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Published in Nature (London) (01.05.2018)
Published in Nature (London) (01.05.2018)
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Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
De Bock, Katrien, Moons, Lieve, Lafuste, Peggy, Tjwa, Marc, Gnaiger, Erich, Fraisl, Peter, Pugh, Chris, Deroose, Christophe, Grosfeld, Alexandra, Wijeyekoon, Bhathiya, Harten, Sarah K, Van Noten, Pieter, Carmeliet, Peter, Van Hecke, Paul, Vandendriessche, Thierry, Aragonés, Julián, Silasi-Mansat, Robert, Dewerchin, Mieke, Schneider, Martin, Mortelmans, Luc, Buyse, Johan, Diez-Juan, Antonio, Willam, Carsten, Maxwell, Patrick, Van Geyte, Katie, Gorus, Frans, Zacchigna, Serena, Dirkx, Ruud, Nuyts, Johan, Jordan, Benedicte, Salmon, Phil, Harris, Robert A, Lemieux, Hélène, Van Veldhoven, Paul, Bishop, Tammie, Ratcliffe, Peter, Jeoung, Nam Ho, Baes, Myriam, Hespel, Peter, Schuit, Frans, Lupu, Florea, Dresselaers, Tom, Mazzone, Massimiliano, Lambrechts, Diether, Gallez, Bernard, Sluse, Francis, Navet, Rachel
Published in Nature genetics (01.02.2008)
Published in Nature genetics (01.02.2008)
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Prolyl hydroxylase domain inhibitors: a route to HIF activation and neuroprotection
Harten, Sarah K, Ashcroft, Margaret, Maxwell, Patrick H
Published in Antioxidants & redox signaling (15.02.2010)
Published in Antioxidants & redox signaling (15.02.2010)
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Regulation of E-cadherin expression by VHL and hypoxia-inducible factor
Esteban, Miguel A, Tran, Maxine G B, Harten, Sarah K, Hill, Peter, Castellanos, Maria C, Chandra, Ashish, Raval, Raju, O'brien, Tim S, Maxwell, Patrick H
Published in Cancer research (Chicago, Ill.) (01.04.2006)
Published in Cancer research (Chicago, Ill.) (01.04.2006)
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The metastasis suppressor RARRES3 as an endogenous inhibitor of the immunoproteasome expression in breast cancer cells
Anderson, Alison M, Kalimutho, Murugan, Harten, Sarah, Nanayakkara, Devathri M, Khanna, Kum Kum, Ragan, Mark A
Published in Scientific reports (04.01.2017)
Published in Scientific reports (04.01.2017)
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Enhanced dependency of KRAS‐mutant colorectal cancer cells on RAD51‐dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae
Kalimutho, Murugan, Bain, Amanda L., Mukherjee, Bipasha, Nag, Purba, Nanayakkara, Devathri M., Harten, Sarah K., Harris, Janelle L., Subramanian, Goutham N., Sinha, Debottam, Shirasawa, Senji, Srihari, Sriganesh, Burma, Sandeep, Khanna, Kum Kum
Published in Molecular oncology (01.05.2017)
Published in Molecular oncology (01.05.2017)
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VHL Inactivation Induces HEF1 and Aurora Kinase A
JIANYONG XU, HUAPENG LI, ESTEBAN, Miguel A, BO WANG, YAN XU, JIAYIN YANG, XIAOFEI ZHANG, HARTEN, Sarah K, SHUKLA, Deepa, MAXWELL, Patrick H, DUANQING PEI
Published in Journal of the American Society of Nephrology (01.12.2010)
Published in Journal of the American Society of Nephrology (01.12.2010)
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Cezanne Regulates Inflammatory Responses to Hypoxia in Endothelial Cells by Targeting TRAF6 for Deubiquitination
Luong, Le A, Fragiadaki, Maria, Smith, Jennifer, Boyle, Joseph, Lutz, Jens, Dean, Jonathan L.E, Harten, Sarah, Ashcroft, Margaret, Walmsley, Sarah R, Haskard, Dorian O, Maxwell, Patrick H, Walczak, Henning, Pusey, Charles, Evans, Paul C
Published in Circulation research (07.06.2013)
Published in Circulation research (07.06.2013)
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Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice
