Bridging dolutegravir clinical viral response across doses and formulations using model-based exposure-response analysis in pediatrics
Chandasana, Hardik, Hayes, Siobhán, Buchanan, Ann M, Brothers, Cynthia, Wiznia, Andrew, Bartlett, Mattie, Popson, Stephanie, Townley, Ellen, George, Kathy, Vavro, Cindy, Ruel, Theodore, Acosta, Edward P, Singh, Rajendra
Published in AIDS (London) (15.07.2024)
Published in AIDS (London) (15.07.2024)
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Journal Article
Population pharmacokinetic modeling and simulation of maribavir to support dose selection and regulatory approval in adolescents with posttransplant refractory cytomegalovirus
Sun, Kefeng, Hayes, Siobhan, Farrell, Colm, Song, Ivy H.
Published in CPT: pharmacometrics and systems pharmacology (01.05.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.05.2023)
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Journal Article
Population Pharmacokinetic and Pharmacodynamic Modeling and Effects on Platelet Counts of Different Dosages of Eltrombopag in Chinese Patients With Chronic Primary Immune Thrombocytopenia
Wu, Kai, PhD, Thapar, Mita, PhD, Farrell, Colm, PhD, Hayes, Siobhan, PhD, Guo, Haiyi, MD, Hou, Ming, MD, Zhang, Jianping, PhD
Published in Clinical therapeutics (01.07.2015)
Published in Clinical therapeutics (01.07.2015)
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Journal Article
Model‐informed Evidence for Clinical Non‐inferiority of Every‐2‐Weeks Versus Standard Weekly Dosing Schedule of Cetuximab in Metastatic Colorectal Cancer
Milenković‐Grišić, Ana‐Marija, Hayes, Siobhán, Farrell, Colm, Kuroki, Yoshihiro, Bertolino, Mauro, Venkatakrishnan, Karthik, Girard, Pascal
Published in Clinical pharmacology and therapeutics (01.10.2024)
Published in Clinical pharmacology and therapeutics (01.10.2024)
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Journal Article
Population pharmacokinetics of dolutegravir in HIV‐infected treatment‐naive patients
Zhang, Jianping, Hayes, Siobhán, Sadler, Brian M., Minto, Ilisse, Brandt, Julie, Piscitelli, Steve, Min, Sherene, Song, Ivy H.
Published in British journal of clinical pharmacology (01.09.2015)
Published in British journal of clinical pharmacology (01.09.2015)
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Journal Article
Population Pharmacokinetic Analysis of Fluticasone Furoate/Umeclidinium Bromide/Vilanterol in Patients with Chronic Obstructive Pulmonary Disease
Mehta, Rashmi, Farrell, Colm, Hayes, Siobhán, Birk, Ruby, Okour, Malek, Lipson, David A.
Published in Clinical pharmacokinetics (01.01.2020)
Published in Clinical pharmacokinetics (01.01.2020)
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Journal Article
Population pharmacokinetics and exposure-response relationships of maribavir in transplant recipients with cytomegalovirus infection
Song, Ivy H, Chen, Grace, Hayes, Siobhan, Farrell, Colm, Jomphe, Claudia, Gosselin, Nathalie H, Sun, Kefeng
Published in Journal of pharmacokinetics and pharmacodynamics (27.09.2024)
Published in Journal of pharmacokinetics and pharmacodynamics (27.09.2024)
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Journal Article
Population Pharmacokinetic Modeling of Dolutegravir to Optimize Pediatric Dosing in HIV-1-Infected Infants, Children, and Adolescents
Chandasana, Hardik, Thapar, Mita, Hayes, Siobhan, Baker, Mark, Gibb, Diana M., Turkova, Anna, Ford, Deborah, Ruel, Theodore, Wiznia, Andrew, Fairlie, Lee, Bwakura-Dangarembizi, Mutsa, Mujuru, Hilda, Alvero, Carmelita, Farhad, Mona, Hazra, Rohan, Townley, Ellen, Buchanan, Ann, Bollen, Pauline, Waalewijn, Hylke, Colbers, Angela, Burger, David, Acosta, Edward P., Singh, Rajendra
Published in Clinical pharmacokinetics (01.10.2023)
Published in Clinical pharmacokinetics (01.10.2023)
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Journal Article
470 - Population Pharmacokinetics and Exposure–Response Relationships of Maribavir in Transplant Recipients with Cytomegalovirus Infections
Song, Ivy, Chen, Grace, Hayes, Siobhan, Farrell, Colm, Jomphe, Claudia, Gosselin, Nathalie H
Published in Transplantation and cellular therapy (01.03.2022)
Published in Transplantation and cellular therapy (01.03.2022)
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Journal Article
Population Pharmacokinetics and Exposure–Response Relationships of Maribavir in Transplant Recipients with Cytomegalovirus Infections
Song, Ivy, Chen, Grace, Hayes, Siobhan, Farrell, Colm, Jomphe, Claudia, Gosselin, Nathalie H
Published in Transplantation and cellular therapy (01.03.2022)
Published in Transplantation and cellular therapy (01.03.2022)
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Journal Article
Population PK/PD modeling of eltrombopag in healthy volunteers and patients with immune thrombocytopenic purpura and optimization of response-guided dosing
Hayes, Siobhan, Ouellet, Daniele, Zhang, Jianping, Wire, Mary B, Gibiansky, Ekaterina
Published in Journal of clinical pharmacology (01.10.2011)
Published in Journal of clinical pharmacology (01.10.2011)
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Journal Article
Population pharmacokinetic/pharmacodynamic modelling of eltrombopag in healthy volunteers and subjects with chronic liver disease: Pharmacokinetic/pharmacodynamic modelling of eltrombopag
Farrell, Colm, Hayes, Siobhan C., Wire, Mary, Zhang, Jianping
Published in British journal of clinical pharmacology (01.03.2014)
Published in British journal of clinical pharmacology (01.03.2014)
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Journal Article
Evaluation of the effect of dabrafenib and metabolites on QTc interval in patients with BRAF V600–mutant tumours
Nebot, Noelia, Arkenau, Hendrik‐Tobias, Infante, Jeffrey R., Chandler, Jason C., Weickhardt, Andrew, Lickliter, Jason D., Sarantopoulos, John, Gordon, Michael S., Mak, Gabriel, St‐Pierre, Annie, Tang, Lihua, Mookerjee, Bijoyesh, Carson, Stanley W., Hayes, Siobhan, Grossmann, Kenneth F.
Published in British journal of clinical pharmacology (01.04.2018)
Published in British journal of clinical pharmacology (01.04.2018)
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Journal Article
Population PK/PD modeling of eltrombopag in subjects with advanced solid tumors with chemotherapy-induced thrombocytopenia
Hayes, Siobhan, Mudd, Paul N., Ouellet, Daniele, Johnson, Brendan M., Williams, Daphne, Gibiansky, Ekaterina
Published in Cancer chemotherapy and pharmacology (01.06.2013)
Published in Cancer chemotherapy and pharmacology (01.06.2013)
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Journal Article
S0440 A Population Pharmacokinetic Analysis of Budesonide Oral Suspension in Children and Adults With Eosinophilic Esophagitis and Healthy Adult Volunteers
Song, Ivy H., Rodgers, Trudy, Hayes, Siobhán, Farrell, Colm
Published in The American journal of gastroenterology (01.10.2020)
Published in The American journal of gastroenterology (01.10.2020)
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