Identification of Novel Aryl Carboxamide Derivatives as Death-Associated Protein Kinase 1 (DAPK1) Inhibitors with Anti-Proliferative Activities: Design, Synthesis, In Vitro, and In Silico Biological Studies
Elkamhawy, Ahmed, Paik, Sora, Ali, Eslam M. H, Hassan, Ahmed H. E, Kang, So Jin, Lee, Kyeong, Roh, Eun Joo
Published in Pharmaceuticals (Basel, Switzerland) (25.08.2022)
Published in Pharmaceuticals (Basel, Switzerland) (25.08.2022)
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In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases
Hassan, Ahmed H E, El-Sayed, Selwan M, Yamamoto, Mizuki, Gohda, Jin, Matsumoto, Takehisa, Shirouzu, Mikako, Inoue, Jun-Ichiro, Kawaguchi, Yasushi, Mansour, Reem M A, Anvari, Abtin, Farahat, Abdelbasset A
Published in Viruses (15.05.2023)
Published in Viruses (15.05.2023)
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Repurposing Synthetic Congeners of a Natural Product Aurone Unveils a Lead Antitumor Agent Inhibiting Folded P-Loop Conformation of MET Receptor Tyrosine Kinase
Hassan, Ahmed H. E, Wang, Cai Yi, Lee, Cheol Jung, Jeon, Hye Rim, Choi, Yeonwoo, Moon, Suyeon, Lee, Chae Hyeon, Kim, Yeon Ju, Cho, Soo Bin, Mahmoud, Kazem, El-Sayed, Selwan M, Lee, Sang Kook, Lee, Yong Sup
Published in Pharmaceuticals (Basel, Switzerland) (01.11.2023)
Published in Pharmaceuticals (Basel, Switzerland) (01.11.2023)
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Investigating the structure-activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors
El-Demerdash, Amr, Al-Karmalawy, Ahmed A, Abdel-Aziz, Tarek Mohamed, Elhady, Sameh S, Darwish, Khaled M, Hassan, Ahmed H. E
Published in RSC advances (22.09.2021)
Published in RSC advances (22.09.2021)
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Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases
Hassan, Ahmed H. E., Kim, Hyeon Jeong, Gee, Min Sung, Park, Jong-Hyun, Jeon, Hye Rim, Lee, Cheol Jung, Choi, Yeonwoo, Moon, Suyeon, Lee, Danbi, Lee, Jong Kil, Park, Ki Duk, Lee, Yong Sup
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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Journal Article
Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds
Farag, Ahmed K., Hassan, Ahmed H. E., Ahn, Byung Sun, Park, Ki Duk, Roh, Eun Joo
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase
Hassan, Ahmed H. E., Oh, Yeon Il, Lee, Chae Hyeon, Kim, Yeon Ju, Cho, Soo Bin, Alam, Md. Maqusood, Park, Sang-Eun, Chung, Kyung-Sook, Lee, Kyung-Tae, Lee, Yong Sup
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
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Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development of potential treatment of Leishmania donovani
Hassan, Ahmed H. E., Phan, Trong-Nhat, Yoon, Seolmin, Lee, Cheol Jung, Jeon, Hye Rim, Kim, Seung-Hwan, No, Joo Hwan, Lee, Yong Sup
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
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Escaping ESKAPE resistance: in vitro and in silico studies of multifunctional carbamimidoyl-tethered indoles against antibiotic-resistant bacteria
Gulia, Kanika, Hassan, Ahmed H E, Lenhard, Justin R, Farahat, Abdelbasset A
Published in Royal Society open science (19.04.2023)
Published in Royal Society open science (19.04.2023)
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Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani
Hassan, Ahmed H. E., Bayoumi, Waleed A., El-Sayed, Selwan M., Phan, Trong-Nhat, Kim, Yeon Ju, Lee, Chae Hyeon, Cho, Soo Bin, Oh, Taegeun, Ham, Gyeongpyo, Mahmoud, Kazem, No, Joo Hwan, Lee, Yong Sup
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
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Enantiopure methoxetamine stereoisomers: chiral resolution, conformational analysis, UV-circular dichroism spectroscopy and electronic circular dichroism
