Development of Peptide-Based Probes for Molecular Imaging of the Postsynaptic Density in the Brain
Fernandes, Eduardo F. A., Palner, Mikael, Raval, Nakul Ravi, Jeppesen, Troels E., Danková, Daniela, Bærentzen, Simone L., Werner, Christian, Eilts, Janna, Maric, Hans M., Doose, Sören, Aripaka, Sanjay Sagar, Kaalund, Sanne Simone, Aznar, Susana, Kjaer, Andreas, Schlosser, Andreas, Haugaard-Kedström, Linda M., Knudsen, Gitte M., Herth, Matthias M., Stro̷mgaard, Kristian
Published in Journal of medicinal chemistry (25.07.2024)
Published in Journal of medicinal chemistry (25.07.2024)
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Journal Article
A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma
Haugaard-Kedström, Linda M, Clemmensen, Louise S, Sereikaite, Vita, Jin, Zeyu, Fernandes, Eduardo F. A, Wind, Bianca, Abalde-Gil, Flor, Daberger, Jan, Vistrup-Parry, Maria, Aguilar-Morante, Diana, Leblanc, Raphael, Egea-Jimenez, Antonio L, Albrigtsen, Marte, Jensen, Kamilla. E, Jensen, Thomas M. T, Ivarsson, Ylva, Vincentelli, Renaud, Hamerlik, Petra, Andersen, Jeanette Hammer, Zimmermann, Pascale, Lee, Weontae, Strømgaard, Kristian
Published in Journal of medicinal chemistry (11.02.2021)
Published in Journal of medicinal chemistry (11.02.2021)
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Journal Article
Targeting the APP-Mint2 Protein–Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid‑β Formation
Bartling, Christian R. O, Jensen, Thomas M. T, Henry, Shawna M, Colliander, Anna L, Sereikaite, Vita, Wenzler, Marcella, Jain, Palash, Maric, Hans M, Harpsøe, Kasper, Pedersen, Søren W, Clemmensen, Louise S, Haugaard-Kedström, Linda M, Gloriam, David E, Ho, Angela, Strømgaard, Kristian
Published in Journal of the American Chemical Society (20.01.2021)
Published in Journal of the American Chemical Society (20.01.2021)
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Journal Article
Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359
Zhang, Hang, Nielsen, Alexander L., Boesgaard, Michael W., Harpsøe, Kasper, Daly, Norelle L., Xiong, Xiao-Feng, Underwood, Christina R., Haugaard-Kedström, Linda M., Bräuner-Osborne, Hans, Gloriam, David E., Strømgaard, Kristian
Published in European journal of medicinal chemistry (05.08.2018)
Published in European journal of medicinal chemistry (05.08.2018)
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Journal Article
Design, Synthesis, and Characterization of a Single-Chain Peptide Antagonist for the Relaxin-3 Receptor RXFP3
Haugaard-Kedström, Linda M, Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J, Ryan, Philip J, Craik, David J, Gundlach, Andrew L, Wade, John D, Bathgate, Ross A. D, Rosengren, K. Johan
Published in Journal of the American Chemical Society (06.04.2011)
Published in Journal of the American Chemical Society (06.04.2011)
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Journal Article
Probing the Mint2 Protein–Protein Interaction Network Relevant to the Pathophysiology of Alzheimer's Disease
Jensen, Thomas M. T., Albertsen, Louise, Bartling, Christian R. O., Haugaard‐Kedström, Linda M., Strømgaard, Kristian
Published in Chembiochem : a European journal of chemical biology (04.06.2018)
Published in Chembiochem : a European journal of chemical biology (04.06.2018)
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Journal Article
Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors
Foster, Simon R., Hauser, Alexander S., Vedel, Line, Strachan, Ryan T., Huang, Xi-Ping, Gavin, Ariana C., Shah, Sushrut D., Nayak, Ajay P., Haugaard-Kedström, Linda M., Penn, Raymond B., Roth, Bryan L., Bräuner-Osborne, Hans, Gloriam, David E.
