B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis
Parker Harp, Chelsea R, Archambault, Angela S, Sim, Julia, Shlomchik, Mark J, Russell, John H, Wu, Gregory F
Published in PloS one (26.06.2018)
Published in PloS one (26.06.2018)
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Neutrophils promote VLA-4–dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation
Harp, Chelsea R. Parker, Archambault, Angela S., Cheung, Matthew, Williams, Jesse W., Czepielewski, Rafael S., Duncker, Patrick C., Kilgore, Aaron J., Miller, Aidan T., Segal, Benjamin M., Kim, Alfred H. J., Randolph, Gwendalyn J., Wu, Gregory F.
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2019)
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B cell antigen presentation is sufficient to drive neuroinflammation in an animal model of multiple sclerosis
Parker Harp, Chelsea R, Archambault, Angela S, Sim, Julia, Ferris, Stephen T, Mikesell, Robert J, Koni, Pandelakis A, Shimoda, Michiko, Linington, Christopher, Russell, John H, Wu, Gregory F
Published in The Journal of immunology (1950) (01.06.2015)
Published in The Journal of immunology (1950) (01.06.2015)
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Preclinical Analysis of Candidate Anti-Human CD79 Therapeutic Antibodies Using a Humanized CD79 Mouse Model
Wemlinger, Scott M, Parker Harp, Chelsea R, Yu, Bo, Hardy, Ian R, Seefeldt, Matthew, Matsuda, Jennifer, Mingueneau, Michael, Spilker, Kerri A, Cameron, Thomas O, Larrick, James W, Getahun, Andrew, Cambier, John C
Published in The Journal of immunology (1950) (01.04.2022)
Published in The Journal of immunology (1950) (01.04.2022)
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Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis
Himmelbauer, Martin K., Bajrami, Bekim, Basile, Rebecca, Capacci, Andrew, Chen, TeYu, Choi, Colin K., Gilfillan, Rab, Gonzalez-Lopez de Turiso, Felix, Gu, Chungang, Hoemberger, Marc, Johnson, Douglas S., Jones, J. Howard, Kadakia, Ekta, Kirkland, Melissa, Lin, Edward Y., Liu, Ying, Ma, Bin, Magee, Tom, Mantena, Srinivasa, Marx, Isaac E., Metrick, Claire M., Mingueneau, Michael, Murugan, Paramasivam, Muste, Cathy A., Nadella, Prasad, Nevalainen, Marta, Parker Harp, Chelsea R., Pattaropong, Vatee, Pietrasiewicz, Alicia, Prince, Robin J., Purgett, Thomas J., Santoro, Joseph C., Schulz, Jurgen, Sciabola, Simone, Tang, Hao, Vandeveer, H. George, Wang, Ti, Yousaf, Zain, Helal, Christopher J., Hopkins, Brian T.
Published in Journal of medicinal chemistry (23.05.2024)
Published in Journal of medicinal chemistry (23.05.2024)
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MOG autoantibodies trigger a tightly-controlled FcR and BTK-driven microglia proliferative response
Pellerin, Kathryn, Rubino, Stephen J, Burns, Jeremy C, Smith, Benjamin A, McCarl, Christie-Ann, Zhu, Jing, Jandreski, Luke, Cullen, Patrick, Carlile, Thomas M, Li, Angela, Rebollar, Jorge Vera, Sybulski, Jennifer, Reynolds, Taylor L, Zhang, Baohong, Basile, Rebecca, Tang, Hao, Harp, Chelsea Parker, Pellerin, Alex, Silbereis, John, Franchimont, Nathalie, Cahir-McFarland, Ellen, Ransohoff, Richard M, Cameron, Thomas O, Mingueneau, Michael
Published in Brain (London, England : 1878) (04.09.2021)
Published in Brain (London, England : 1878) (04.09.2021)
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Journal Article
VLA4 expression by B cells enables B cell-restricted antigen presentation to support CD4 T cell driven central nervous system autoimmunity
Parker Harp, Chelsea R., Archambault, Angela S., Sim, Julia, Carrero, Javier A., Russell, John, Wu, Gregory F.
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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Journal Article
B cell antigen presentation is sufficient to drive neuro-inflammation in an animal model of multiple sclerosis1
Parker Harp, Chelsea R., Archambault, Angela S., Sim, Julia, Ferris, Stephen T., Mikesell, Robert J., Koni, Pandelakis A., Shimoda, Michiko, Linington, Christopher, Russell, John H., Wu, Gregory F.
Published in The Journal of immunology (1950) (20.04.2015)
Published in The Journal of immunology (1950) (20.04.2015)
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Journal Article
COMBINATION TREATMENT METHODS OF MULTIPLE SCLEROSIS
Hopkins, Brian T, Pellerin, Alex, Scaramozza, Matthew P, Barbey, Catherine, Mingueneau, Michael Christian, Palte, Michael Joseph, Parker Harp, Chelsea R
Year of Publication 04.07.2024
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Year of Publication 04.07.2024
Patent
COMBINATION TREATMENT METHODS OF MULTIPLE SCLEROSIS
SCARAMOZZA, Mathew, MINGUENAU, Michael, BARBEY, Catherine, PELLERIN, Alex, PARKER HARP, Chelsea, HOPKINS, Brian, PALTE, Michael
Year of Publication 06.10.2022
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Year of Publication 06.10.2022
Patent