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Published in Science advances (01.09.2018)
Published in Science advances (01.09.2018)
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Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro
HOUGHTON, Peter J, GERMAIN, Glen S, HARWOOD, Franklin C, SCHUETZ, John D, STEWART, Clinton F, BUCHDUNGER, Elisabeth, TRAXLER, Peter
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Published in Cancer research (Chicago, Ill.) (01.04.2004)
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Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice
STEWART, Clinton F, LEGGAS, Markos, HARWOOD, Franklin C, HOUGHTON, Peter J, SCHUETZ, John D, PANETTA, John C, CHESHIRE, Pamela J, PETERSON, Jennifer, DAW, Najat, JENKINS, Jesse J, GILBERTSON, Richard, GERMAIN, Glen S
Published in Cancer research (Chicago, Ill.) (15.10.2004)
Published in Cancer research (Chicago, Ill.) (15.10.2004)
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Differential regulation of vascular endothelial growth factor by Akt and mammalian target of rapamycin inhibitors in cell lines derived from childhood solid tumors
Kurmasheva, Raushan T, Harwood, Franklin C, Houghton, Peter J
Published in Molecular cancer therapeutics (01.05.2007)
Published in Molecular cancer therapeutics (01.05.2007)
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Inhibition of Mammalian Target of Rapamycin Activates Apoptosis Signal-regulating Kinase 1 Signaling by Suppressing Protein Phosphatase 5 Activity
Huang, Shile, Shu, Lili, Easton, John, Harwood, Franklin C, Germain, Glen S, Ichijo, Hidenori, Houghton, Peter J
Published in The Journal of biological chemistry (27.08.2004)
Published in The Journal of biological chemistry (27.08.2004)
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Biochemical Correlates of mTOR Inhibition by the Rapamycin Ester CCI-779 and Tumor Growth Inhibition
DUDKIN, Lorina, DILLING, Michael B, CHESHIRE, Pamela J, HARWOOD, Franklin C, HOLLINGSHEAD, Melinda, ARBUCK, Susan G, TRAVIS, Robert, SAUSVILLE, Edward A, HOUGHTON, Peter J
Published in Clinical cancer research (01.06.2001)
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Published in Clinical cancer research (01.06.2001)
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4E-binding Proteins, the Suppressors of Eukaryotic Initiation Factor 4E, Are Down-regulated in Cells with Acquired or Intrinsic Resistance to Rapamycin
Dilling, Michael B., Germain, Glen S., Dudkin, Lorina, Jayaraman, Arun L., Zhang, Xiongwen, Harwood, Franklin C., Houghton, Peter J.
Published in The Journal of biological chemistry (19.04.2002)
Published in The Journal of biological chemistry (19.04.2002)
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Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways
THIMMAIAH, Kuntebommanahalli N, EASTON, John, HUANG, Shile, VEVERKA, Karen A, GERMAIN, Glen S, HARWOOD, Franklin C, HOUGHTON, Peter J
Published in Cancer research (Chicago, Ill.) (15.01.2003)
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Published in Cancer research (Chicago, Ill.) (15.01.2003)
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Synthesis and chemical characterization of N-substituted phenoxazines directed toward reversing vinca alkaloid resistance in multidrug-resistant cancer cells
Thimmaiah, Kuntebommanahalli N, Horton, Julie K, Seshadri, Ramakrishnan, Israel, Mervyn, Houghton, Janet A, Harwood, Franklin C, Houghton, Peter J
Published in Journal of medicinal chemistry (01.09.1992)
Published in Journal of medicinal chemistry (01.09.1992)
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Biochemical pharmacology of 2-chlorodeoxyadenosine in malignant human hematopoietic cell lines and therapeutic effects of 2-bromodeoxyadenosine in drug combinations in mice
AVERY, T. L, REHG, J. E, LUMM, W. C, HARWOOD, F. C, SANTANA, V. M, BLAKLEY, R. L
Published in Cancer research (Chicago, Ill.) (15.09.1989)
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Published in Cancer research (Chicago, Ill.) (15.09.1989)
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Proliferation-dependent and -independent cytotoxicity by antitumor diarylsulfonylureas: Indication of multiple mechanisms of drug action
Sosinski, Janek, Thakar, Jay H., Germain, Glen S., Harwood, Franklin C., Houghton, Peter J.
Published in Biochemical pharmacology (25.05.1993)
Published in Biochemical pharmacology (25.05.1993)
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Pharmacological characterization of N-substituted phenoxazines directed toward reversing Vinca alkaloid resistance in multidrug-resistant cancer cells
HORTON, J. K, THIMMAIAH, K. N, HARWOOD, F. C, KUTTESCH, J. F, HOUGHTON, P. J
Published in Molecular pharmacology (01.09.1993)
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Published in Molecular pharmacology (01.09.1993)
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Proliferation-dependent and -independent cytotoxicity by antitumor diarylsulfonylureas
Sosinski, Janek, Thakar, Jay H., Germain, Glen S., Harwood, Franklin C., Houghton, Peter J.
Published in Biochemical pharmacology (01.04.1993)
Published in Biochemical pharmacology (01.04.1993)
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Cross-resistance to antitumor diarylsulfonylureas and collateral sensitivity to mitochondrial toxins in a human cell line selected for resistance to the antitumor agent N-(5-indanylsulfonyl)-N'-(4-chlorophenyl)urea
SOSINSKI, J, THAKAR, J. H, GERMAIN, G. S, DIAS, P, HARWOOD, F. C, KUTESCH, J. F, HOUGHTON, P. J
Published in Molecular pharmacology (01.05.1994)
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Published in Molecular pharmacology (01.05.1994)
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