A thiol probe for measuring unfolded protein load and proteostasis in cells
Chen, Moore Z., Moily, Nagaraj S., Bridgford, Jessica L., Wood, Rebecca J., Radwan, Mona, Smith, Trevor A., Song, Zhegang, Tang, Ben Zhong, Tilley, Leann, Xu, Xiaohong, Reid, Gavin E., Pouladi, Mahmoud A., Hong, Yuning, Hatters, Danny M.
Published in Nature communications (07.09.2017)
Published in Nature communications (07.09.2017)
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Journal Article
Hidden information on protein function in censuses of proteome foldedness
Cox, Dezerae, Ang, Ching-Seng, Nillegoda, Nadinath B., Reid, Gavin E., Hatters, Danny M.
Published in Nature communications (14.04.2022)
Published in Nature communications (14.04.2022)
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Journal Article
Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal
Hidalgo San Jose, Lorena, Sunshine, Mary Jean, Dillingham, Christopher H., Chua, Bernadette A., Kruta, Miriama, Hong, Yuning, Hatters, Danny M., Signer, Robert A.J.
Published in Cell reports (Cambridge) (07.01.2020)
Published in Cell reports (Cambridge) (07.01.2020)
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Journal Article
Protein aggregation in cell biology: An aggregomics perspective of health and disease
Cox, Dezerae, Raeburn, Candice, Sui, Xiaojing, Hatters, Danny M.
Published in Seminars in cell & developmental biology (01.03.2020)
Published in Seminars in cell & developmental biology (01.03.2020)
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Journal Article
A biosensor-based framework to measure latent proteostasis capacity
Wood, Rebecca J., Ormsby, Angelique R., Radwan, Mona, Cox, Dezerae, Sharma, Abhishek, Vöpel, Tobias, Ebbinghaus, Simon, Oliveberg, Mikael, Reid, Gavin E., Dickson, Alex, Hatters, Danny M.
Published in Nature communications (18.01.2018)
Published in Nature communications (18.01.2018)
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Journal Article
Nascent mutant Huntingtin exon 1 chains do not stall on ribosomes during translation but aggregates do recruit machinery involved in ribosome quality control and RNA
Ormsby, Angelique R, Cox, Dezerae, Daly, James, Priest, David, Hinde, Elizabeth, Hatters, Danny M, Borchelt, David R
Published in PloS one (31.07.2020)
Published in PloS one (31.07.2020)
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Longitudinal spatial mapping of lipid metabolites reveals pre-symptomatic changes in the hippocampi of Huntington's disease transgenic mice
Farzana, Farheen, McConville, Malcolm J., Renoir, Thibault, Li, Shanshan, Nie, Shuai, Tran, Harvey, Hannan, Anthony J., Hatters, Danny M., Boughton, Berin A.
Published in Neurobiology of disease (01.01.2023)
Published in Neurobiology of disease (01.01.2023)
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Journal Article
Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis
Ramdzan, Yasmin M., Trubetskov, Mikhail M., Ormsby, Angelique R., Newcombe, Estella A., Sui, Xiaojing, Tobin, Mark J., Bongiovanni, Marie N., Gras, Sally L., Dewson, Grant, Miller, Jason M.L., Finkbeiner, Steven, Moily, Nagaraj S., Niclis, Jonathan, Parish, Clare L., Purcell, Anthony W., Baker, Michael J., Wilce, Jacqueline A., Waris, Saboora, Stojanovski, Diana, Böcking, Till, Ang, Ching-Seng, Ascher, David B., Reid, Gavin E., Hatters, Danny M.
Published in Cell reports (Cambridge) (02.05.2017)
Published in Cell reports (Cambridge) (02.05.2017)
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Immiscible inclusion bodies formed by polyglutamine and poly(glycine-alanine) are enriched with distinct proteomes but converge in proteins that are risk factors for disease and involved in protein degradation
Radwan, Mona, Lilley, Jordan D, Ang, Ching-Seng, Reid, Gavin E, Hatters, Danny M
Published in PloS one (28.08.2020)
Published in PloS one (28.08.2020)
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Journal Article
Tyrosine 416 is phosphorylated in the closed, repressed conformation of c-Src
Irtegun, Sevgi, Wood, Rebecca J, Ormsby, Angelique R, Mulhern, Terrence D, Hatters, Danny M
Published in PloS one (26.07.2013)
Published in PloS one (26.07.2013)
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Journal Article
SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation
Lee, Jodi A, Yerbury, Justin J, Farrawell, Natalie, Shearer, Robert F, Constantinescu, Patrick, Hatters, Danny M, Schroder, Wayne A, Suhrbier, Andreas, Wilson, Mark R, Saunders, Darren N, Ranson, Marie
Published in PloS one (17.06.2015)
Published in PloS one (17.06.2015)
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Journal Article
AMP-Activated Protein Kinase β-Subunit Requires Internal Motion for Optimal Carbohydrate Binding
Bieri, Michael, Mobbs, Jesse I., Koay, Ann, Louey, Gavin, Mok, Yee-Foong, Hatters, Danny M., Park, Jong-Tae, Park, Kwan-Hwa, Neumann, Dietbert, Stapleton, David, Gooley, Paul R.
Published in Biophysical journal (18.01.2012)
Published in Biophysical journal (18.01.2012)
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Journal Article
Macromolecular Crowding Accelerates Amyloid Formation by Human Apolipoprotein C-II
Hatters, Danny M., Minton, Allen P., Howlett, Geoffrey J.
Published in The Journal of biological chemistry (08.03.2002)
Published in The Journal of biological chemistry (08.03.2002)
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Journal Article
The anti-cancer IgM monoclonal antibody PAT-SM6 binds with high avidity to the unfolded protein response regulator GRP78
Rosenes, Zachary, Mulhern, Terrence D, Hatters, Danny M, Ilag, Leodevico L, Power, Barbara E, Hosking, Chris, Hensel, Frank, Howlett, Geoffrey J, Mok, Yee-Foong
Published in PloS one (19.09.2012)
Published in PloS one (19.09.2012)
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Journal Article
Fibrillar Amyloid Protein Present in Atheroma Activates CD36 Signal Transduction
Medeiros, Lea A., Khan, Tayeba, El Khoury, Joseph B., Pham, Chi L.L., Hatters, Danny M., Howlett, Geoffrey J., Lopez, Roland, O’Brien, Kevin D., Moore, Kathryn J.
Published in The Journal of biological chemistry (12.03.2004)
Published in The Journal of biological chemistry (12.03.2004)
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