The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors
Sato, Mayo, Liebschner, Dorothee, Yamada, Yusuke, Matsugaki, Naohiro, Arakawa, Takatoshi, Wills, Siobhán S., Hattie, Mitchell, Stubbs, Keith A., Ito, Tasuku, Senda, Toshiya, Ashida, Hisashi, Fushinobu, Shinya
Published in The Journal of biological chemistry (21.07.2017)
Published in The Journal of biological chemistry (21.07.2017)
Get full text
Journal Article
Modifying the phenyl group of PUGNAc: reactivity tuning to deliver selective inhibitors for N-acetyl-D-glucosaminidases
Hattie, Mitchell, Cekic, Nevena, Debowski, Aleksandra W., Vocadlo, David J., Stubbs, Keith A.
Published in Organic & biomolecular chemistry (01.01.2016)
Published in Organic & biomolecular chemistry (01.01.2016)
Get full text
Journal Article
Crystal Structures of a Glycoside Hydrolase Family 20 Lacto-N-biosidase from Bifidobacterium bifidum
Ito, Tasuku, Katayama, Takane, Hattie, Mitchell, Sakurama, Haruko, Wada, Jun, Suzuki, Ryuichiro, Ashida, Hisashi, Wakagi, Takayoshi, Yamamoto, Kenji, Stubbs, Keith A., Fushinobu, Shinya
Published in The Journal of biological chemistry (26.04.2013)
Published in The Journal of biological chemistry (26.04.2013)
Get full text
Journal Article
Molecular Insight into Evolution of Symbiosis between Breast-Fed Infants and a Member of the Human Gut Microbiome Bifidobacterium longum
Yamada, Chihaya, Gotoh, Aina, Sakanaka, Mikiyasu, Hattie, Mitchell, Stubbs, Keith A., Katayama-Ikegami, Ayako, Hirose, Junko, Kurihara, Shin, Arakawa, Takatoshi, Kitaoka, Motomitsu, Okuda, Shujiro, Katayama, Takane, Fushinobu, Shinya
Published in Cell chemical biology (20.04.2017)
Published in Cell chemical biology (20.04.2017)
Get full text
Journal Article
Synergistic activity of fosfomycin, β-lactams and peptidoglycan recycling inhibition against Pseudomonas aeruginosa
Hamou-Segarra, Myriam, Zamorano, Laura, Vadlamani, Grishma, Chu, Mitchell, Sanchez-Diener, Irina, Juan, Carlos, Blazquez, Jesús, Hattie, Mitchell, Stubbs, Keith A, Mark, Brian L, Oliver, Antonio
Published in Journal of antimicrobial chemotherapy (01.02.2017)
Published in Journal of antimicrobial chemotherapy (01.02.2017)
Get full text
Journal Article
Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis
Hattie, Mitchell, Ito, Tasuku, Debowski, Aleksandra W., Arakawa, Takatoshi, Katayama, Takane, Yamamoto, Kenji, Fushinobu, Shinya, Stubbs, Keith A.
Published in Chemical communications (Cambridge, England) (18.10.2015)
Published in Chemical communications (Cambridge, England) (18.10.2015)
Get full text
Journal Article
Modifying the phenyl group of PUGNAc: reactivity tuning to deliver selective inhibitors for N-acetyl-d-glucosaminidasesDedicated to the memory of Associate Professor Emilio Ghisalberti.Electronic supplementary information (ESI) available. See DOI: 10.1039/c6ob00297h
Hattie, Mitchell, Cekic, Nevena, Debowski, Aleksandra W, Vocadlo, David J, Stubbs, Keith A
Year of Publication 15.03.2016
Year of Publication 15.03.2016
Get full text
Journal Article
Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysisElectronic supplementary information (ESI) available. See DOI: 10.1039/c5cc05494j
Hattie, Mitchell, Ito, Tasuku, Debowski, Aleksandra W, Arakawa, Takatoshi, Katayama, Takane, Yamamoto, Kenji, Fushinobu, Shinya, Stubbs, Keith A
Year of Publication 29.09.2015
Year of Publication 29.09.2015
Get full text
Journal Article
Inhibition of the family 20 glycoside hydrolase catalytic modules in the Streptococcus pneumoniae exo-β-d-N-acetylglucosaminidase, StrHElectronic supplementary information (ESI) available: Data processing, refinement statistics, and model statistics tables. See DOI: 10.1039/c3ob41579a
Pluvinage, Benjamin, Stubbs, Keith A, Hattie, Mitchell, Vocadlo, David J, Boraston, Alisdair B
Year of Publication 29.10.2013
Year of Publication 29.10.2013
Get full text
Journal Article
Inhibition of the family 20 glycoside hydrolase catalytic modules in the Streptococcus pneumoniae exo-β-D-N-acetylglucosaminidase, StrH
Pluvinage, Benjamin, Stubbs, Keith A, Hattie, Mitchell, Vocadlo, David J, Boraston, Alisdair B
Published in Organic & biomolecular chemistry (07.12.2013)
Published in Organic & biomolecular chemistry (07.12.2013)
Get full text
Journal Article