importance of spatial models for estimating the strength of density dependence
Thorson, James T, Hans J. Skaug, Kasper Kristensen, Andrew O. Shelton, Eric J. Ward, John H. Harms, James A. Benante
Published in Ecology (Durham) (01.05.2015)
Published in Ecology (Durham) (01.05.2015)
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Facilitation of corticostriatal transmission following pharmacological inhibition of striatal phosphodiesterase 10A: role of nitric oxide-soluble guanylyl cyclase-cGMP signaling pathways
Padovan-Neto, Fernando E, Sammut, Stephen, Chakroborty, Shreaya, Dec, Alexander M, Threlfell, Sarah, Campbell, Peter W, Mudrakola, Vishnu, Harms, John F, Schmidt, Christopher J, West, Anthony R
Published in The Journal of neuroscience (08.04.2015)
Published in The Journal of neuroscience (08.04.2015)
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Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington’s Disease Models
Beaumont, Vahri, Zhong, Sheng, Lin, Hai, Xu, WenJin, Bradaia, Amyaouch, Steidl, Esther, Gleyzes, Melanie, Wadel, Kristian, Buisson, Bruno, Padovan-Neto, Fernando E., Chakroborty, Shreaya, Ward, Karen M., Harms, John F., Beltran, Jose, Kwan, Mei, Ghavami, Afshin, Häggkvist, Jenny, Tóth, Miklós, Halldin, Christer, Varrone, Andrea, Schaab, Christoph, Dybowski, J. Nikolaj, Elschenbroich, Sarah, Lehtimäki, Kimmo, Heikkinen, Taneli, Park, Larry, Rosinski, James, Mrzljak, Ladislav, Lavery, Daniel, West, Anthony R., Schmidt, Christopher J., Zaleska, Margaret M., Munoz-Sanjuan, Ignacio
Published in Neuron (Cambridge, Mass.) (21.12.2016)
Published in Neuron (Cambridge, Mass.) (21.12.2016)
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Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia
Verhoest, Patrick R., Chapin, Douglas S., Corman, Michael, Fonseca, Kari, Harms, John F., Hou, Xinjun, Marr, Eric S., Menniti, Frank S., Nelson, Frederick, O'Connor, Rebecca, Pandit, Jayvardhan, Proulx-LaFrance, Caroline, Schmidt, Anne W., Schmidt, Christopher J., Suiciak, Judith A., Liras, Spiros
Published in Journal of medicinal chemistry (27.08.2009)
Published in Journal of medicinal chemistry (27.08.2009)
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Inhibition of the striatum-enriched phosphodiesterase PDE10A: A novel approach to the treatment of psychosis
Siuciak, Judith A., Chapin, Douglas S., Harms, John F., Lebel, Lorraine A., McCarthy, Sheryl A., Chambers, Leslie, Shrikhande, Alka, Wong, Stephen, Menniti, Frank S., Schmidt, Christopher J.
Published in Neuropharmacology (01.08.2006)
Published in Neuropharmacology (01.08.2006)
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Chronic suppression of phosphodiesterase 10A alters striatal expression of genes responsible for neurotransmitter synthesis, neurotransmission, and signaling pathways implicated in Huntington's disease
Kleiman, Robin J, Kimmel, Lida H, Bove, Susan E, Lanz, Thomas A, Harms, John F, Romegialli, Alison, Miller, Kenneth S, Willis, Amy, des Etages, Shelley, Kuhn, Max, Schmidt, Christopher J
Published in The Journal of pharmacology and experimental therapeutics (01.01.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2011)
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Sandwiching analytes with structurally diverse plasmonic nanoparticles on paper substrates for surface enhanced Raman spectroscopy
Lartey, Jemima A, Harms, John P, Frimpong, Richard, Mulligan, Christopher C, Driskell, Jeremy D, Kim, Jun-Hyun
Published in RSC advances (11.10.2019)
Published in RSC advances (11.10.2019)
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Investigating three sources of bias in hook-and-line surveys: survey design, gear saturation, and multispecies interactions
Kuriyama, Peter T, Branch, Trevor A, Hicks, Allan C, Harms, John H, Hamel, Owen S
Published in Canadian journal of fisheries and aquatic sciences (01.02.2019)
Published in Canadian journal of fisheries and aquatic sciences (01.02.2019)
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Journal Article
