Foot-and-mouth disease virus antigenic landscape and reduced immunogenicity elucidated in atomic detail
Li, Haozhou, Liu, Pan, Dong, Hu, Dekker, Aldo, Harmsen, Michiel M., Guo, Huichen, Wang, Xiangxi, Sun, Shiqi
Published in Nature communications (10.10.2024)
Published in Nature communications (10.10.2024)
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Journal Article
Identification of the Structural Basis of Thermal Lability of a Virus Provides a Rationale for Improved Vaccines
Rincón, Verónica, Rodríguez-Huete, Alicia, López-Argüello, Silvia, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M., Harmsen, Michiel M., Mateu, Mauricio G.
Published in Structure (London) (04.11.2014)
Published in Structure (London) (04.11.2014)
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Journal Article
Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies
Dong, Hu, Liu, Pan, Bai, Manyuan, Wang, Kang, Feng, Rui, Zhu, Dandan, Sun, Yao, Mu, Suyu, Li, Haozhou, Harmsen, Michiel, Sun, Shiqi, Wang, Xiangxi, Guo, Huichen
Published in Protein & cell (01.06.2022)
Published in Protein & cell (01.06.2022)
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Journal Article
A novel single-domain antibody multimer that potently neutralizes tetanus neurotoxin
de Smit, Hans, Ackerschott, Bart, Tierney, Robert, Stickings, Paul, Harmsen, Michiel M.
Published in Vaccine: X (01.08.2021)
Published in Vaccine: X (01.08.2021)
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Journal Article
Isolation of Single-Domain Antibody Fragments That Preferentially Detect Intact (146S) Particles of Foot-and-Mouth Disease Virus for Use in Vaccine Quality Control
Harmsen, Michiel M, Seago, Julian, Perez, Eva, Charleston, Bryan, Eblé, Phaedra L, Dekker, Aldo
Published in Frontiers in immunology (17.08.2017)
Published in Frontiers in immunology (17.08.2017)
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Journal Article
The effect of uniform capture molecule orientation on biosensor sensitivity: Dependence on analyte properties
Trilling, Anke K., Harmsen, Michiel M., Ruigrok, Vincent J.B., Zuilhof, Han, Beekwilder, Jules
Published in Biosensors & bioelectronics (15.02.2013)
Published in Biosensors & bioelectronics (15.02.2013)
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Journal Article
Conference Proceeding
Mapping of foot-and-mouth disease virus antigenic sites recognized by single-domain antibodies reveals different 146S particle specific sites and particle flexibility
Harmsen, Michiel M, Li, Haozhou, Sun, Shiqi, van der Poel, Wim H M, Dekker, Aldo
Published in Frontiers in veterinary science (09.01.2023)
Published in Frontiers in veterinary science (09.01.2023)
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Journal Article
Chimeric O1K foot-and-mouth disease virus with SAT2 outer capsid as an FMD vaccine candidate
Kotecha, Abhay, Perez-Martin, Eva, Harvey, Yongjie, Zhang, Fuquan, Ilca, Serban L, Fry, Elizabeth E., Jackson, Ben, Maree, Francois, Scott, Katherine, Hecksel, Corey W., Harmsen, Michiel M., Mioulet, Valérie, Wood, Britta, Juleff, Nick, Stuart, David I., Charleston, Bryan, Seago, Julian
Published in Scientific reports (12.09.2018)
Published in Scientific reports (12.09.2018)
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Journal Article
Novel Capsid-Specific Single-Domain Antibodies with Broad Foot-and-Mouth Disease Strain Recognition Reveal Differences in Antigenicity of Virions, Empty Capsids, and Virus-Like Particles
Li, Haozhou, Dekker, Aldo, Sun, Shiqi, Burman, Alison, Kortekaas, Jeroen, Harmsen, Michiel M.
Published in Vaccines (Basel) (08.06.2021)
Published in Vaccines (Basel) (08.06.2021)
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Journal Article
Multimeric single-domain antibody complexes protect against bunyavirus infections
Wichgers Schreur, Paul J, van de Water, Sandra, Harmsen, Michiel, Bermúdez-Méndez, Erick, Drabek, Dubravka, Grosveld, Frank, Wernike, Kerstin, Beer, Martin, Aebischer, Andrea, Daramola, Olalekan, Rodriguez Conde, Sara, Brennan, Karen, Kozub, Dorota, Søndergaard Kristiansen, Maiken, Mistry, Kieran K, Deng, Ziyan, Hellert, Jan, Guardado-Calvo, Pablo, Rey, Félix A, van Keulen, Lucien, Kortekaas, Jeroen
Published in eLife (21.04.2020)
Published in eLife (21.04.2020)
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Journal Article
Characterization of epitope-tagged foot-and-mouth disease virus
SEAGO, Julian, JACKSON, Terry, DOEL, Claudia, FRY, Elizabeth, STUART, David, HARMSEN, Michiel M, CHARLESTON, Bryan, JULEFF, Nicholas
Published in Journal of general virology (01.11.2012)
Published in Journal of general virology (01.11.2012)
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Journal Article
Isolation of Panels of Llama Single-Domain Antibody Fragments Binding All Nine Neuraminidase Subtypes of Influenza A Virus
Harmsen, Michiel, Blokker, Juliette, Pritz-Verschuren, Sylvia, Bartelink, Willem, Van der Burg, Herman, Koch, Guus
Published in Antibodies (Basel) (01.06.2013)
Published in Antibodies (Basel) (01.06.2013)
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Journal Article
Early immunodiagnosis of fasciolosis in ruminants using recombinant Fasciola hepatica cathepsin L-like protease
Cornelissen, Jan B.W.J, Gaasenbeek, Cor P.H, Borgsteede, Fred H.M, Holland, Wicher G, Harmsen, Michiel M, Boersma, Wim J.A
Published in International journal for parasitology (15.05.2001)
Published in International journal for parasitology (15.05.2001)
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Journal Article
Identification of a novel Fasciola hepatica cathepsin L protease containing protective epitopes within the propeptide
Harmsen, Michiel M., Cornelissen, Jan B.W.J., Buijs, Herma E.C.M., Boersma, Wim J.A., Jeurissen, Suzan H.M., van Milligen, Florine J.
Published in International journal for parasitology (01.05.2004)
Published in International journal for parasitology (01.05.2004)
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