CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age
Menon, Tejas, Illing, Patricia T., Chaurasia, Priyanka, McQuilten, Hayley A., Shepherd, Chloe, Rowntree, Louise C., Petersen, Jan, Littler, Dene R., Khuu, Grace, Huang, Ziyi, Allen, Lilith F., Rockman, Steve, Crowe, Jane, Flanagan, Katie L., Wakim, Linda M., Nguyen, Thi H. O., Mifsud, Nicole A., Rossjohn, Jamie, Purcell, Anthony W., van de Sandt, Carolien E., Kedzierska, Katherine
Published in Nature communications (29.04.2024)
Published in Nature communications (29.04.2024)
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Prior infection with unrelated neurotropic virus exacerbates influenza disease and impairs lung T cell responses
Foo, Isabelle Jia-Hui, Chua, Brendon Y., Clemens, E. Bridie, Chang, So Young, Jia, Xiaoxiao, McQuilten, Hayley A., Yap, Ashley Huey Yiing, Cabug, Aira F., Ashayeripanah, Mitra, McWilliam, Hamish E. G., Villadangos, Jose A., Evrard, Maximilien, Mackay, Laura K., Wakim, Linda M., Fazakerley, John K., Kedzierska, Katherine, Kedzierski, Lukasz
Published in Nature communications (23.03.2024)
Published in Nature communications (23.03.2024)
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Immature Brain Cortical Neurons Have Low Transcriptional Competence to Activate Antiviral Defences and Control RNA Virus Infections
Narayanan, Divya, Moily, Nagaraj, McQuilten, Hayley A., Kedzierska, Katherine, Mackenzie, Jason M., Kedzierski, Lukasz, Fazakerley, John K.
Published in Journal of innate immunity (01.01.2023)
Published in Journal of innate immunity (01.01.2023)
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Immunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques
Chua, Brendon Y, Sekiya, Toshiki, Koutsakos, Marios, Nomura, Naoki, Rowntree, Louise C, Nguyen, Thi H O, McQuilten, Hayley A, Ohno, Marumi, Ohara, Yuki, Nishimura, Tomohiro, Endo, Masafumi, Itoh, Yasushi, Habel, Jennifer R, Selva, Kevin J, Wheatley, Adam K, Wines, Bruce D, Hogarth, P Mark, Kent, Stephen J, Chung, Amy W, Jackson, David C, Brown, Lorena E, Shingai, Masashi, Kedzierska, Katherine, Kida, Hiroshi
Published in PLoS pathogens (07.10.2022)
Published in PLoS pathogens (07.10.2022)
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TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs
Deliyannis, Georgia, Wong, Chinn Yi, McQuilten, Hayley A, Bachem, Annabell, Clarke, Michele, Jia, Xiaoxiao, Horrocks, Kylie, Zeng, Weiguang, Girkin, Jason, Scott, Nichollas E, Londrigan, Sarah L, Reading, Patrick C, Bartlett, Nathan W, Kedzierska, Katherine, Brown, Lorena E, Mercuri, Francesca, Demaison, Christophe, Jackson, David C, Chua, Brendon Y
Published in JCI insight (08.03.2021)
Published in JCI insight (08.03.2021)
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CD4⁺ T help promotes influenza virus-specific CD8⁺ T cell memory by limiting metabolic dysfunction
Cullen, Jolie G., McQuilten, Hayley A., Quinn, Kylie M., Olshansky, Moshe, Russ, Brendan E., Morey, Alison, Wei, Sanna, Prier, Julia E., La Gruta, Nicole L., Doherty, Peter C., Turner, Stephen J.
