncogene (15.10.2020)
Published in Oncogene (15.10.2020)
Get full text
Journal Article
Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation
Zhang, Pingzhao, Wang, Dejie, Zhao, Yu, Ren, Shancheng, Gao, Kun, Ye, Zhenqing, Wang, Shangqian, Pan, Chun-Wu, Zhu, Yasheng, Yan, Yuqian, Yang, Yinhui, Wu, Di, He, Yundong, Zhang, Jun, Lu, Daru, Liu, Xiuping, Yu, Long, Zhao, Shimin, Li, Yao, Lin, Dong, Wang, Yuzhuo, Wang, Liguo, Chen, Yu, Sun, Yinghao, Wang, Chenji, Huang, Haojie
Published in Nature medicine (01.09.2017)
Published in Nature medicine (01.09.2017)
Get full text
Journal Article
PTEN Loss Promotes Intratumoral Androgen Synthesis and Tumor Microenvironment Remodeling via Aberrant Activation of RUNX2 in Castration-Resistant Prostate Cancer
Yang, Yinhui, Bai, Yang, He, Yundong, Zhao, Yu, Chen, Jiaxiang, Ma, Linlin, Pan, Yunqian, Hinten, Michael, Zhang, Jun, Karnes, R Jeffrey, Kohli, Manish, Westendorf, Jennifer J, Li, Benyi, Zhu, Runzhi, Huang, Haojie, Xu, Wanhai
Published in Clinical cancer research (15.02.2018)
Published in Clinical cancer research (15.02.2018)
Get full text
Journal Article
SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition
Ma, Jian, Shi, Qing, Cui, Gaofeng, Sheng, Haoyue, Botuyan, Maria Victoria, Zhou, Yingke, Yan, Yuqian, He, Yundong, Wang, Liguo, Wang, Yuzhuo, Mer, Georges, Ye, Dingwei, Wang, Chenji, Huang, Haojie
Published in Nature communications (01.10.2021)
Published in Nature communications (01.10.2021)
Get full text
Journal Article
Androgen receptor splice variants bind to constitutively open chromatin and promote abiraterone-resistant growth of prostate cancer
He, Yundong, Lu, Ji, Ye, Zhenqing, Hao, Siyuan, Wang, Liewei, Kohli, Manish, Tindall, Donald J, Li, Benyi, Zhu, Runzhi, Wang, Liguo, Huang, Haojie
Published in Nucleic acids research (28.02.2018)
Published in Nucleic acids research (28.02.2018)
Get full text
Journal Article
Targeting signaling pathways in prostate cancer: mechanisms and clinical trials
He, Yundong, Xu, Weidong, Xiao, Yu-Tian, Huang, Haojie, Gu, Di, Ren, Shancheng
Published in Signal transduction and targeted therapy (24.06.2022)
Published in Signal transduction and targeted therapy (24.06.2022)
Get full text
Journal Article
Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer
He, Yundong, Peng, Shihong, Wang, Jinhua, Chen, Huang, Cong, Xiaonan, Chen, Ang, Hu, Meichun, Qin, Min, Wu, Haigang, Gao, Shuman, Wang, Liguo, Wang, Xin, Yi, Zhengfang, Liu, Mingyao
Published in Nature communications (13.12.2016)
Published in Nature communications (13.12.2016)
Get full text
Journal Article
TMPRSS2-ERG Controls Luminal Epithelial Lineage and Antiandrogen Sensitivity in PTEN and TP53 -Mutated Prostate Cancer
Blee, Alexandra M, He, Yundong, Yang, Yinhui, Ye, Zhenqing, Yan, Yuqian, Pan, Yunqian, Ma, Tao, Dugdale, Joseph, Kuehn, Emily, Kohli, Manish, Jimenez, Rafael, Chen, Yu, Xu, Wanhai, Wang, Liguo, Huang, Haojie
Published in Clinical cancer research (15.09.2018)
Published in Clinical cancer research (15.09.2018)
Get full text
Journal Article
Advances in landscape and related therapeutic targets of the prostate tumor microenvironment
Li, Duocai, Xu, Weidong, Chang, Yifan, Xiao, Yutian, He, Yundong, Ren, Shancheng
Published in Acta biochimica et biophysica Sinica (09.06.2023)
Published in Acta biochimica et biophysica Sinica (09.06.2023)
Get full text
Journal Article
Torque Coordination Control of an Electro-Hydraulic Composite Brake System During Mode Switching Based on Braking Intention
Yang, Yang, He, Yundong, Yang, Zhong, Fu, Chunyun, Cong, Zhipeng
Published in Energies (Basel) (01.04.2020)
Published in Energies (Basel) (01.04.2020)
