Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity
Ptacek, Jason, Hawtin, Rachael E, Sun, Dongmei, Louie, Brent, Evensen, Erik, Mittleman, Barbara B, Cesano, Alessandra, Cavet, Guy, Bingham, 3rd, Clifton O, Cofield, Stacey S, Curtis, Jeffrey R, Danila, Maria I, Raman, Chander, Furie, Richard A, Genovese, Mark C, Robinson, William H, Levesque, Marc C, Moreland, Larry W, Nigrovic, Peter A, Shadick, Nancy A, O'Dell, James R, Thiele, Geoffrey M, Clair, E William St, Striebich, Christopher C, Hale, Matthew B, Khalili, Houman, Batliwalla, Franak, Aranow, Cynthia, Mackay, Meggan, Diamond, Betty, Nolan, Garry P, Gregersen, Peter K, Bridges, Jr, S Louis
Published in PloS one (14.01.2021)
Published in PloS one (14.01.2021)
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Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia
Chen, Rong, Wierda, William G., Chubb, Sherri, Hawtin, Rachael E., Fox, Judith A., Keating, Michael J., Gandhi, Varsha, Plunkett, William
Published in Blood (07.05.2009)
Published in Blood (07.05.2009)
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Journal Article
Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II
Hawtin, Rachael E, Stockett, David E, Byl, Jo Ann W, McDowell, Robert S, Nguyen, Tan, Arkin, Michelle R, Conroy, Andrew, Yang, Wenjin, Osheroff, Neil, Fox, Judith A
Published in PloS one (15.04.2010)
Published in PloS one (15.04.2010)
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Baseline T cell dysfunction by single cell network profiling in metastatic breast cancer patients
Formenti, Silvia C, Hawtin, Rachael E, Dixit, Neha, Evensen, Erik, Lee, Percy, Goldberg, Judith D, Li, Xiaochun, Vanpouille-Box, Claire, Schaue, Dörthe, McBride, William H, Demaria, Sandra
Published in Journal for immunotherapy of cancer (11.07.2019)
Published in Journal for immunotherapy of cancer (11.07.2019)
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Journal Article
Filgotinib Demonstrates Efficacy in Rheumatoid Arthritis Independent of Smoking Status: Post Hoc Analysis of Phase 3 Trials and Claims-Based Analysis
Curtis, Jeffrey R., Emery, Paul, Downie, Bryan, Zhong, Yan, Liu, Jinfeng, Han, Ling, Hawtin, Rachael E., Burmester, Gerd Rüdiger
Published in Rheumatology and therapy. (01.02.2024)
Published in Rheumatology and therapy. (01.02.2024)
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Journal Article
AKT signaling as a novel factor associated with in vitro resistance of human AML to gemtuzumab ozogamicin
Rosen, David B, Harrington, Kimberly H, Cordeiro, James A, Leung, Ling Y, Putta, Santosh, Lacayo, Norman, Laszlo, George S, Gudgeon, Chelsea J, Hogge, Donna E, Hawtin, Rachael E, Cesano, Alessandra, Walter, Roland B
Published in PloS one (08.01.2013)
Published in PloS one (08.01.2013)
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Association between B-cell receptor responsiveness and disease progression in B-cell chronic lymphocytic leukemia: results from single cell network profiling studies
Cesano, Alessandra, Perbellini, Omar, Evensen, Erik, Chu, Charles C, Cioffi, Federica, Ptacek, Jason, Damle, Rajendra N, Chignola, Roberto, Cordeiro, James, Yan, Xiao-jie, Hawtin, Rachael E, Nichele, Ilaria, Ware, Jodi R, Cavallini, Chiara, Lovato, Ornella, Zanotti, Roberta, Rai, Kanti R, Chiorazzi, Nicholas, Pizzolo, Giovanni, Scupoli, Maria T
Published in Haematologica (Roma) (01.04.2013)
Published in Haematologica (Roma) (01.04.2013)
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Journal Article
Racial differences in B cell receptor signaling pathway activation
Longo, Diane M, Louie, Brent, Mathi, Kavita, Pos, Zoltan, Wang, Ena, Hawtin, Rachael E, Marincola, Francesco M, Cesano, Alessandra
Published in Journal of translational medicine (06.06.2012)
Published in Journal of translational medicine (06.06.2012)