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
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SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection
Rowntree, Louise C., Nguyen, Thi H.O., Kedzierski, Lukasz, Neeland, Melanie R., Petersen, Jan, Crawford, Jeremy Chase, Allen, Lilith F., Clemens, E. Bridie, Chua, Brendon, McQuilten, Hayley A., Minervina, Anastasia A., Pogorelyy, Mikhail V., Chaurasia, Priyanka, Tan, Hyon-Xhi, Wheatley, Adam K., Jia, Xiaoxiao, Amanat, Fatima, Krammer, Florian, Allen, E. Kaitlynn, Sonda, Sabrina, Flanagan, Katie L., Jumarang, Jaycee, Pannaraj, Pia S., Licciardi, Paul V., Kent, Stephen J., Bond, Katherine A., Williamson, Deborah A., Rossjohn, Jamie, Thomas, Paul G., Tosif, Shidan, Crawford, Nigel W., van de Sandt, Carolien E., Kedzierska, Katherine
Published in Immunity (12.07.2022)
Published in Immunity (12.07.2022)
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Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan
van de Sandt, Carolien E., Nguyen, Thi H. O., Gherardin, Nicholas A., Crawford, Jeremy Chase, Samir, Jerome, Minervina, Anastasia A., Pogorelyy, Mikhail V., Rizzetto, Simone, Szeto, Christopher, Kaur, Jasveen, Ranson, Nicole, Sonda, Sabrina, Harper, Alice, Redmond, Samuel J., McQuilten, Hayley A., Menon, Tejas, Sant, Sneha, Jia, Xiaoxiao, Pedrina, Kate, Karapanagiotidis, Theo, Cain, Natalie, Nicholson, Suellen, Chen, Zhenjun, Lim, Ratana, Clemens, E. Bridie, Eltahla, Auda, La Gruta, Nicole L., Crowe, Jane, Lappas, Martha, Rossjohn, Jamie, Godfrey, Dale I., Thomas, Paul G., Gras, Stephanie, Flanagan, Katie L., Luciani, Fabio, Kedzierska, Katherine
Published in Nature immunology (01.11.2023)
Published in Nature immunology (01.11.2023)
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In Semliki Forest virus encephalitis, suppressor of cytokine signaling 4 (SOCS4) is an essential modulator of immune responses that mediates the balance between immunopathology and virus clearance
Kedzierski, Lukasz, Er Qi Tan, Abigail, Jia Hui Foo, Isabelle, Narayanan, Divya, Moily, Nagaraj, McQuilten, Hayley A, Nicholson, Sandra E, Fazakerley, John K
Published in Immunology and cell biology (01.04.2023)
Published in Immunology and cell biology (01.04.2023)
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Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities
Zhang, Wuji, Kedzierski, Lukasz, Chua, Brendon Y., Mayo, Mark, Lonzi, Claire, Rigas, Vanessa, Middleton, Bianca F., McQuilten, Hayley A., Rowntree, Louise C., Allen, Lilith F., Purcell, Ruth A., Tan, Hyon-Xhi, Petersen, Jan, Chaurasia, Priyanka, Mordant, Francesca, Pogorelyy, Mikhail V., Minervina, Anastasia A., Crawford, Jeremy Chase, Perkins, Griffith B., Zhang, Eva, Gras, Stephanie, Clemens, E. Bridie, Juno, Jennifer A., Audsley, Jennifer, Khoury, David S., Holmes, Natasha E., Thevarajan, Irani, Subbarao, Kanta, Krammer, Florian, Cheng, Allen C., Davenport, Miles P., Grubor-Bauk, Branka, Coates, P. Toby, Christensen, Britt, Thomas, Paul G., Wheatley, Adam K., Kent, Stephen J., Rossjohn, Jamie, Chung, Amy W., Boffa, John, Miller, Adrian, Lynar, Sarah, Nelson, Jane, Nguyen, Thi H. O., Davies, Jane, Kedzierska, Katherine
Published in Nature immunology (01.06.2023)
Published in Nature immunology (01.06.2023)
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High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases
