Pharmacologic consequences of cholesterol absorption inhibition: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin beta-tigogenin cellobioside (CP-88818; tiqueside)
Harwood, HJ, Chandler, CE, Pellarin, LD, Bangerter, FW, Wilkins, RW, Long, CA, Cosgrove, PG, Malinow, MR, Marzetta, CA, Pettini, JL
Published in Journal of lipid research (01.03.1993)
Published in Journal of lipid research (01.03.1993)
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In vivo regulation of human leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase: increased enzyme protein concentration and catalytic efficiency in human leukemia and lymphoma
Harwood, HJ, Alvarez, IM, Noyes, WD, Stacpoole, PW
Published in Journal of lipid research (01.08.1991)
Published in Journal of lipid research (01.08.1991)
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Journal Article
Lanosterol 14alpha-demethylase (CYP51), NADPH-cytochrome P450 reductase and squalene synthase in spermatogenesis: late spermatids of the rat express proteins needed to synthesize follicular fluid meiosis activating sterol
Majdic, G, Parvinen, M, Bellamine, A, Harwood HJ, Ku, WW, Waterman, MR, Rozman, D
Published in Journal of endocrinology (01.08.2000)
Published in Journal of endocrinology (01.08.2000)
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Journal Article
CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans
Chandler, Charles E, Wilder, Donald E, Pettini, Judith L, Savoy, Yvette E, Petras, Stephen F, Chang, George, Vincent, John, Harwood, Jr, H James
Published in Journal of lipid research (01.10.2003)
Published in Journal of lipid research (01.10.2003)
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Isozyme-nonselective N-Substituted Bipiperidylcarboxamide Acetyl-CoA Carboxylase Inhibitors Reduce Tissue Malonyl-CoA Concentrations, Inhibit Fatty Acid Synthesis, and Increase Fatty Acid Oxidation in Cultured Cells and in Experimental Animals
Harwood, H.James, Petras, Stephen F., Shelly, Lorraine D., Zaccaro, Lawrence M., Perry, David A., Makowski, Michael R., Hargrove, Diane M., Martin, Kelly A., Tracey, W.Ross, Chapman, Justin G., Magee, William P., Dalvie, Deepak K., Soliman, Victor F., Martin, William H., Mularski, Christian J., Eisenbeis, Shane A.
Published in The Journal of biological chemistry (26.09.2003)
Published in The Journal of biological chemistry (26.09.2003)
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Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis
Pandit, J, Danley, D E, Schulte, G K, Mazzalupo, S, Pauly, T A, Hayward, C M, Hamanaka, E S, Thompson, J F, Harwood, Jr, H J
Published in The Journal of biological chemistry (29.09.2000)
Published in The Journal of biological chemistry (29.09.2000)
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Microsomal triglyceride transfer protein (MTP) inhibitors: discovery of clinically active inhibitors using high-throughput screening and parallel synthesis paradigms
Chang, George, Ruggeri, Roger B, Harwood, Jr, H James
Published in Current opinion in drug discovery & development (01.07.2002)
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Published in Current opinion in drug discovery & development (01.07.2002)
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Efficacy, tissue distribution and biliary excretion of methyl (3R,5S)-(E)-3,5-dihydroxy-9,9-diphenyl-6,8-nonadienoate (CP-83101), a hepatoselective inhibitor of HMG-CoA reductase activity in the rat
Harwood, Jr, H J, Silva, M, Chandler, C E, Mikolay, L, Pellarin, L D, Barbacci-Tobin, E, Wint, L T, McCarthy, P A
Published in Biochemical pharmacology (15.09.1990)
Published in Biochemical pharmacology (15.09.1990)
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Development of a noncompetitive, solid phase, bridged biotin-avidin enzyme immunoassay for measurement of human leukocyte microsomal HMG-CoA reductase protein concentration
Harwood, Jr, H J, Alvarez, I M, Greene, Y J, Ness, G C, Stacpoole, P W
Published in Journal of lipid research (01.03.1987)
Published in Journal of lipid research (01.03.1987)
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U.S. Spending For Mental Health And Substance Abuse Treatment, 1991-2001
Mark, Tami L, Coffey, Rosanna M, Vandivort-Warren, Rita, Harwood, Hendrick J, King, Edward C
Published in Health affairs (Millwood, Va.) (01.01.2005)
Published in Health affairs (Millwood, Va.) (01.01.2005)
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Journal Article
Block Copolymer Synthesis by Styrene Polymerization Initiated with Nitroxy-Functionalized Polybutadiene
Kobatake, Seiya, Harwood, H. James, Quirk, Roderic P, Priddy, Duane B
Published in Macromolecules (02.06.1998)
Published in Macromolecules (02.06.1998)
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Effects of l-Triiodothyronine and the Thyromimetic L-94901 on Serum Lipoprotein Levels and Hepatic Low-Density Lipoprotein Receptor, 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase, and Apo A-I Gene Expression
Ness, Gene C, Lopez, Dayami, Chambers, Christopher M, Newsome, William P, Cornelius, Peter, Long, Catherine A, Harwood, H.James
Published in Biochemical pharmacology (01.07.1998)
Published in Biochemical pharmacology (01.07.1998)
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Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase
Harwood, H. James, Petras, Stephen F., Hoover, Dennis J., Mankowski, Dayna C., Soliman, Victor F., Sugarman, Eliot D., Hulin, Bernard, Kwon, Younggil, Gibbs, E. Michael, Mayne, James T., Treadway, Judith L.
Published in Journal of lipid research (01.03.2005)
Published in Journal of lipid research (01.03.2005)
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