Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
Kormann, Michael S D, Rudolph, Carsten, Hasenpusch, Günther, Aneja, Manish K, Nica, Gabriela, Flemmer, Andreas W, Herber-Jonat, Susanne, Huppmann, Marceline, Mays, Lauren E, Illenyi, Marta, Schams, Andrea, Griese, Matthias, Bittmann, Iris, Handgretinger, Rupert, Hartl, Dominik, Rosenecker, Joseph
Published in Nature biotechnology (01.02.2011)
Published in Nature biotechnology (01.02.2011)
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A Single Methylene Group in Oligoalkylamine-Based Cationic Polymers and Lipids Promotes Enhanced mRNA Delivery
Jarzębińska, Anita, Pasewald, Tamara, Lambrecht, Jana, Mykhaylyk, Olga, Kümmerling, Linda, Beck, Philipp, Hasenpusch, Günther, Rudolph, Carsten, Plank, Christian, Dohmen, Christian
Published in Angewandte Chemie (International ed.) (08.08.2016)
Published in Angewandte Chemie (International ed.) (08.08.2016)
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Self-assembled peptide-poloxamine nanoparticles enable in vitro and in vivo genome restoration for cystic fibrosis
Guan, Shan, Munder, Antje, Hedtfeld, Silke, Braubach, Peter, Glage, Silke, Zhang, Longgui, Lienenklaus, Stefan, Schultze, Anja, Hasenpusch, Günther, Garrels, Wiebke, Stanke, Frauke, Miskey, Csaba, Johler, Sarah M, Kumar, Yadhu, Tümmler, Burkhard, Rudolph, Carsten, Ivics, Zoltan, Rosenecker, Joseph
Published in Nature nanotechnology (01.03.2019)
Published in Nature nanotechnology (01.03.2019)
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Characterization of Tailor-Made Copolymers of Oligo(ethylene glycol) Methyl Ether Methacrylate and N,N-Dimethylaminoethyl Methacrylate as Nonviral Gene Transfer Agents: Influence of Macromolecular Structure on Gene Vector Particle Properties and Transfection Efficiency
Üzgün, Senta, Akdemir, Özgür, Hasenpusch, Günther, Maucksch, Christof, Golas, Monika M, Sander, Bjoern, Stark, Holger, Imker, Rabea, Lutz, Jean-François, Rudolph, Carsten
Published in Biomacromolecules (11.01.2010)
Published in Biomacromolecules (11.01.2010)
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Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA
Schrom, Eva, Huber, Maja, Aneja, Manish, Dohmen, Christian, Emrich, Daniela, Geiger, Johannes, Hasenpusch, Günther, Herrmann-Janson, Annika, Kretzschmann, Verena, Mykhailyk, Olga, Pasewald, Tamara, Oak, Prajakta, Hilgendorff, Anne, Wohlleber, Dirk, Hoymann, Heinz-Gerd, Schaudien, Dirk, Plank, Christian, Rudolph, Carsten, Kubisch-Dohmen, Rebekka
Published in Molecular therapy. Nucleic acids (16.06.2017)
Published in Molecular therapy. Nucleic acids (16.06.2017)
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Journal Article
Aerosolized BC-819 inhibits primary but not secondary lung cancer growth
Hasenpusch, Günther, Pfeifer, Corinna, Aneja, Manish Kumar, Wagner, Kai, Reinhardt, Dietrich, Gilon, Michal, Ohana, Patricia, Hochberg, Avraham, Rudolph, Carsten
Published in PloS one (08.06.2011)
Published in PloS one (08.06.2011)
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Journal Article
Self-assembled peptide–poloxamine nanoparticles enable in vitro and in vivo genome restoration for cystic fibrosis
Guan, Shan, Munder, Antje, Hedtfeld, Silke, Braubach, Peter, Glage, Silke, Zhang, Longgui, Lienenklaus, Stefan, Schultze, Anja, Hasenpusch, Günther, Garrels, Wiebke, Stanke, Frauke, Miskey, Csaba, Johler, Sarah M., Kumar, Yadhu, Tümmler, Burkhard, Rudolph, Carsten, Ivics, Zoltan, Rosenecker, Joseph
Published in Nature nanotechnology (01.03.2019)
Published in Nature nanotechnology (01.03.2019)
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Journal Article
A Single Methylene Group in Oligoalkylamine-Based Cationic Polymers and Lipids Promotes Enhanced mRNA Delivery
Jarzębińska, Anita, Pasewald, Tamara, Lambrecht, Jana, Mykhaylyk, Olga, Kümmerling, Linda, Beck, Philipp, Hasenpusch, Günther, Rudolph, Carsten, Plank, Christian, Dohmen, Christian
