Mechanotransduction and Stiffness-Sensing: Mechanisms and Opportunities to Control Multiple Molecular Aspects of Cell Phenotype as a Design Cornerstone of Cell-Instructive Biomaterials for Articular Cartilage Repair
Selig, Mischa, Lauer, Jasmin C, Hart, Melanie L, Rolauffs, Bernd
Published in International journal of molecular sciences (29.07.2020)
Published in International journal of molecular sciences (29.07.2020)
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An Evidence-Based Systematic Review of Human Knee Post-Traumatic Osteoarthritis (PTOA): Timeline of Clinical Presentation and Disease Markers, Comparison of Knee Joint PTOA Models and Early Disease Implications
Khella, Christine M, Asgarian, Rojiar, Horvath, Judith M, Rolauffs, Bernd, Hart, Melanie L
Published in International journal of molecular sciences (17.02.2021)
Published in International journal of molecular sciences (17.02.2021)
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Journal Article
Articular Chondrocyte Phenotype Regulation through the Cytoskeleton and the Signaling Processes That Originate from or Converge on the Cytoskeleton: Towards a Novel Understanding of the Intersection between Actin Dynamics and Chondrogenic Function
Lauer, Jasmin C, Selig, Mischa, Hart, Melanie L, Kurz, Bodo, Rolauffs, Bernd
Published in International journal of molecular sciences (23.03.2021)
Published in International journal of molecular sciences (23.03.2021)
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Articular Cartilage—From Basic Science Structural Imaging to Non-Invasive Clinical Quantitative Molecular Functional Information for AI Classification and Prediction
Kurz, Bodo, Lange, Thomas, Voelker, Marita, Hart, Melanie L, Rolauffs, Bernd
Published in International journal of molecular sciences (01.10.2023)
Published in International journal of molecular sciences (01.10.2023)
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Journal Article
Anti-Inflammatory Therapeutic Approaches to Prevent or Delay Post-Traumatic Osteoarthritis (PTOA) of the Knee Joint with a Focus on Sustained Delivery Approaches
Khella, Christine M, Horvath, Judith M, Asgarian, Rojiar, Rolauffs, Bernd, Hart, Melanie L
Published in International journal of molecular sciences (27.07.2021)
Published in International journal of molecular sciences (27.07.2021)
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Journal Article
Prediction of six macrophage phenotypes and their IL-10 content based on single-cell morphology using artificial intelligence
Selig, Mischa, Poehlman, Logan, Lang, Nils C, Völker, Marita, Rolauffs, Bernd, Hart, Melanie L
Published in Frontiers in immunology (04.01.2024)
Published in Frontiers in immunology (04.01.2024)
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Stress urinary incontinence animal models as a tool to study cell-based regenerative therapies targeting the urethral sphincter
Herrera-Imbroda, Bernardo, Lara, María F., Izeta, Ander, Sievert, Karl-Dietrich, Hart, Melanie L.
Published in Advanced drug delivery reviews (01.03.2015)
Published in Advanced drug delivery reviews (01.03.2015)
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Journal Article
Engineering the geometrical shape of mesenchymal stromal cells through defined cyclic stretch regimens
Walters, Brandan, Uynuk-Ool, Tatiana, Rothdiener, Miriam, Palm, Julian, Hart, Melanie L., Stegemann, Jan P., Rolauffs, Bernd
Published in Scientific reports (26.07.2017)
Published in Scientific reports (26.07.2017)
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Journal Article
SP1-Dependent Induction of CD39 Facilitates Hepatic Ischemic Preconditioning
Hart, Melanie L, Gorzolla, Iris C, Schittenhelm, Jens, Robson, Simon C, Eltzschig, Holger K
Published in The Journal of immunology (1950) (01.04.2010)
Published in The Journal of immunology (1950) (01.04.2010)
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Human Placenta-Derived CD146-Positive Mesenchymal Stromal Cells Display a Distinct Osteogenic Differentiation Potential
Ulrich, Christine, Abruzzese, Tanja, Maerz, Jan K, Ruh, Manuel, Amend, Bastian, Benz, Karin, Rolauffs, Bernd, Abele, Harald, Hart, Melanie L, Aicher, Wilhelm K
Published in Stem cells and development (01.07.2015)
Published in Stem cells and development (01.07.2015)
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CD39/Ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury
KÖHLER, David, ECKLE, Tobias, FAIGLE, Marion, GRENZ, Almut, MITTELBRONN, Michel, LAUCHER, Stefanie, HART, Melanie L, ROBSON, Simon C, MÜLLER, Christa E, ELTZSCHIG, Holger K
Published in Circulation (New York, N.Y.) (16.10.2007)
Published in Circulation (New York, N.Y.) (16.10.2007)
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Journal Article
The geometrical shape of mesenchymal stromal cells measured by quantitative shape descriptors is determined by the stiffness of the biomaterial and by cyclic tensile forces
Uynuk‐Ool, Tatiana, Rothdiener, Miriam, Walters, Brandan, Hegemann, Miriam, Palm, Julian, Nguyen, Phong, Seeger, Tanja, Stöckle, Ulrich, Stegemann, Jan P., Aicher, Wilhelm K., Kurz, Bodo, Hart, Melanie L., Klein, Gerd, Rolauffs, Bernd
Published in Journal of tissue engineering and regenerative medicine (01.12.2017)
Published in Journal of tissue engineering and regenerative medicine (01.12.2017)
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Journal Article
Characterization and In Vitro Cytotoxicity Safety Screening of Fractionated Organosolv Lignin on Diverse Primary Human Cell Types Commonly Used in Tissue Engineering
Menima-Medzogo, Jules A, Walz, Kathrin, Lauer, Jasmin C, Sivasankarapillai, Gopakumar, Gleuwitz, F Robert, Rolauffs, Bernd, Laborie, Marie-Pierre, Hart, Melanie L
Published in Biology (Basel, Switzerland) (30.04.2022)
Published in Biology (Basel, Switzerland) (30.04.2022)
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Journal Article
Effect of Vancomycin, Gentamicin and Clindamycin on Cartilage Cells In Vitro
Mayr, Hermann O, Regenbrecht, Nina, Mayr, Moritz Florian, Riedel, Bianca, Hart, Melanie L, Schmal, Hagen, Seidenstuecker, Michael
Published in Biomedicines (25.11.2023)
Published in Biomedicines (25.11.2023)
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Journal Article
Smooth Muscle-Like Cells Generated from Human Mesenchymal Stromal Cells Display Marker Gene Expression and Electrophysiological Competence Comparable to Bladder Smooth Muscle Cells
Brun, Juliane, Lutz, Katrin A, Neumayer, Katharina M H, Klein, Gerd, Seeger, Tanja, Uynuk-Ool, Tatiana, Wörgötter, Katharina, Schmid, Sandra, Kraushaar, Udo, Guenther, Elke, Rolauffs, Bernd, Aicher, Wilhelm K, Hart, Melanie L
Published in PloS one (16.12.2015)
Published in PloS one (16.12.2015)
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Journal Article
Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition
Rothdiener, Miriam, Hegemann, Miriam, Uynuk-Ool, Tatiana, Walters, Brandan, Papugy, Piruntha, Nguyen, Phong, Claus, Valentin, Seeger, Tanja, Stoeckle, Ulrich, Boehme, Karen A., Aicher, Wilhelm K., Stegemann, Jan P., Hart, Melanie L., Kurz, Bodo, Klein, Gerd, Rolauffs, Bernd
Published in Scientific reports (24.10.2016)
Published in Scientific reports (24.10.2016)
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