Get full text
Journal Article
Destruction of DNA‐Binding Proteins by Programmable Oligonucleotide PROTAC (O'PROTAC): Effective Targeting of LEF1 and ERG
Shao, Jingwei, Yan, Yuqian, Ding, Donglin, Wang, Dejie, He, Yundong, Pan, Yunqian, Yan, Wei, Kharbanda, Anupreet, Li, Hong‐yu, Huang, Haojie
Published in Advanced science (01.10.2021)
Published in Advanced science (01.10.2021)
Get full text
Journal Article
Loss of FOXO1 Cooperates with TMPRSS2-ERG Overexpression to Promote Prostate Tumorigenesis and Cell Invasion
Yang, Yinhui, Blee, Alexandra M, Wang, Dejie, An, Jian, Pan, Yunqian, Yan, Yuqian, Ma, Tao, He, Yundong, Dugdale, Joseph, Hou, Xiaonan, Zhang, Jun, Weroha, S John, Zhu, Wei-Guo, Wang, Y Alan, DePinho, Ronald A, Xu, Wanhai, Huang, Haojie
Published in Cancer research (Chicago, Ill.) (01.12.2017)
Published in Cancer research (Chicago, Ill.) (01.12.2017)
Get full text
Journal Article
Lycorine is a novel inhibitor of the growth and metastasis of hormone-refractory prostate cancer
Hu, Meichun, Peng, Shihong, He, Yundong, Qin, Min, Cong, Xiaonan, Xing, Yajing, Liu, Mingyao, Yi, Zhengfang
Published in Oncotarget (20.06.2015)
Published in Oncotarget (20.06.2015)
Get full text
Journal Article
Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): from bench to bedside
Bao, Xuhui, Liang, Yongjun, Chang, Hanman, Cai, Tianji, Feng, Baijie, Gordon, Konstantin, Zhu, Yuekun, Shi, Hailian, He, Yundong, Xie, Liyi
Published in Signal transduction and targeted therapy (08.01.2024)
Published in Signal transduction and targeted therapy (08.01.2024)
Get full text
Journal Article
A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer
Wang, Jinhua, Xing, Yajing, Wang, Yingying, He, Yundong, Wang, Liting, Peng, Shihong, Yang, Lianfang, Xie, Jiuqing, Li, Xiaotao, Qiu, Wenwei, Yi, Zhengfang, Liu, Mingyao
Published in Journal of experimental & clinical cancer research (22.10.2019)
Published in Journal of experimental & clinical cancer research (22.10.2019)
Get full text
Journal Article
Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression
Lin, Qingxiang, He, Yuan, Wang, Xue, Zhang, Yong, Hu, Meichun, Guo, Weikai, He, Yundong, Zhang, Tao, Lai, Li, Sun, Zhenliang, Yi, Zhengfang, Liu, Mingyao, Chen, Yihua
Published in Advanced science (01.05.2020)
Published in Advanced science (01.05.2020)
Get full text
Journal Article
Inhibition of EZH2 by chemo- and radiotherapy agents and small molecule inhibitors induces cell death in castration-resistant prostate cancer
Wu, Changping, Jin, Xin, Yang, Jing, Yang, Yinhui, He, Yundong, Ding, Liya, Pan, Yunqian, Chen, Shuai, Jiang, Jingting, Huang, Haojie
Published in Oncotarget (19.01.2016)
Published in Oncotarget (19.01.2016)
Get full text
Journal Article
Dual inhibition of AKT‐mTOR and AR signaling by targeting HDAC3 in PTEN‐ or SPOP‐mutated prostate cancer
Yan, Yuqian, An, Jian, Yang, Yinhui, Wu, Di, Bai, Yang, Cao, William, Ma, Linlin, Chen, Junhui, Yu, Zhendong, He, Yundong, Jin, Xin, Pan, Yunqian, Ma, Tao, Wang, Shangqian, Hou, Xiaonan, Weroha, Saravut John, Karnes, R Jeffrey, Zhang, Jun, Westendorf, Jennifer J, Wang, Liguo, Chen, Yu, Xu, Wanhai, Zhu, Runzhi, Wang, Dejie, Huang, Haojie
Published in EMBO molecular medicine (01.04.2018)
Published in EMBO molecular medicine (01.04.2018)
Get full text
Journal Article
Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 4
Guo, Mengmeng, Hu, Pan, Xie, Jiayi, Tang, Kefu, Hu, Shixiu, Sun, Jialiang, He, Yundong, Li, Jing, Lu, Weiqiang, Liu, Huirong, Liu, Mingyao, Yi, Zhengfang, Peng, Shihong
Published in Genes & diseases (01.07.2024)
Published in Genes & diseases (01.07.2024)
Get full text
Journal Article