APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity
Swanton, Charles, McGranahan, Nicholas, Starrett, Gabriel J, Harris, Reuben S
Published in Cancer discovery (01.07.2015)
Published in Cancer discovery (01.07.2015)
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Journal Article
APOBEC Enzymes as Targets for Virus and Cancer Therapy
Olson, Margaret E., Harris, Reuben S., Harki, Daniel A.
Published in Cell chemical biology (18.01.2018)
Published in Cell chemical biology (18.01.2018)
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Journal Article
The Restriction Factors of Human Immunodeficiency Virus
Harris, Reuben S., Hultquist, Judd F., Evans, David T.
Published in The Journal of biological chemistry (30.11.2012)
Published in The Journal of biological chemistry (30.11.2012)
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Journal Article
The APOBEC3 family of retroelement restriction factors
Refsland, Eric W, Harris, Reuben S
Published in Current topics in microbiology and immunology (01.01.2013)
Published in Current topics in microbiology and immunology (01.01.2013)
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Journal Article
Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses
Verhalen, Brandy, Starrett, Gabriel J, Harris, Reuben S, Jiang, Mengxi
Published in Journal of virology (15.07.2016)
Published in Journal of virology (15.07.2016)
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Journal Article
Cellular Assays for Dynamic Quantification of Deubiquitinase Activity and Inhibition
Moghadasi, Seyed Arad, Moraes, Sofia N., Harris, Reuben S.
Published in Journal of molecular biology (01.12.2023)
Published in Journal of molecular biology (01.12.2023)
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Journal Article
Studies on antiviral resistant SARS-CoV-2 Mpro mutants
Esler, Morgan A., Moghadasi, Arad, Harris, Reuben S., Aihara, Hideki
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
APOBEC3B is an enzymatic source of mutation in breast cancer
Burns, Michael B., Lackey, Lela, Carpenter, Michael A., Rathore, Anurag, Land, Allison M., Leonard, Brandon, Refsland, Eric W., Kotandeniya, Delshanee, Tretyakova, Natalia, Nikas, Jason B., Yee, Douglas, Temiz, Nuri A., Donohue, Duncan E., McDougle, Rebecca M., Brown, William L., Law, Emily K., Harris, Reuben S.
Published in Nature (London) (21.02.2013)
Published in Nature (London) (21.02.2013)
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Journal Article
APOBEC3A catalyzes mutation and drives carcinogenesis in vivo
Law, Emily K, Levin-Klein, Rena, Jarvis, Matthew C, Kim, Hyoung, Argyris, Prokopios P, Carpenter, Michael A, Starrett, Gabriel J, Temiz, Nuri A, Larson, Lindsay K, Durfee, Cameron, Burns, Michael B, Vogel, Rachel I, Stavrou, Spyridon, Aguilera, Alexya N, Wagner, Sandra, Largaespada, David A, Starr, Timothy K, Ross, Susan R, Harris, Reuben S
Published in The Journal of experimental medicine (07.12.2020)
Published in The Journal of experimental medicine (07.12.2020)
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Journal Article
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA
Bergstrom, Erik N., Luebeck, Jens, Petljak, Mia, Khandekar, Azhar, Barnes, Mark, Zhang, Tongwu, Steele, Christopher D., Pillay, Nischalan, Landi, Maria Teresa, Bafna, Vineet, Mischel, Paul S., Harris, Reuben S., Alexandrov, Ludmil B.
Published in Nature (London) (17.02.2022)
Published in Nature (London) (17.02.2022)
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Journal Article
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
Shi, Ke, Carpenter, Michael A, Banerjee, Surajit, Shaban, Nadine M, Kurahashi, Kayo, Salamango, Daniel J, McCann, Jennifer L, Starrett, Gabriel J, Duffy, Justin V, Demir, Özlem, Amaro, Rommie E, Harki, Daniel A, Harris, Reuben S, Aihara, Hideki
Published in Nature structural & molecular biology (01.02.2017)
Published in Nature structural & molecular biology (01.02.2017)
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Journal Article
Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain
Shi, Ke, Carpenter, Michael A., Kurahashi, Kayo, Harris, Reuben S., Aihara, Hideki
Published in The Journal of biological chemistry (20.11.2015)
Published in The Journal of biological chemistry (20.11.2015)
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Journal Article
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
Harris, Reuben S, Stenglein, Mark D, Burns, Michael B, Li, Ming, Lengyel, Joy
Published in Nature structural & molecular biology (01.02.2010)
Published in Nature structural & molecular biology (01.02.2010)
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Journal Article
Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1
HULTQUIST, Judd F, LENGYEL, Joy A, REFSLAND, Eric W, LARUE, Rebecca S, LACKEY, Lela, BROWN, William L, HARRIS, Reuben S
Published in Journal of Virology (01.11.2011)
Published in Journal of Virology (01.11.2011)
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Journal Article
Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
Carpenter, Michael A, Temiz, Nuri A, Ibrahim, Mahmoud A, Jarvis, Matthew C, Brown, Margaret R, Argyris, Prokopios P, Brown, William L, Starrett, Gabriel J, Yee, Douglas, Harris, Reuben S
Published in PLoS genetics (30.11.2023)
Published in PLoS genetics (30.11.2023)
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Journal Article
A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans
Nakano, Yusuke, Yamamoto, Keisuke, Ueda, Mahoko Takahashi, Soper, Andrew, Konno, Yoriyuki, Kimura, Izumi, Uriu, Keiya, Kumata, Ryuichi, Aso, Hirofumi, Misawa, Naoko, Nagaoka, Shumpei, Shimizu, Soma, Mitsumune, Keito, Kosugi, Yusuke, Juarez-Fernandez, Guillermo, Ito, Jumpei, Nakagawa, So, Ikeda, Terumasa, Koyanagi, Yoshio, Harris, Reuben S, Sato, Kei, Cullen, Bryan R, Hope, Thomas J
Published in PLoS pathogens (10.09.2020)
Published in PLoS pathogens (10.09.2020)
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