Published in Cell (31.10.2019)
Published in Cell (31.10.2019)
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Journal Article
Solution Structure, Aggregation Behavior, and Flexibility of Human Relaxin‑2
Haugaard-Kedström, Linda M, Hossain, Mohammed Akhter, Daly, Norelle L, Bathgate, Ross A. D, Rinderknecht, Ernst, Wade, John D, Craik, David J, Rosengren, K. Johan
Published in ACS chemical biology (20.03.2015)
Published in ACS chemical biology (20.03.2015)
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Journal Article
Targeting protein-protein interactions with trimeric ligands: high affinity inhibitors of the MAGUK protein family
Nissen, Klaus B, Haugaard-Kedström, Linda M, Wilbek, Theis S, Nielsen, Line S, Åberg, Emma, Kristensen, Anders S, Bach, Anders, Jemth, Per, Strømgaard, Kristian
Published in PloS one (06.02.2015)
Published in PloS one (06.02.2015)
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Journal Article
PDZ Domains as Drug Targets
Christensen, Nikolaj R, Čalyševa, Jelena, Fernandes, Eduardo F A, Lüchow, Susanne, Clemmensen, Louise S, Haugaard-Kedström, Linda M, Strømgaard, Kristian
Published in Advanced therapeutics (01.07.2019)
Published in Advanced therapeutics (01.07.2019)
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Journal Article
Molecular Details of a Coupled Binding and Folding Reaction between the Amyloid Precursor Protein and a Folded Domain
Jensen, Thomas M. T, Bartling, Christian R. O, Karlsson, O. Andreas, Åberg, Emma, Haugaard-Kedström, Linda M, Strømgaard, Kristian, Jemth, Per
Published in ACS chemical biology (16.07.2021)
Published in ACS chemical biology (16.07.2021)
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Journal Article
Importance of a Conserved Lys/Arg Residue for Ligand/PDZ Domain Interactions as Examined by Protein Semisynthesis
Pedersen, Søren W., Moran, Griffin E., Sereikaitė, Vita, Haugaard-Kedström, Linda M., Strømgaard, Kristian
Published in Chembiochem : a European journal of chemical biology (17.10.2016)
Published in Chembiochem : a European journal of chemical biology (17.10.2016)
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Journal Article
Design, Synthesis, and Characterization of Fatty Acid Derivatives of a Dimeric Peptide-Based Postsynaptic Density-95 (PSD-95) Inhibitor
Nissen, Klaus B, Andersen, Julie J, Haugaard-Kedström, Linda M, Bach, Anders, Strømgaard, Kristian
Published in Journal of medicinal chemistry (12.02.2015)
Published in Journal of medicinal chemistry (12.02.2015)
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Journal Article
Development of Relaxin-3 Agonists and Antagonists Based on Grafted Disulfide-Stabilized Scaffolds
Lee, Han Siean, Postan, Michael, Song, Angela, Clark, Richard J, Bathgate, Ross A D, Haugaard-Kedström, Linda M, Rosengren, K Johan
Published in Frontiers in chemistry (18.02.2020)
Published in Frontiers in chemistry (18.02.2020)
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Journal Article
The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance
Andersson, Håkan S., Figueredo, Sharel M., Haugaard-Kedström, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, André J., Rosengren, K. Johan
Published in Amino acids (01.10.2012)
Published in Amino acids (01.10.2012)
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Journal Article
Mechanism and site of action of big dynorphin on ASIC1a
Borg, Christian B., Braun, Nina, Heusser, Stephanie A., Bay, Yasmin, Weis, Daniel, Galleano, Iacopo, Lund, Camilla, Tian, Weihua, Haugaard-Kedström, Linda M., Bennett, Eric P., Lynagh, Timothy, Strømgaard, Kristian, Andersen, Jacob, Pless, Stephan A.
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2020)
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A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity
Nilsson, Per H, Johnson, Christina, Quach, Quang Huy, Macpherson, Alex, Durrant, Oliver, Pischke, Soeren E, Fure, Hilde, Landsem, Anne, Bergseth, Grethe, Schjalm, Camilla, Haugaard-Kedström, Linda M, Huber-Lang, Markus, van den Elsen, Jean, Brekke, Ole-Lars, Mollnes, Tom Eirik
Published in The Journal of immunology (1950) (15.09.2021)
Published in The Journal of immunology (1950) (15.09.2021)
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Journal Article
Chemically synthesized dicarba H2 relaxin analogues retain strong RXFP1 receptor activity but show an unexpected loss of in vitro serum stability
Hossain, Mohammed Akhter, Haugaard-Kedström, Linda M, Rosengren, K. Johan, Bathgate, Ross A. D, Wade, John D
Published in Organic & biomolecular chemistry (28.11.2015)
Published in Organic & biomolecular chemistry (28.11.2015)
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Journal Article
Binding conformation and determinants of a single-chain peptide antagonist at the relaxin-3 receptor RXFP3
Haugaard-Kedström, Linda M., Lee, Han Siean, Jones, Maryon V., Song, Angela, Rathod, Vishaal, Hossain, Mohammed Akhter, Bathgate, Ross A.D., Rosengren, K. Johan
Published in The Journal of biological chemistry (12.10.2018)
Published in The Journal of biological chemistry (12.10.2018)
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