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Journal Article
Functional pathway analysis using SCNP of FLT3 receptor pathway deregulation in AML provides prognostic information independent from mutational status
Cesano, Alessandra, Putta, Santosh, Rosen, David B, Cohen, Aileen C, Gayko, Urte, Mathi, Kavita, Woronicz, John, Hawtin, Rachael E, Cripe, Larry, Sun, Zhuoxin, Tallman, Martin S, Paietta, Elisabeth
Published in PloS one (19.02.2013)
Published in PloS one (19.02.2013)
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Journal Article
Single-cell network profiling of peripheral blood mononuclear cells from healthy donors reveals age- and race-associated differences in immune signaling pathway activation
Longo, Diane M, Louie, Brent, Putta, Santosh, Evensen, Erik, Ptacek, Jason, Cordeiro, James, Wang, Ena, Pos, Zoltan, Hawtin, Rachael E, Marincola, Francesco M, Cesano, Alessandra
Published in The Journal of immunology (1950) (15.02.2012)
Published in The Journal of immunology (1950) (15.02.2012)
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Journal Article
Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP)
Rosen, David B, Leung, Ling Y, Louie, Brent, Cordeiro, James A, Conroy, Andrew, Shapira, Iuliana, Fields, Scott Z, Cesano, Alessandra, Hawtin, Rachael E
Published in Journal of translational medicine (25.06.2014)
Published in Journal of translational medicine (25.06.2014)
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Journal Article
Voreloxin, a first-in-class anticancer quinolone derivative, acts synergistically with cytarabine in vitro and induces bone marrow aplasia in vivo
Scatena, Caroline D, Kumer, Jeffrey L, Arbitrario, Jennifer P, Howlett, Anthony R, Hawtin, Rachael E, Fox, Judith A, Silverman, Jeffrey A
Published in Cancer chemotherapy and pharmacology (01.10.2010)
Published in Cancer chemotherapy and pharmacology (01.10.2010)
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Journal Article
High-dimensional analysis of the aging immune system: verification of age-associated differences in immune signaling responses in healthy donors
Longo, Diane M, Louie, Brent, Ptacek, Jason, Friedland, Greg, Evensen, Erik, Putta, Santosh, Atallah, Michelle, Spellmeyer, David, Wang, Ena, Pos, Zoltan, Marincola, Francesco M, Schaeffer, Andrea, Lukac, Suzanne, Railkar, Radha, Beals, Chan R, Cesano, Alessandra, Carayannopoulos, Leonidas N, Hawtin, Rachael E
Published in Journal of translational medicine (21.06.2014)
Published in Journal of translational medicine (21.06.2014)
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Journal Article
Red-shifted excitation mutants of the green fluorescent protein
Delagrave, S, Hawtin, R E, Silva, C M, Yang, M M, Youvan, D C
Published in Bio/technology (New York, N.Y. 1983) (01.02.1995)
Published in Bio/technology (New York, N.Y. 1983) (01.02.1995)
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Journal Article
Inter-donor variation in cell subset specific immune signaling responses in healthy individuals
Longo, Diane M, Louie, Brent, Wang, Ena, Pos, Zoltan, Marincola, Francesco M, Hawtin, Rachael E, Cesano, Alessandra
Published in American journal of clinical and experimental immunology (01.01.2012)
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Published in American journal of clinical and experimental immunology (01.01.2012)
Journal Article
P204 Filgotinib demonstrates clinical efficacy in rheumatoid arthritis independent of smoking status: a post-hoc subgroup analysis of three Phase 3 clinical trials
Emery, Paul, Downie, Bryan, Liu, Jinfeng, Hawtin, Rachael E, Curtis, Jeffrey R, Burmester, Gerd R
Published in Rheumatology (Oxford, England) (23.04.2022)
Published in Rheumatology (Oxford, England) (23.04.2022)
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