Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways
Dittmann, Jessica, Haydn, Tinka, Metzger, Patrick, Ward, George A., Boerries, Melanie, Vogler, Meike, Fulda, Simone
Published in Cell death and differentiation (01.06.2020)
Published in Cell death and differentiation (01.06.2020)
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Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation
Schulz-Fincke, Johannes, Hau, Mirjam, Barth, Jessica, Robaa, Dina, Willmann, Dominica, Kürner, Andreas, Haas, Julian, Greve, Gabriele, Haydn, Tinka, Fulda, Simone, Lübbert, Michael, Lüdeke, Steffen, Berg, Tobias, Sippl, Wolfgang, Schüle, Roland, Jung, Manfred
Published in European journal of medicinal chemistry (20.01.2018)
Published in European journal of medicinal chemistry (20.01.2018)
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BCL-2 selective inhibitor ABT-199 primes rhabdomyosarcoma cells to histone deacetylase inhibitor-induced apoptosis
Heinicke, Ulrike, Haydn, Tinka, Kehr, Sarah, Vogler, Meike, Fulda, Simone
Published in Oncogene (01.09.2018)
Published in Oncogene (01.09.2018)
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Abstract B81: Analogues of the chromenone namoline as inhibitors of lysine specific demethylase 1 (LSD1)
Schulz-Fincke, Johannes, Schmitt, Martin L., Carlino, Luca, Haydn, Tinka, Willmann, Dominica, Metzger, Eric, Fulda, Simone, Schüle, Roland, Sippl, Wolfgang, Jung, Manfred
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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