Jia, Xiaoxiao, Crawford, Jeremy Chase, Gebregzabher, Deborah, Monson, Ebony A., Mettelman, Robert C., Wan, Yanmin, Ren, Yanqin, Chou, Janet, Novak, Tanya, McQuilten, Hayley A., Clarke, Michele, Bachem, Annabell, Foo, Isabelle J., Fritzlar, Svenja, Carrera Montoya, Julio, Trenerry, Alice M., Nie, Shuai, Leeming, Michael G., Nguyen, Thi H.O., Kedzierski, Lukasz, Littler, Dene R., Kueh, Andrew, Cardamone, Tina, Wong, Chinn Yi, Hensen, Luca, Cabug, Aira, Laguna, Jaime Gómez, Agrawal, Mona, Flerlage, Tim, Boyd, David F., Van de Velde, Lee-Ann, Habel, Jennifer R., Loh, Liyen, Koay, Hui-Fern, van de Sandt, Carolien E., Konstantinov, Igor E., Berzins, Stuart P., Flanagan, Katie L., Wakim, Linda M., Herold, Marco J., Green, Amanda M., Smallwood, Heather S., Rossjohn, Jamie, Thwaites, Ryan S., Chiu, Christopher, Scott, Nichollas E., Mackenzie, Jason M., Bedoui, Sammy, Reading, Patrick C., Londrigan, Sarah L., Helbig, Karla J., Randolph, Adrienne G., Thomas, Paul G., Xu, Jianqing, Wang, Zhongfang, Chua, Brendon Y., Kedzierska, Katherine
Published in Cell (22.08.2024)
Published in Cell (22.08.2024)
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SARS-CoV-2-specific CD8 + T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years
Rowntree, Louise C, Audsley, Jennifer, Allen, Lilith F, McQuilten, Hayley A, Hagen, Ruth R, Chaurasia, Priyanka, Petersen, Jan, Littler, Dene R, Tan, Hyon-Xhi, Murdiyarso, Lydia, Habel, Jennifer R, Foo, Isabelle J H, Zhang, Wuji, Ten Berge, Elizabeth R V, Ganesh, Hanujah, Kaewpreedee, Prathanporn, Lee, Kelly W K, Cheng, Samuel M S, Kwok, Janette S Y, Jayasinghe, Dhilshan, Gras, Stephanie, Juno, Jennifer A, Wheatley, Adam K, Kent, Stephen J, Rossjohn, Jamie, Cheng, Allen C, Kotsimbos, Tom C, Trubiano, Jason A, Holmes, Natasha E, Pang Chan, Ken Ka, Hui, David S C, Peiris, Malik, Poon, Leo L M, Lewin, Sharon R, Doherty, Peter C, Thevarajan, Irani, Valkenburg, Sophie A, Kedzierska, Katherine, Nguyen, Thi H O
Published in Proceedings of the National Academy of Sciences - PNAS (24.09.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (24.09.2024)
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Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster
Nolan, Terry M, Deliyannis, Georgia, Griffith, Maryanne, Braat, Sabine, Allen, Lilith F, Audsley, Jennifer, Chung, Amy W, Ciula, Marcin, Gherardin, Nicholas A, Giles, Michelle L, Gordon, Tom P, Grimley, Samantha L, Horng, Lana, Jackson, David C, Juno, Jennifer A, Kedzierska, Katherine, Kent, Stephen J, Lewin, Sharon R, Littlejohn, Mason, McQuilten, Hayley A, Mordant, Francesca L, Nguyen, Thi H O, Soo, Vanessa Pac, Price, Briony, Purcell, Damian F J, Ramanathan, Pradhipa, Redmond, Samuel J, Rockman, Steven, Ruan, Zheng, Sasadeusz, Joseph, Simpson, Julie A, Subbarao, Kanta, Fabb, Stewart A, Payne, Thomas J, Takanashi, Asuka, Tan, Chee Wah, Torresi, Joseph, Wang, Jing Jing, Wang, Lin-Fa, Al-Wassiti, Hareth, Wong, Chinn Yi, Zaloumis, Sophie, Pouton, Colin W, Godfrey, Dale I
Published in EBioMedicine (01.12.2023)
Published in EBioMedicine (01.12.2023)
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Robust SARS-CoV-2 T cell responses with common TCRαβ motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cells
Nguyen, Thi H.O., Rowntree, Louise C., Allen, Lilith F., Chua, Brendon Y., Kedzierski, Lukasz, Lim, Chhay, Lasica, Masa, Tennakoon, G. Surekha, Saunders, Natalie R., Crane, Megan, Chee, Lynette, Seymour, John F., Anderson, Mary Ann, Whitechurch, Ashley, Clemens, E. Bridie, Zhang, Wuji, Chang, So Young, Habel, Jennifer R., Jia, Xiaoxiao, McQuilten, Hayley A., Minervina, Anastasia A., Pogorelyy, Mikhail V., Chaurasia, Priyanka, Petersen, Jan, Menon, Tejas, Hensen, Luca, Neil, Jessica A., Mordant, Francesca L., Tan, Hyon-Xhi, Cabug, Aira F., Wheatley, Adam K., Kent, Stephen J., Subbarao, Kanta, Karapanagiotidis, Theo, Huang, Han, Vo, Lynn K., Cain, Natalie L., Nicholson, Suellen, Krammer, Florian, Gibney, Grace, James, Fiona, Trevillyan, Janine M., Trubiano, Jason A., Mitchell, Jeni, Christensen, Britt, Bond, Katherine A., Williamson, Deborah A., Rossjohn, Jamie, Crawford, Jeremy Chase, Thomas, Paul G., Thursky, Karin A., Slavin, Monica A., Tam, Constantine S., Teh, Benjamin W., Kedzierska, Katherine
Published in Cell reports. Medicine (18.04.2023)
Published in Cell reports. Medicine (18.04.2023)
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Evaluation of Intranasal TLR2/6 agonist INNA-051: Safety, Tolerability and Proof of Pharmacology
