Molecular chaperones in targeting misfolded proteins for ubiquitin‐dependent degradation
Kriegenburg, Franziska, Ellgaard, Lars, Hartmann‐Petersen, Rasmus
Published in The FEBS journal (01.02.2012)
Published in The FEBS journal (01.02.2012)
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Journal Article
Toward mechanistic models for genotype–phenotype correlations in phenylketonuria using protein stability calculations
Scheller, Rasmus, Stein, Amelie, Nielsen, Sofie V., Marin, Frederikke I., Gerdes, Anne‐Marie, Marco, Miriam, Papaleo, Elena, Lindorff‐Larsen, Kresten, Hartmann‐Petersen, Rasmus
Published in Human mutation (01.04.2019)
Published in Human mutation (01.04.2019)
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Journal Article
Phosphorylation of Schizosaccharomyces pombe Dss1 mediates direct binding to the ubiquitin‐ligase Dma1 in vitro
Jacobsen, Nina L., Bloch, Magnus, Millard, Peter S., Ruidiaz, Sarah F., Elsborg, Jonas D., Boomsma, Wouter, Hendus‐Altenburger, Ruth, Hartmann‐Petersen, Rasmus, Kragelund, Birthe B.
Published in Protein science (01.09.2023)
Published in Protein science (01.09.2023)
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Journal Article
Discovering functionally important sites in proteins
Cagiada, Matteo, Bottaro, Sandro, Lindemose, Søren, Schenstrøm, Signe M., Stein, Amelie, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten
Published in Nature communications (13.07.2023)
Published in Nature communications (13.07.2023)
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Journal Article
Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition
Nielsen, Sofie V, Hartmann-Petersen, Rasmus, Stein, Amelie, Lindorff-Larsen, Kresten
Published in PLoS genetics (22.04.2021)
Published in PLoS genetics (22.04.2021)
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Journal Article
Conserved degronome features governing quality control associated proteolysis
Mashahreh, Bayan, Armony, Shir, Johansson, Kristoffer Enøe, Chappleboim, Alon, Friedman, Nir, Gardner, Richard G., Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten, Ravid, Tommer
Published in Nature communications (08.12.2022)
Published in Nature communications (08.12.2022)
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Journal Article
A comprehensive map of human glucokinase variant activity
Gersing, Sarah, Cagiada, Matteo, Gebbia, Marinella, Gjesing, Anette P, Coté, Atina G, Seesankar, Gireesh, Li, Roujia, Tabet, Daniel, Weile, Jochen, Stein, Amelie, Gloyn, Anna L, Hansen, Torben, Roth, Frederick P, Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus
Published in Genome Biology (26.04.2023)
Published in Genome Biology (26.04.2023)
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Journal Article
Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation
Clausen, Lene, Stein, Amelie, Grønbæk-Thygesen, Martin, Nygaard, Lasse, Søltoft, Cecilie L, Nielsen, Sofie V, Lisby, Michael, Ravid, Tommer, Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus
Published in PLoS genetics (01.11.2020)
Published in PLoS genetics (01.11.2020)
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Journal Article
Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants
Grønbæk-Thygesen, Martin, Voutsinos, Vasileios, Johansson, Kristoffer E., Schulze, Thea K., Cagiada, Matteo, Pedersen, Line, Clausen, Lene, Nariya, Snehal, Powell, Rachel L., Stein, Amelie, Fowler, Douglas M., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus
Published in Nature communications (13.05.2024)
Published in Nature communications (13.05.2024)
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Journal Article
A context-dependent and disordered ubiquitin-binding motif
Dreier, Jesper E., Prestel, Andreas, Martins, João M., Brøndum, Sebastian S., Nielsen, Olaf, Garbers, Anna E., Suga, Hiroaki, Boomsma, Wouter, Rogers, Joseph M., Hartmann-Petersen, Rasmus, Kragelund, Birthe B.
Published in Cellular and molecular life sciences : CMLS (01.09.2022)
Published in Cellular and molecular life sciences : CMLS (01.09.2022)
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Journal Article
Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations
Nielsen, Sofie V, Stein, Amelie, Dinitzen, Alexander B, Papaleo, Elena, Tatham, Michael H, Poulsen, Esben G, Kassem, Maher M, Rasmussen, Lene J, Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus
Published in PLoS genetics (19.04.2017)
Published in PLoS genetics (19.04.2017)
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Journal Article
Mapping the degradation pathway of a disease-linked aspartoacylase variant
Gersing, Sarah K, Wang, Yong, Grønbæk-Thygesen, Martin, Kampmeyer, Caroline, Clausen, Lene, Willemoës, Martin, Andréasson, Claes, Stein, Amelie, Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus
Published in PLoS genetics (29.04.2021)
Published in PLoS genetics (29.04.2021)
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Journal Article
A mutational atlas for Parkin proteostasis
Clausen, Lene, Voutsinos, Vasileios, Cagiada, Matteo, Johansson, Kristoffer E., Grønbæk-Thygesen, Martin, Nariya, Snehal, Powell, Rachel L., Have, Magnus K. N., Oestergaard, Vibe H., Stein, Amelie, Fowler, Douglas M., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus
Published in Nature communications (20.02.2024)
Published in Nature communications (20.02.2024)
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Journal Article
Dss1 Is a 26S Proteasome Ubiquitin Receptor
Paraskevopoulos, Konstantinos, Kriegenburg, Franziska, Tatham, Michael H., Rösner, Heike I., Medina, Bethan, Larsen, Ida B., Brandstrup, Rikke, Hardwick, Kevin G., Hay, Ronald T., Kragelund, Birthe B., Hartmann-Petersen, Rasmus, Gordon, Colin
Published in Molecular cell (06.11.2014)
Published in Molecular cell (06.11.2014)
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Journal Article
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome
Abildgaard, Amanda B, Stein, Amelie, Nielsen, Sofie V, Schultz-Knudsen, Katrine, Papaleo, Elena, Shrikhande, Amruta, Hoffmann, Eva R, Bernstein, Inge, Gerdes, Anne-Marie, Takahashi, Masanobu, Ishioka, Chikashi, Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus
Published in eLife (07.11.2019)
Published in eLife (07.11.2019)
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