Trametinib-Resistant Melanoma Cells Displaying MITFhigh/NGFRlow/IL-8low Phenotype Are Highly Responsive to Alternating Periods of Drug Withdrawal and Drug Rechallenge
Koziej, Paulina, Kluszczynska, Katarzyna, Hartman, Mariusz L., Czyz, Malgorzata
Published in International journal of molecular sciences (26.04.2023)
Published in International journal of molecular sciences (26.04.2023)
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Journal Article
Physiologically Relevant Oxygen Concentration (6% O 2 ) as an Important Component of the Microenvironment Impacting Melanoma Phenotype and Melanoma Response to Targeted Therapeutics In Vitro
Osrodek, Marta, Hartman, Mariusz L, Czyz, Malgorzata
Published in International journal of molecular sciences (27.08.2019)
Published in International journal of molecular sciences (27.08.2019)
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Journal Article
Dissecting Mechanisms of Melanoma Resistance to BRAF and MEK Inhibitors Revealed Genetic and Non-Genetic Patient- and Drug-Specific Alterations and Remarkable Phenotypic Plasticity
Hartman, Mariusz L, Sztiller-Sikorska, Malgorzata, Gajos-Michniewicz, Anna, Czyz, Malgorzata
Published in Cells (Basel, Switzerland) (07.01.2020)
Published in Cells (Basel, Switzerland) (07.01.2020)
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Journal Article
17-Aminogeldanamycin Inhibits Constitutive Nuclear Factor-Kappa B (NF-κB) Activity in Patient-Derived Melanoma Cell Lines
Hartman, Mariusz L, Rogut, Magdalena, Mielczarek-Lewandowska, Aleksandra, Wozniak, Michal, Czyz, Malgorzata
Published in International journal of molecular sciences (26.05.2020)
Published in International journal of molecular sciences (26.05.2020)
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Journal Article
Pro-Apoptotic Activity of MCL-1 Inhibitor in Trametinib-Resistant Melanoma Cells Depends on Their Phenotypes and Is Modulated by Reversible Alterations Induced by Trametinib Withdrawal
Hartman, Mariusz L, Koziej, Paulina, Kluszczyńska, Katarzyna, Czyz, Małgorzata
Published in Cancers (29.09.2023)
Published in Cancers (29.09.2023)
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Journal Article
MITF in melanoma: mechanisms behind its expression and activity
Hartman, Mariusz L, Czyz, Malgorzata
Published in Cellular and molecular life sciences : CMLS (01.04.2015)
Published in Cellular and molecular life sciences : CMLS (01.04.2015)
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Journal Article
Gene expression profiling identifies microphthalmia-associated transcription factor (MITF) and Dickkopf-1 (DKK1) as regulators of microenvironment-driven alterations in melanoma phenotype
Hartman, Mariusz L, Talar, Beata, Noman, Muhammad Zaeem, Gajos-Michniewicz, Anna, Chouaib, Salem, Czyz, Malgorzata
Published in PloS one (14.04.2014)
Published in PloS one (14.04.2014)
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Journal Article
Exogenous growth factors bFGF, EGF and HGF do not influence viability and phenotype of V600EBRAF melanoma cells and their response to vemurafenib and trametinib in vitro
Zalesna, Izabela, Osrodek, Marta, Hartman, Mariusz L, Rozanski, Michal, Sztiller-Sikorska, Malgorzata, Niewinna, Karolina, Nejc, Dariusz, Czyz, Malgorzata
Published in PloS one (2017)
Published in PloS one (2017)
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Journal Article
Pro-Survival Role of MITF in Melanoma
Hartman, Mariusz L., Czyz, Malgorzata
Published in Journal of investigative dermatology (01.02.2015)
Published in Journal of investigative dermatology (01.02.2015)
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Journal Article
Inhibitors of HSP90 in melanoma
Mielczarek-Lewandowska, Aleksandra, Hartman, Mariusz L., Czyz, Malgorzata
Published in Apoptosis (London) (01.02.2020)
Published in Apoptosis (London) (01.02.2020)
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Journal Article
Trametinib-Resistant Melanoma Cells Displaying MITF[sup.high]/NGFR[sup.low]/IL-8[sup.low] Phenotype Are Highly Responsive to Alternating Periods of Drug Withdrawal and Drug Rechallenge
Koziej, Paulina, Kluszczynska, Katarzyna, Hartman, Mariusz L, Czyz, Malgorzata
Published in International journal of molecular sciences (01.04.2023)
Published in International journal of molecular sciences (01.04.2023)
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Journal Article