Targeting the Binding Function 3 (BF3) Site of the Androgen Receptor Through Virtual Screening. 2. Development of 2‑((2-phenoxyethyl) thio)‑1H‑benzimidazole Derivatives
Munuganti, Ravi Shashi Nayana, Leblanc, Eric, Axerio-Cilies, Peter, Labriere, Christophe, Frewin, Kate, Singh, Kriti, Hassona, Mohamed D. H, Lack, Nathan A, Li, Huifang, Ban, Fuqiang, Tomlinson Guns, Emma, Young, Robert, Rennie, Paul S, Cherkasov, Artem
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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Journal Article
Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis
Elnakish, Mohammad T, Hassona, Mohamed D H, Alhaj, Mazin A, Moldovan, Leni, Janssen, Paul M L, Khan, Mahmood, Hassanain, Hamdy H
Published in PloS one (24.08.2012)
Published in PloS one (24.08.2012)
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Vascular Hypertrophy and Hypertension Caused by Transgenic Overexpression of Profilin 1
Moustafa-Bayoumi, Moustafa, Alhaj, Mazin A., El-Sayed, Osama, Wisel, Sheik, Chotani, Maqsood A., Abouelnaga, Zeinb A., Hassona, Mohamed D.H., Rigatto, Katya, Morris, Mariana, Nuovo, Gerard, Zweier, Jay L., Goldschmidt-Clermont, Pascal, Hassanain, Hamdy
Published in The Journal of biological chemistry (28.12.2007)
Published in The Journal of biological chemistry (28.12.2007)
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Journal Article
In vitro assessment of clevidipine using the profilin1 hypertensive mouse model
Hassanain, Hamdy H, Hassona, Mohamed D H, Puente, Erika G, Sun, Chengwen, Abouelnaga, Zeinb A, Tulman, David B, Bergese, Sergio D
Published in Pharmaceuticals (Basel, Switzerland) (29.04.2013)
Published in Pharmaceuticals (Basel, Switzerland) (29.04.2013)
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Journal Article
Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation
Lallous, Nada, Leblanc, Eric, Munuganti, Ravi S N, Hassona, Mohamed D H, Nakouzi, Nader Al, Awrey, Shannon, Morin, Helene, Roshan-Moniri, Mani, Singh, Kriti, Lawn, Sam, Yamazaki, Takeshi, Adomat, Hans H, Andre, Christophe, Daugaard, Mads, Young, Robert N, Guns, Emma S Tomlinson, Rennie, Paul S, Cherkasov, Artem
Published in Molecular cancer therapeutics (01.12.2016)
Published in Molecular cancer therapeutics (01.12.2016)
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Journal Article
Characterization of a new class of androgen receptor antagonists with potential therapeutic application in advanced prostate cancer
Li, Huifang, Hassona, Mohamed D H, Lack, Nathan A, Axerio-Cilies, Peter, Leblanc, Eric, Tavassoli, Peyman, Kanaan, Natalia, Frewin, Kate, Singh, Kriti, Adomat, Hans, Böhm, Konrad J, Prinz, Helge, Guns, Emma Tomlinson, Rennie, Paul S, Cherkasov, Artem
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
Cardiac remodeling caused by transgenic overexpression of a corn Rac gene
Elnakish, Mohammad T, Awad, Mohamed M, Hassona, Mohamed D H, Alhaj, Mazin A, Kulkarni, Aditi, Citro, Lucas A, Sayyid, Muzzammil, Abouelnaga, Zeinb A, El-Sayed, Osama, Kuppusamy, Periannan, Moldovan, Leni, Khan, Mahmood, Hassanain, Hamdy H
Published in American journal of physiology. Heart and circulatory physiology (01.09.2011)
Published in American journal of physiology. Heart and circulatory physiology (01.09.2011)
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Journal Article
Vascular hypertrophy-associated hypertension of profilin1 transgenic mouse model leads to functional remodeling of peripheral arteries
Hassona, Mohamed D H, Abouelnaga, Zeinb A, Elnakish, Mohammad T, Awad, Mohamed M, Alhaj, Mazin, Goldschmidt-Clermont, Pascal J, Hassanain, Hamdy
Published in American journal of physiology. Heart and circulatory physiology (01.06.2010)
Published in American journal of physiology. Heart and circulatory physiology (01.06.2010)
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Journal Article
The effect of selective antihypertensive drugs on the vascular remodeling-associated hypertension: insights from a profilin1 transgenic mouse model
Hassona, Mohamed D H, Elnakish, Mohammad T, Abouelnaga, Zeinb A, Alhaj, Mazin, Wani, Altaf A, Hassanain, Hamdy