Lee, Kun Won, Hassan, Ahmed H. E, Jeong, Youngdo, Yoon, Seolmin, Kim, Seung-Hwan, Lee, Cheol Jung, Jeon, Hye Rim, Chang, Suk Woo, Kim, Ji-Young, Jang, Dae Sik, Kim, Hee Jin, Cheong, Jae Hoon, Lee, Yong Sup
Published in New journal of chemistry (08.03.2021)
Published in New journal of chemistry (08.03.2021)
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Nitrogen-doped carbon quantum dots as a novel treatment for black fungal bone infections (Mucormycosis): in vitro and in vivo study
Belal, Amany, Almalki, Atiah H, Farghali, Ahmed A, Mahmoud, Rehab, Atta, R R, Allah, Abeer Enaiet, Hassan, Walid Hamdy, Lee, Sangmin, Kotp, Amna A, Essam, Doaa, Hassan, Ahmed H E, Ghoneim, Mohammed M, Abo El-Ela, Fatma I, Abdelwahab, Abdalla
Published in Artificial cells, nanomedicine, and biotechnology (01.12.2024)
Published in Artificial cells, nanomedicine, and biotechnology (01.12.2024)
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A Novel Hydroxyapatite/Vitamin B12 Nanoformula for Treatment of Bone Damage: Preparation, Characterization, and Anti-Arthritic, Anti-Inflammatory, and Antioxidant Activities in Chemically Induced Arthritic Rats
Belal, Amany, Mahmoud, Rehab, Mohamed, Eman E., Farghali, Ahmed, Abo El-Ela, Fatma I., Gamal, Amr, Halfaya, Fatma Mohamed, Khaled, Esraa, Farahat, Abdelbasset A., Hassan, Ahmed H. E., Ghoneim, Mohammed M., Taha, Mohamed, Zaky, Mohamed Y.
Published in Pharmaceuticals (Basel, Switzerland) (06.04.2023)
Published in Pharmaceuticals (Basel, Switzerland) (06.04.2023)
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Design, Rational Repurposing, Synthesis, In Vitro Evaluation, Homology Modeling and In Silico Study of Sulfuretin Analogs as Potential Antileishmanial Hit Compounds
Hassan, Ahmed H.E, Phan, Trong-Nhat, Choi, Yeonwoo, Moon, Suyeon, No, Joo Hwan, Lee, Yong Sup
Published in Pharmaceuticals (Basel, Switzerland) (26.08.2022)
Published in Pharmaceuticals (Basel, Switzerland) (26.08.2022)
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Integrating computational methods guided the discovery of phytochemicals as potential Pin1 inhibitors for cancer: pharmacophore modeling, molecular docking, MM-GBSA calculations and molecular dynamics studies
Alzain, Abdulrahim A, Elbadwi, Fatima A, Shoaib, Tagyedeen H, Sherif, Asmaa E, Osman, Wadah, Ashour, Ahmed, Mohamed, Gamal A, Ibrahim, Sabrin R M, Roh, Eun Joo, Hassan, Ahmed H E
Published in Frontiers in chemistry (2024)
Published in Frontiers in chemistry (2024)
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Exploring the sedative properties of natural molecules from hop cones (Humulus lupulus) as promising natural anxiolytics through GABA receptors and the human serotonin transporter
Belal, Amany, Elballal, Mohammed S., Al-Karmalawy, Ahmed A., Hassan, Ahmed H. E., Roh, Eun Joo, Ghoneim, Mohammed M., Ali, Mohamed A. M., Obaidullah, Ahmad J., Alotaibi, Jawaher M., Shaaban, Salwa, Elanany, Mohamed A.
Published in Frontiers in chemistry (10.07.2024)
Published in Frontiers in chemistry (10.07.2024)
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AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells
Gil, Hyo-Sun, Lee, Jeong-Hun, Farag, Ahmed K., Hassan, Ahmed H. E., Chung, Kyung-Sook, Choi, Jung-Hye, Roh, Eun-Joo, Lee, Kyung-Tae
Published in Cancers (22.11.2021)
Published in Cancers (22.11.2021)
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Small Molecules Incorporating Privileged Amidine Moiety as Potential Hits Combating Antibiotic-Resistant Bacteria
El-Sayed, Selwan M, Ahmed, Samar A, Gulia, Kanika, Lenhard, Justin R, Hassan, Ahmed H E, Farahat, Abdelbasset A
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2023)
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2023)
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