Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis
Gieseck, Richard L., Ramalingam, Thirumalai R., Hart, Kevin M., Vannella, Kevin M., Cantu, David A., Lu, Wei-Yu, Ferreira-González, Sofía, Forbes, Stuart J., Vallier, Ludovic, Wynn, Thomas A.
Published in Immunity (Cambridge, Mass.) (19.07.2016)
Published in Immunity (Cambridge, Mass.) (19.07.2016)
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Journal Article
Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis
Vannella, Kevin M, Ramalingam, Thirumalai R, Borthwick, Lee A, Barron, Luke, Hart, Kevin M, Thompson, Robert W, Kindrachuk, Kristen N, Cheever, Allen W, White, Sandra, Budelsky, Alison L, Comeau, Michael R, Smith, Dirk E, Wynn, Thomas A
Published in Science translational medicine (04.05.2016)
Published in Science translational medicine (04.05.2016)
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Journal Article
Incomplete deletion of IL-4Rα by LysM(Cre) reveals distinct subsets of M2 macrophages controlling inflammation and fibrosis in chronic schistosomiasis
Vannella, Kevin M, Barron, Luke, Borthwick, Lee A, Kindrachuk, Kristen N, Narasimhan, Prakash Babu, Hart, Kevin M, Thompson, Robert W, White, Sandra, Cheever, Allen W, Ramalingam, Thirumalai R, Wynn, Thomas A
Published in PLoS pathogens (01.09.2014)
Published in PLoS pathogens (01.09.2014)
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Journal Article
Fibroblast‐specific integrin‐alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis
Sciurba, Joshua C, Gieseck, Richard L, Jiwrajka, Nikhil, White, Sandra D, Karmele, Erik P, Redes, Jamie, Vannella, Kevin M, Henderson, Neil C, Wynn, Thomas A, Hart, Kevin M
Published in The Journal of pathology (01.05.2019)
Published in The Journal of pathology (01.05.2019)
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Journal Article
Acidic chitinase primes the protective immune response to gastrointestinal nematodes
Vannella, Kevin M, Ramalingam, Thirumalai R, Hart, Kevin M, de Queiroz Prado, Rafael, Sciurba, Joshua, Barron, Luke, Borthwick, Lee A, Smith, Allen D, Mentink-Kane, Margaret, White, Sandra, Thompson, Robert W, Cheever, Allen W, Bock, Kevin, Moore, Ian, Fitz, Lori J, Urban, Joseph F, Wynn, Thomas A
Published in Nature immunology (01.05.2016)
Published in Nature immunology (01.05.2016)
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Journal Article
IL-10 immunomodulation of myeloid cells regulates a murine model of ovarian cancer
Hart, Kevin M, Byrne, Katelyn T, Molloy, Michael J, Usherwood, Edward M, Berwin, Brent
Published in Frontiers in immunology (01.01.2011)
Published in Frontiers in immunology (01.01.2011)
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Journal Article
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma
Choy, David F, Hart, Kevin M, Borthwick, Lee A, Shikotra, Aarti, Nagarkar, Deepti R, Siddiqui, Salman, Jia, Guiquan, Ohri, Chandra M, Doran, Emma, Vannella, Kevin M, Butler, Claire A, Hargadon, Beverley, Sciurba, Joshua C, Gieseck, Richard L, Thompson, Robert W, White, Sandra, Abbas, Alexander R, Jackman, Janet, Wu, Lawren C, Egen, Jackson G, Heaney, Liam G, Ramalingam, Thirumalai R, Arron, Joseph R, Wynn, Thomas A, Bradding, Peter
Published in Science translational medicine (19.08.2015)
Published in Science translational medicine (19.08.2015)
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Journal Article
Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β
Hart, Kevin M, Fabre, Thomas, Sciurba, Joshua C, Gieseck, 3rd, Richard L, Borthwick, Lee A, Vannella, Kevin M, Acciani, Thomas H, de Queiroz Prado, Rafael, Thompson, Robert W, White, Sandra, Soucy, Genevieve, Bilodeau, Marc, Ramalingam, Thirumalai R, Arron, Joseph R, Shoukry, Naglaa H, Wynn, Thomas A
Published in Science translational medicine (28.06.2017)