Published in Journal of cardiovascular pharmacology (01.05.2011)
Published in Journal of cardiovascular pharmacology (01.05.2011)
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Journal Article
Abstract 5130: Assessment of the antitumor activity of leech (huridinaria manillensis) saliva extract in prostate cancer
Ammar, Amr E., Hassona, Mohamed H., Meckling, Gray R., Chan, Leslie G., Chin, Mei Y., Abdualkader, Abdulrahman, Alaama, Mohamed, Merzouk, Ahmed, Helaluddin, Abulbashar, Ghawi, Abbas, Kucuk, Omer, Guns, Emma S.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Identification of a Potent Antiandrogen that Targets the BF3 Site of the Androgen Receptor and Inhibits Enzalutamide-Resistant Prostate Cancer
Munuganti, Ravi S.N., Hassona, Mohamed D.H., Leblanc, Eric, Frewin, Kate, Singh, Kriti, Ma, Dennis, Ban, Fuqiang, Hsing, Michael, Adomat, Hans, Lallous, Nada, Andre, Christophe, Jonadass, Jon Paul Selvam, Zoubeidi, Amina, Young, Robert N., Tomlinson Guns, Emma, Rennie, Paul S., Cherkasov, Artem
Published in Chemistry & biology (20.11.2014)
Published in Chemistry & biology (20.11.2014)
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Journal Article
Targeting the Binding Function 3 (BF3) Site of the Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1 H -benzimidazole Derivatives
Munuganti, Ravi Shashi Nayana, Leblanc, Eric, Axerio-Cilies, Peter, Labriere, Christophe, Frewin, Kate, Singh, Kriti, Hassona, Mohamed D. H., Lack, Nathan A., Li, Huifang, Ban, Fuqiang, Tomlinson Guns, Emma, Young, Robert, Rennie, Paul S., Cherkasov, Artem
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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Journal Article
Abstract 3654: Targeting binding function-3 site on the androgen receptor to treat Enzalutamide-resistant prostate cancer
Munuganti, Ravi Shashi Nayana, Hassona, Mohamed DH, Leblanc, Eric, Guns, Emma T., Rennie, Paul S., Cherkasov, Artem
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Cardiac remodeling caused by transgenic overexpression of a corn Rac gene
ELNAKISH, Mohammad T, AWAD, Mohamed M, MOLDOVAN, Leni, KHAN, Mahmood, HASSANAIN, Hamdy H, HASSONA, Mohamed D. H, ALHAJ, Mazin A, KULKARNI, Aditi, CITRO, Lucas A, SAYYID, Muzzammil, ABOUELNAGA, Zeinb A, EL-SAYED, Osama, KUPPUSAMY, Periannan
Published in American journal of physiology. Heart and circulatory physiology (2011)
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Published in American journal of physiology. Heart and circulatory physiology (2011)
Journal Article
Vascular hypertrophy-associated hypertension of profilinl transgenic mouse model leads to functional remodeling of peripheral arteries
HASSONA, Mohamed D. H, ABOUELNAGA, Zeinb A, ELNAKISH, Mohammad T, AWAD, Mohamed M, ALHAJ, Mazin, GOLDSCHMIDT-CLERMONT, Pascal J, HASSANAIN, Hamdy
Published in American journal of physiology. Heart and circulatory physiology (2010)
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Published in American journal of physiology. Heart and circulatory physiology (2010)
Journal Article
Abstract 1727: DNA-binding domain as an alternative target site on androgen receptor for prostate cancer therapy: Pre-clinical in vivo study of a novel small molecule for drug development
Hassona, Mohamed DH, Chan, Leslie G., Meckling, Gray R., Li, Huifang, LeBlanc, Eric, Ban, Fuqiang, Cherkasov, Artem, Rennie, Paul S., Guns, Emma
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 1632: Discovery of a novel series of androgen receptor antagonists with potential therapeutic applications in castration-resistant prostate cancer
Li, Huifang, Hassona, Mohamed DH, Lack, Nathan A., Axerio-Cilies, Peter, Leblanc, Eric, Guns, Emma T., Rennie, Paul S., Cherkasov, Artem
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract 2508: The development of anti-androgens with a novel mechanism of action for treatment of castration-resistant prostate cancer
Munuganti, Ravi Shashi Nayana, Hassona, Mohamed DH, Leblanc, Eric, Ban, Fuqiang, Guns, Emma T., Rennie, Paul S., Cherkasov, Artem
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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