The membrane associated accessory protein is an adeno-associated viral egress factor
Elmore, Zachary C., Patrick Havlik, L., Oh, Daniel K., Anderson, Leif, Daaboul, George, Devlin, Garth W., Vincent, Heather A., Asokan, Aravind
Published in Nature communications (29.10.2021)
Published in Nature communications (29.10.2021)
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Coevolution of Adeno-associated Virus Capsid Antigenicity and Tropism through a Structure-Guided Approach
Havlik, L Patrick, Simon, Katherine E, Smith, J Kennon, Klinc, Kelli A, Tse, Longping V, Oh, Daniel K, Fanous, Marco M, Meganck, Rita M, Mietzsch, Mario, Kleinschmidt, Jürgen, Agbandje-McKenna, Mavis, Asokan, Aravind
Published in Journal of virology (15.09.2020)
Published in Journal of virology (15.09.2020)
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Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing
Gonzalez, Trevor J., Simon, Katherine E., Blondel, Leo O., Fanous, Marco M., Roger, Angela L., Maysonet, Maribel Santiago, Devlin, Garth W., Smith, Timothy J., Oh, Daniel K., Havlik, L. Patrick, Castellanos Rivera, Ruth M., Piedrahita, Jorge A., ElMallah, Mai K., Gersbach, Charles A., Asokan, Aravind
Published in Nature communications (10.10.2022)
Published in Nature communications (10.10.2022)
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Capsid-mediated control of adeno-associated viral transcription determines host range
Loeb, Ezra J., Havlik, Patrick L., Elmore, Zachary C., Rosales, Alan, Fergione, Sophia M., Gonzalez, Trevor J., Smith, Timothy J., Benkert, Abigail R., Fiflis, David N., Asokan, Aravind
Published in Cell reports (Cambridge) (26.03.2024)
Published in Cell reports (Cambridge) (26.03.2024)
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Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion
Tse, Longping Victor, Klinc, Kelli A., Madigan, Victoria J., Rivera, Ruth M. Castellanos, Wells, Lindsey F., Havlik, L. Patrick, Smith, J. Kennon, Agbandje-McKenna, Mavis, Asokan, Aravind
Published in Proceedings of the National Academy of Sciences - PNAS (13.06.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (13.06.2017)
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Journal Article
Receptor Switching in Newly Evolved Adeno-associated Viruses
Havlik, L Patrick, Das, Anshuman, Mietzsch, Mario, Oh, Daniel K, Ark, Jonathan, McKenna, Robert, Agbandje-McKenna, Mavis, Asokan, Aravind
Published in Journal of virology (09.09.2021)
Published in Journal of virology (09.09.2021)
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An evolved AAV variant enables efficient genetic engineering of murine T cells
Nyberg, William A., Ark, Jonathan, To, Angela, Clouden, Sylvanie, Reeder, Gabriella, Muldoon, Joseph J., Chung, Jing-Yi, Xie, William H., Allain, Vincent, Steinhart, Zachary, Chang, Christopher, Talbot, Alexis, Kim, Sandy, Rosales, Alan, Havlik, L. Patrick, Pimentel, Harold, Asokan, Aravind, Eyquem, Justin
Published in Cell (19.01.2023)
Published in Cell (19.01.2023)
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