Published in Angewandte Chemie (08.08.2016)
Published in Angewandte Chemie (08.08.2016)
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Journal Article
Targeting of the β 2-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo
Elfinger, Markus, Geiger, Johannes, Hasenpusch, Günther, Üzgün, Senta, Sieverling, Nathalie, Aneja, Manish K., Maucksch, Christof, Rudolph, Carsten
Published in Journal of controlled release (01.05.2009)
Published in Journal of controlled release (01.05.2009)
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Journal Article
Transcript-activated collagen matrix as sustained mRNA delivery system for bone regeneration
Badieyan, Zohreh Sadat, Berezhanskyy, Taras, Utzinger, Maximilian, Aneja, Manish Kumar, Emrich, Daniela, Erben, Reinhold, Schüler, Christiane, Altpeter, Philipp, Ferizi, Mehrije, Hasenpusch, Günther, Rudolph, Carsten, Plank, Christian
Published in Journal of controlled release (10.10.2016)
Published in Journal of controlled release (10.10.2016)
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Journal Article
Mucosal IFNλ1 mRNA-based immunomodulation effectively reduces SARS-CoV-2 induced mortality in mice
Macht, Anna, Huang, Yiqi, Reinert, Line S, Grass, Vincent, Lohmer, Kristin, Aristizabal Prada, Elke Tatjana, Babel, Eveline, Semmler, Alexandra, Zhang, Wen, Wegner, Andrea, Lichtenegger-Hartl, Eva, Haas, Sonja, Hasenpusch, Günther, Meyer, Steffen, Paludan, Søren R, Pichlmair, Andreas, Rudolph, Carsten, Langenickel, Thomas
Published in EMBO reports (10.09.2024)
Published in EMBO reports (10.09.2024)
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Journal Article
Chemically Modified Messenger RNA: Modified RNA Application for Treatment of Achilles Tendon Defects
Herbst, Elmar, Imhoff, Florian B, Foehr, Peter, Milz, Stefan, Plank, Christian, Rudolph, Carsten, Hasenpusch, Günther, Geiger, Johannes P, Aneja, Manish K, Groth, Karoline, Vogt, Stephan, Imhoff, Andreas B, Schmitt, Andreas
Published in Tissue engineering. Part A (01.01.2019)
Published in Tissue engineering. Part A (01.01.2019)
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Journal Article
Targeting of the beta(2)-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo
Elfinger, Markus, Geiger, Johannes, Hasenpusch, Günther, Uzgün, Senta, Sieverling, Nathalie, Aneja, Manish K, Maucksch, Christof, Rudolph, Carsten
Published in Journal of controlled release (05.05.2009)
Published in Journal of controlled release (05.05.2009)
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Journal Article
Targeting of the β2-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo
ELFINGER, Markus, GEIGER, Johannes, HASENPUSCH, Günther, UZGÜN, Senta, SIEVERLING, Nathalie, ANEJA, Manish K, MAUCKSCH, Christof, RUDOLPH, Carsten
Published in Journal of controlled release (05.05.2009)
Published in Journal of controlled release (05.05.2009)
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Journal Article
Targeting of the prostacyclin specific IP1 receptor in lungs with molecular conjugates comprising prostaglandin I2 analogues
Geiger, Johannes, Aneja, Manish K, Hasenpusch, Günther, Yüksekdag, Gülnihal, Kummerlöwe, Grit, Luy, Burkhard, Romer, Tina, Rothbauer, Ulrich, Rudolph, Carsten
Published in Biomaterials (01.04.2010)
Published in Biomaterials (01.04.2010)
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Journal Article
Targeting of the prostacyclin specific IP 1 receptor in lungs with molecular conjugates comprising prostaglandin I 2 analogues
Geiger, Johannes, Aneja, Manish K., Hasenpusch, Günther, Yüksekdag, Gülnihal, Kummerlöwe, Grit, Luy, Burkhard, Romer, Tina, Rothbauer, Ulrich, Rudolph, Carsten
Published in Biomaterials (2010)
Published in Biomaterials (2010)
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