Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism
Hartleben, Goetz, Schorpp, Kenji, Kwon, Yun, Betz, Barbara, Tsokanos, Foivos‐Filippos, Dantes, Zahra, Schäfer, Arlett, Rothenaigner, Ina, Monroy Kuhn, José Manuel, Morigny, Pauline, Mehr, Lisa, Lin, Sean, Seitz, Susanne, Tokarz, Janina, Artati, Anna, Adamsky, Jerzy, Plettenburg, Oliver, Lutter, Dominik, Irmler, Martin, Beckers, Johannes, Reichert, Maximilian, Hadian, Kamyar, Zeigerer, Anja, Herzig, Stephan, Berriel Diaz, Mauricio
Published in EMBO molecular medicine (09.04.2021)
Published in EMBO molecular medicine (09.04.2021)
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Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2‐Dependent Mitotic Cell Death
Rios Garcia, Marcos, Meissburger, Bettina, Chan, Jessica, Guia, Roldan M., Mattijssen, Frits, Roessler, Stephanie, Birkenfeld, Andreas L., Raschzok, Nathanael, Riols, Fabien, Tokarz, Janina, Giroud, Maude, Gil Lozano, Manuel, Hartleben, Goetz, Nawroth, Peter, Haid, Mark, López, Miguel, Herzig, Stephan, Berriel Diaz, Mauricio
Published in Advanced science (01.10.2022)
Published in Advanced science (01.10.2022)
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Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
Gödel, Markus, Hartleben, Björn, Herbach, Nadja, Liu, Shuya, Zschiedrich, Stefan, Lu, Shun, Debreczeni-Mór, Andrea, Lindenmeyer, Maja T, Rastaldi, Maria-Pia, Hartleben, Götz, Wiech, Thorsten, Fornoni, Alessia, Nelson, Robert G, Kretzler, Matthias, Wanke, Rüdiger, Pavenstädt, Hermann, Kerjaschki, Dontscho, Cohen, Clemens D, Hall, Michael N, Rüegg, Markus A, Inoki, Ken, Walz, Gerd, Huber, Tobias B
Published in The Journal of clinical investigation (01.06.2011)
Published in The Journal of clinical investigation (01.06.2011)
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A distinct metabolic state arises during the emergence of 2‐cell‐like cells
Rodriguez‐Terrones, Diego, Hartleben, Götz, Gaume, Xavier, Eid, André, Guthmann, Manuel, Iturbide, Ane, Torres‐Padilla, Maria‐Elena
Published in EMBO reports (07.01.2020)
Published in EMBO reports (07.01.2020)
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Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice
Missios, Pavlos, Zhou, Yuan, Guachalla, Luis Miguel, von Figura, Guido, Wegner, Andre, Chakkarappan, Sundaram Reddy, Binz, Tina, Gompf, Anne, Hartleben, Götz, Burkhalter, Martin D, Wulff, Veronika, Günes, Cagatay, Sattler, Rui Wang, Song, Zhangfa, Illig, Thomas, Klaus, Susanne, Böhm, Bernhard O, Wenz, Tina, Hiller, Karsten, Rudolph, K Lenhard
Published in Nature communications (18.09.2014)
Published in Nature communications (18.09.2014)
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Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice
Görgülü, Kivanc, Diakopoulos, Kalliope N., Ai, Jiaoyu, Schoeps, Benjamin, Kabacaoglu, Derya, Karpathaki, Angeliki-Faidra, Ciecielski, Katrin J., Kaya-Aksoy, Ezgi, Ruess, Dietrich A., Berninger, Alexandra, Kowalska, Marlena, Stevanovic, Marija, Wörmann, Sonja M., Wartmann, Thomas, Zhao, Yue, Halangk, Walter, Voronina, Svetlana, Tepikin, Alexey, Schlitter, Anna Melissa, Steiger, Katja, Artati, Anna, Adamski, Jerzy, Aichler, Michaela, Walch, Axel, Jastroch, Martin, Hartleben, Götz, Mantzoros, Christos S., Weichert, Wilko, Schmid, Roland M., Herzig, Stephan, Krüger, Achim, Sainz, Bruno, Lesina, Marina, Algül, Hana
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2019)
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A p300 and SIRT1 Regulated Acetylation Switch of C/EBPα Controls Mitochondrial Function
Zaini, Mohamad A., Müller, Christine, de Jong, Tristan V., Ackermann, Tobias, Hartleben, Götz, Kortman, Gertrud, Gührs, Karl-Heinz, Fusetti, Fabrizia, Krämer, Oliver H., Guryev, Victor, Calkhoven, Cornelis F.
Published in Cell reports (Cambridge) (09.01.2018)
Published in Cell reports (Cambridge) (09.01.2018)
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Tuberous sclerosis complex is required for tumor maintenance in MYC‐driven Burkitt's lymphoma
Hartleben, Götz, Müller, Christine, Krämer, Andreas, Schimmel, Heiko, Zidek, Laura M, Dornblut, Carsten, Winkler, René, Eichwald, Sabrina, Kortman, Gertrud, Kosan, Christian, Kluiver, Joost, Petersen, Iver, van den Berg, Anke, Wang, Zhao‐Qi, Calkhoven, Cornelis F
Published in The EMBO journal (02.11.2018)
Published in The EMBO journal (02.11.2018)
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Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice
Zidek, Laura M, Ackermann, Tobias, Hartleben, Götz, Eichwald, Sabrina, Kortman, Gertrud, Kiehntopf, Michael, Leutz, Achim, Sonenberg, Nahum, Wang, Zhao-Qi, von Maltzahn, Julia, Müller, Christine, Calkhoven, Cornelis F
Published in EMBO reports (01.08.2015)
Published in EMBO reports (01.08.2015)
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Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity
Seitz, Susanne, Kwon, Yun, Hartleben, Götz, Jülg, Julia, Sekar, Revathi, Krahmer, Natalie, Najafi, Bahar, Loft, Anne, Gancheva, Sofiya, Stemmer, Kerstin, Feuchtinger, Annette, Hrabe de Angelis, Martin, Müller, Timo D, Mann, Matthias, Blüher, Matthias, Roden, Michael, Berriel Diaz, Mauricio, Behrends, Christian, Gilleron, Jerome, Herzig, Stephan, Zeigerer, Anja
Published in Nature metabolism (01.10.2019)
Published in Nature metabolism (01.10.2019)
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