Published in Science translational medicine (28.06.2017)
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Journal Article
Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation
Fabre, Thomas, Barron, Alexander M S, Christensen, Stephen M, Asano, Shoh, Bound, Kathryn, Lech, Matthew P, Wadsworth, 2nd, Marc H, Chen, Xiao, Wang, Chang, Wang, Ju, McMahon, James, Schlerman, Franklin, White, Alexis, Kravarik, Kellie M, Fisher, Andrew J, Borthwick, Lee A, Hart, Kevin M, Henderson, Neil C, Wynn, Thomas A, Dower, Ken
Published in Science immunology (14.04.2023)
Published in Science immunology (14.04.2023)
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Journal Article
Enhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-γ
Ramalingam, Thirumalai R, Gieseck, Richard L, Acciani, Thomas H, M Hart, Kevin, Cheever, Allen W, Mentink-Kane, Margaret M, Vannella, Kevin M, Wynn, Thomas A
Published in The Journal of pathology (01.07.2016)
Published in The Journal of pathology (01.07.2016)
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Journal Article
Phenotypic and functional delineation of murine CX(3)CR1 monocyte-derived cells in ovarian cancer
Hart, Kevin M, Bak, S Peter, Alonso, Anselmo, Berwin, Brent
Published in Neoplasia (New York, N.Y.) (01.06.2009)
Published in Neoplasia (New York, N.Y.) (01.06.2009)
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Journal Article
Phenotypic and Functional Delineation of Murine CX3CR1+ Monocyte-Derived Cells in Ovarian Cancer
Hart, Kevin M., Bak, S. Peter, Alonso, Anselmo, Berwin, Brent
Published in Neoplasia (New York, N.Y.) (01.06.2009)
Published in Neoplasia (New York, N.Y.) (01.06.2009)
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Journal Article
Accurately measuring and modeling Th2 and Th17 endotypes in severe asthma
Hart, Kevin M, Choy, David F, Bradding, Peter, Wynn, Thomas A, Arron, Joseph R
Published in Annals of translational medicine (01.02.2017)
Published in Annals of translational medicine (01.02.2017)
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Journal Article
Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis
Borthwick, L A, Barron, L, Hart, K M, Vannella, K M, Thompson, R W, Oland, S, Cheever, A, Sciurba, J, Ramalingam, T R, Fisher, A J, Wynn, T A
Published in Mucosal immunology (01.01.2016)
Published in Mucosal immunology (01.01.2016)
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Journal Article
Enhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-γ: Dual blockade of IL-13 and IFN-γ for fibrosis
Ramalingam, Thirumalai R, Gieseck, Richard L, Acciani, Thomas H, M Hart, Kevin, Cheever, Allen W, Mentink-Kane, Margaret M, Vannella, Kevin M, Wynn, Thomas A
Published in The Journal of pathology (01.07.2016)
Published in The Journal of pathology (01.07.2016)
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Journal Article
Enhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-[gamma]
Ramalingam, Thirumalai R, Gieseck, Richard L, Acciani, Thomas H, M Hart, Kevin, Cheever, Allen W, Mentink-Kane, Margaret M, Vannella, Kevin M, Wynn, Thomas A
Published in The Journal of pathology (01.07.2016)
Published in The Journal of pathology (01.07.2016)
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Journal Article
Incomplete Deletion of IL-4Rα by LysMCre Reveals Distinct Subsets of M2 Macrophages Controlling Inflammation and Fibrosis in Chronic Schistosomiasis
Vannella, Kevin M., Barron, Luke, Borthwick, Lee A., Kindrachuk, Kristen N., Narasimhan, Prakash Babu, Hart, Kevin M., Thompson, Robert W., White, Sandra, Cheever, Allen W., Ramalingam, Thirumalai R., Wynn, Thomas A.
Published in PLoS pathogens (11.09.2014)
Published in PLoS pathogens (11.09.2014)
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Journal Article