Cantley, James, Selman, Colin, Shukla, Deepa, Abramov, Andrey Y, Forstreuter, Frauke, Esteban, Miguel A, Claret, Marc, Lingard, Steven J, Clements, Melanie, Harten, Sarah K, Asare-Anane, Henry, Batterham, Rachel L, Herrera, Pedro L, Persaud, Shanta J, Duchen, Michael R, Maxwell, Patrick H, Withers, Dominic J
Published in The Journal of clinical investigation (01.01.2009)
Published in The Journal of clinical investigation (01.01.2009)
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Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin
Harten, Sarah K, Shukla, Deepa, Barod, Ravi, Hergovich, Alexander, Balda, Maria S, Matter, Karl, Esteban, Miguel A, Maxwell, Patrick H
Published in Molecular biology of the cell (01.02.2009)
Published in Molecular biology of the cell (01.02.2009)
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HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia
Mowat, Freya M, Luhmann, Ulrich F O, Smith, Alexander J, Lange, Clemens, Duran, Yanai, Harten, Sarah, Shukla, Deepa, Maxwell, Patrick H, Ali, Robin R, Bainbridge, James W B
Published in PloS one (14.06.2010)
Published in PloS one (14.06.2010)
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first mouse mutants of D14Abb1e (Fam208a) show that it is critical for early development
Harten, Sarah K, Bruxner, Timothy J, Bharti, Vandhana, Blewitt, Marnie, Nguyen, Thi-My-Tam, Whitelaw, Emma, Epp, Trevor
Published in Mammalian genome (01.08.2014)
Published in Mammalian genome (01.08.2014)
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The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers
Harten, Sarah K, Oey, Harald, Bourke, Lauren M, Bharti, Vandhana, Isbel, Luke, Daxinger, Lucia, Faou, Pierre, Robertson, Neil, Matthews, Jacqueline M, Whitelaw, Emma
Published in BMC biology (26.03.2015)
Published in BMC biology (26.03.2015)
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Identification of novel hypomorphic and null mutations in Klf1 derived from a genetic screen for modifiers of α-globin transgene variegation
Sorolla, Anabel, Tallack, Michael R., Oey, Harald, Harten, Sarah K., Daxinger, Lucia Clemens, Magor, Graham W., Combes, Alex N., Ilsley, Melissa, Whitelaw, Emma, Perkins, Andrew C.
Published in Genomics (San Diego, Calif.) (01.02.2015)
Published in Genomics (San Diego, Calif.) (01.02.2015)
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Enhanced dependency of KRAS ‐mutant colorectal cancer cells on RAD 51‐dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae
Kalimutho, Murugan, Bain, Amanda L., Mukherjee, Bipasha, Nag, Purba, Nanayakkara, Devathri M., Harten, Sarah K., Harris, Janelle L., Subramanian, Goutham N., Sinha, Debottam, Shirasawa, Senji, Srihari, Sriganesh, Burma, Sandeep, Khanna, Kum Kum
Published in Molecular oncology (01.05.2017)
Published in Molecular oncology (01.05.2017)
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ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse
Daxinger, Lucia, Harten, Sarah K, Oey, Harald, Epp, Trevor, Isbel, Luke, Huang, Edward, Whitelaw, Nadia, Apedaile, Anwyn, Sorolla, Anabel, Yong, Joan, Bharti, Vandhana, Sutton, Joanne, Ashe, Alyson, Pang, Zhenyi, Wallace, Nathan, Gerhardt, Daniel J, Blewitt, Marnie E, Jeddeloh, Jeffrey A, Whitelaw, Emma
Published in Genome biology (01.01.2013)
Published in Genome biology (01.01.2013)
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No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations
Youngson, Neil A., Epp, Trevor, Roberts, Amity R., Daxinger, Lucia, Ashe, Alyson, Huang, Edward, Lester, Krystal L., Harten, Sarah K., Kay, Graham F., Cox, Timothy, Matthews, Jacqueline M., Chong, Suyinn, Whitelaw, Emma
Published in Mammalian genome (01.06.2013)
Published in Mammalian genome (01.06.2013)
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