Mercuri, Francesca A., White, Scott, McQuilten, Hayley A, Lemech, Charlotte, Mynhardt, Stephan, Hari, Rana, Zhang, Ping, Kruger, Nicole, McLachlan, Grant, Miller, Bruce E., West, Nicholas P., Tal-Singer, Ruth, Demaison, Christophe
Published in ERJ open research (13.06.2024)
Published in ERJ open research (13.06.2024)
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Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose boosterResearch in context
Terry M. Nolan, Georgia Deliyannis, Maryanne Griffith, Sabine Braat, Lilith F. Allen, Jennifer Audsley, Amy W. Chung, Marcin Ciula, Nicholas A. Gherardin, Michelle L. Giles, Tom P. Gordon, Samantha L. Grimley, Lana Horng, David C. Jackson, Jennifer A. Juno, Katherine Kedzierska, Stephen J. Kent, Sharon R. Lewin, Mason Littlejohn, Hayley A. McQuilten, Francesca L. Mordant, Thi H.O. Nguyen, Vanessa Pac Soo, Briony Price, Damian F.J. Purcell, Pradhipa Ramanathan, Samuel J. Redmond, Steven Rockman, Zheng Ruan, Joseph Sasadeusz, Julie A. Simpson, Kanta Subbarao, Stewart A. Fabb, Thomas J. Payne, Asuka Takanashi, Chee Wah Tan, Joseph Torresi, Jing Jing Wang, Lin-Fa Wang, Hareth Al-Wassiti, Chinn Yi Wong, Sophie Zaloumis, Colin W. Pouton, Dale I. Godfrey
Published in EBioMedicine (01.12.2023)
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Published in EBioMedicine (01.12.2023)
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Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations
Habel, Jennifer R, Chua, Brendon Y, Kedzierski, Lukasz, Selva, Kevin J, Damelang, Timon, Haycroft, Ebene R, Nguyen, Thi Ho, Koay, Hui-Fern, Nicholson, Suellen, McQuilten, Hayley A, Jia, Xiaoxiao, Allen, Lilith F, Hensen, Luca, Zhang, Wuji, van de Sandt, Carolien E, Neil, Jessica A, Pragastis, Katherine, Lau, Jillian Sy, Jumarang, Jaycee, Allen, E Kaitlynn, Amanant, Fatima, Krammer, Florian, Wragg, Kathleen M, Juno, Jennifer A, Wheatley, Adam K, Tan, Hyon-Xhi, Pell, Gabrielle, Walker, Susan, Audsley, Jennifer, Reynaldi, Arnold, Thevarajan, Irani, Denholm, Justin T, Subbarao, Kanta, Davenport, Miles P, Hogarth, P Mark, Godfrey, Dale I, Cheng, Allen C, Tong, Steven Yc, Bond, Katherine, Williamson, Deborah A, McMahon, James H, Thomas, Paul G, Pannaraj, Pia S, James, Fiona, Holmes, Natasha E, Smibert, Olivia C, Trubiano, Jason A, Gordon, Claire L, Chung, Amy W, Whitehead, Clare L, Kent, Stephen J, Lappas, Martha, Rowntree, Louise C, Kedzierska, Katherine
Published in JCI insight (10.04.2023)
Published in JCI insight (10.04.2023)
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Robust SARS-CoV-2 T cell responses with common TCRαβ motifs towards COVID-19 vaccines in haematological malignancy patients impacting B cell immunity
Nguyen, Thi H O, Rowntree, Louise C, Allen, Lilith F, Chua, Brendon Y, Kedzierski, Lukasz, Lim, Chhay, Lasica, Masa, Tennakoon, G Surekha, Saunders, Natalie R, Crane, Megan, Chee, Lynette, Seymour, John F, Anderson, Mary Ann, Whitechurch, Ashley, Clemens, E Bridie, Zhang, Wuji, Chang, So Young, Habel, Jennifer R, Jia, Xiaoxiao, McQuilten, Hayley A, Minervina, Anastasia A, Pogorelyy, Mikhail V, Chaurasia, Priyanka, Petersen, Jan, Menon, Tejas, Hensen, Luca, Neil, Jessica, Mordant, Francesca L, Tan, Hyon-Xhi, Cabug, Aira F, Wheatley, Adam K, Kent, Stephen J, Subbarao, Kanta, Karapanagiotidis, Theo, Huang, Han, Vo, Lynn K, Cain, Natalie L, Nicholson, Suellen, Krammer, Florian, Gibney, Grace, James, Fiona, Trevillyan, Janine M, Trubiano, Jason A, Mitchell, Jeni, Christensen, Britt, Bond, Katherine A, Williamson, Deborah A, Rossjohn, Jamie, Crawford, Jeremy Chase, Thomas, Paul G, Thursky, Karin A, Slavin, Monica A, Tam, Constantine S, Teh, Benjamin W, Kedzierska, Katherine
Published in Cell reports. Medicine (27.03.2023)
Published in Cell reports. Medicine (27.03.2023)
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