Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
Wagner, Stefanie, Sommer, Roman, Hinsberger, Stefan, Lu, Cenbin, Hartmann, Rolf W, Empting, Martin, Titz, Alexander
Published in Journal of medicinal chemistry (14.07.2016)
Published in Journal of medicinal chemistry (14.07.2016)
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Journal Article
Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa
Sommer, Roman, Wagner, Stefanie, Rox, Katharina, Varrot, Annabelle, Hauck, Dirk, Wamhoff, Eike-Christian, Schreiber, Janine, Ryckmans, Thomas, Brunner, Thomas, Rademacher, Christoph, Hartmann, Rolf W, Brönstrup, Mark, Imberty, Anne, Titz, Alexander
Published in Journal of the American Chemical Society (21.02.2018)
Published in Journal of the American Chemical Society (21.02.2018)
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Journal Article
Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure–Activity Relationship Study of C‑Glycosidic LecB Inhibitors
Sommer, Roman, Rox, Katharina, Wagner, Stefanie, Hauck, Dirk, Henrikus, Sarah S, Newsad, Shelby, Arnold, Tatjana, Ryckmans, Thomas, Brönstrup, Mark, Imberty, Anne, Varrot, Annabelle, Hartmann, Rolf W, Titz, Alexander
Published in Journal of medicinal chemistry (24.10.2019)
Published in Journal of medicinal chemistry (24.10.2019)
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Journal Article
Antibiotic-free nanotherapeutics: Ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors
Nafee, Noha, Husari, Ayman, Maurer, Christine K., Lu, Cenbin, de Rossi, Chiara, Steinbach, Anke, Hartmann, Rolf W., Lehr, Claus-Michael, Schneider, Marc
Published in Journal of controlled release (28.10.2014)
Published in Journal of controlled release (28.10.2014)
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Journal Article
Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors
Schmitt, Christian, Kail, Dagmar, Mariano, Marica, Empting, Martin, Weber, Nadja, Paul, Tamara, Hartmann, Rolf W, Engel, Matthias
Published in PloS one (27.03.2014)
Published in PloS one (27.03.2014)
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Journal Article
Overcoming the Unexpected Functional Inversion of a PqsR Antagonist in Pseudomonas aeruginosa: An In Vivo Potent Antivirulence Agent Targeting pqs Quorum Sensing
Lu, Cenbin, Maurer, Christine K., Kirsch, Benjamin, Steinbach, Anke, Hartmann, Rolf W.
Published in Angewandte Chemie International Edition (20.01.2014)
Published in Angewandte Chemie International Edition (20.01.2014)
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Journal Article
Recent progress in pharmaceutical therapies for castration-resistant prostate cancer
Yin, Lina, Hu, Qingzhong, Hartmann, Rolf W
Published in International Journal of Molecular Sciences (04.07.2013)
Published in International Journal of Molecular Sciences (04.07.2013)
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Book Review
2‑Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action
Bestgen, Benoît, Kufareva, Irina, Seetoh, Weiguang, Abell, Chris, Hartmann, Rolf W, Abagyan, Ruben, Le Borgne, Marc, Filhol, Odile, Cochet, Claude, Lomberget, Thierry, Engel, Matthias
Published in Journal of medicinal chemistry (28.02.2019)
Published in Journal of medicinal chemistry (28.02.2019)
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Journal Article
Optimization of Hydroxybenzothiazoles as Novel Potent and Selective Inhibitors of 17β-HSD1
Spadaro, Alessandro, Frotscher, Martin, Hartmann, Rolf W
Published in Journal of medicinal chemistry (08.03.2012)
Published in Journal of medicinal chemistry (08.03.2012)
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Journal Article
Crystalline Sponges as a sensitive and fast method for metabolite identification: Application to gemfibrozil and its phase I and II metabolites
Rosenberger, Lara, von Essen, Carolina, Khutia, Anupam, Kuehn, Clemens, Urbahns, Klaus, Georgi, Katrin, Hartmann, Rolf W, Badolo, Lassina
Published in Drug metabolism and disposition (01.07.2020)
Published in Drug metabolism and disposition (01.07.2020)
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Journal Article
Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections
Ho, Duy‐Khiet, Murgia, Xabier, De Rossi, Chiara, Christmann, Rebekka, Hüfner de Mello Martins, Antonio G., Koch, Marcus, Andreas, Anastasia, Herrmann, Jennifer, Müller, Rolf, Empting, Martin, Hartmann, Rolf W., Desmaele, Didier, Loretz, Brigitta, Couvreur, Patrick, Lehr, Claus‐Michael
Published in Angewandte Chemie International Edition (22.06.2020)
Published in Angewandte Chemie International Edition (22.06.2020)
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Journal Article
In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor Treatment
Allegretta, Giuseppe, Maurer, Christine K, Eberhard, Jens, Maura, Damien, Hartmann, Rolf W, Rahme, Laurence, Empting, Martin
Published in Frontiers in microbiology (24.05.2017)
Published in Frontiers in microbiology (24.05.2017)
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Journal Article
2‑Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site
Bestgen, Benoît, Krimm, Isabelle, Kufareva, Irina, Kamal, Ahmed Ashraf Moustafa, Seetoh, Wei-Guang, Abell, Chris, Hartmann, Rolf W, Abagyan, Ruben, Cochet, Claude, Le Borgne, Marc, Engel, Matthias, Lomberget, Thierry
Published in Journal of medicinal chemistry (28.02.2019)
Published in Journal of medicinal chemistry (28.02.2019)
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