CCK Receptor Inhibition Reduces Pancreatic Tumor Fibrosis and Promotes Nanoparticle Delivery
Abraham, Thomas, Armold, Michael, McGovern, Christopher, Harms, John F, Darok, Matthew C, Gigliotti, Christopher, Adair, Bernadette, Gray, Jennifer L, Kelly, Deborah F, Adair, James H, Matters, Gail L
Published in Biomedicines (01.05.2024)
Published in Biomedicines (01.05.2024)
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Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate
Helal, Christopher J, Arnold, Eric, Boyden, Tracey, Chang, Cheng, Chappie, Thomas A, Fisher, Ethan, Hajos, Mihaly, Harms, John F, Hoffman, William E, Humphrey, John M, Pandit, Jayvardhan, Kang, Zhijun, Kleiman, Robin J, Kormos, Bethany L, Lee, Che-Wah, Lu, Jiemin, Maklad, Noha, McDowell, Laura, McGinnis, Dina, O’Connor, Rebecca E, O’Donnell, Christopher J, Ogden, Adam, Piotrowski, Mary, Schmidt, Christopher J, Seymour, Patricia A, Ueno, Hirokazu, Vansell, Nichole, Verhoest, Patrick R, Yang, Edward X
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Striatal, Hippocampal, and Cortical Networks Are Differentially Responsive to the M4- and M1-Muscarinic Acetylcholine Receptor Mediated Effects of Xanomeline
Thorn, Catherine A, Moon, Joshua, Bourbonais, Clinton A, Harms, John, Edgerton, Jeremy R, Stark, Eda, Steyn, Stefanus J, Butter, Christopher R, Lazzaro, John T, O’Connor, Rebecca E, Popiolek, Michael
Published in ACS chemical neuroscience (20.03.2019)
Published in ACS chemical neuroscience (20.03.2019)
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Phosphodiesterase 9A in Brain Regulates cGMP Signaling Independent of Nitric-Oxide
Harms, John F, Menniti, Frank S, Schmidt, Christopher J
Published in Frontiers in neuroscience (23.08.2019)
Published in Frontiers in neuroscience (23.08.2019)
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A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris
Cerini, Fabrice, Gaertner, Hubert, Madden, Knut, Tolstorukov, Ilya, Brown, Scott, Laukens, Bram, Callewaert, Nico, Harner, Jay C., Oommen, Anna M., Harms, John T., Sump, Anthony R., Sealock, Robert C., Peterson, Dustin J., Johnson, Scott K., Abramson, Stephan B., Meagher, Michael, Offord, Robin, Hartley, Oliver
Published in Protein expression and purification (01.03.2016)
Published in Protein expression and purification (01.03.2016)
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Tu1923 A Single Nucleotide Polymorphism of the CCK-B Receptor Does Not Effect Survival in Colon & Gastric Cancer
Alsubai, Jelal, Smith, Jill P, McGovern, Christopher, Matters, Gail, Harms, John F, Liao, Jiangang
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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A single nucleotide polymorphism of the cholecystokinin-B receptor predicts risk for pancreatic cancer
Smith, Jill P., Harms, John, Matters, Gail L., McGovern, Christopher O., Ruggiero, Francesca M., Liao, Jiangang, Fino, Kristin K., Ortega, Emily E., Gilius, Evan L., Phillips III, John A.
Published in Cancer biology & therapy (01.02.2012)
Published in Cancer biology & therapy (01.02.2012)
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Journal Article
Kinetics of Metastatic Breast Cancer Cell Trafficking in Bone
PHADKE, Pushkar A, MERCER, Robyn R, GAY, Carol V, MASTRO, Andrea M, WELCH, Danny R, HARMS, John F, YUJIANG JIA, FROST, Andra R, JEWELL, Jennifer L, BUSSARD, Karen M, NELSON, Shakira, MOORE, Cynthia, KAPPES, John C
Published in Clinical cancer research (01.03.2006)
Published in Clinical cancer research (01.03.2006)
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Journal Article
Correction to Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor
Helal, Christopher J, Arnold, Eric P, Boyden, Tracey L, Chang, Cheng, Chappie, Thomas A, Fennell, Kimberly F, Forman, Michael D, Hajos, Mihaly, Harms, John F, Hoffman, William E, Humphrey, John M, Kang, Zhijun, Kleiman, Robin J, Kormos, Bethany L, LaChapelle, Erik A, Lee, Che-Wah, Lu, Jiemin, Maklad, Noha, McDowell, Laura, Mente, Scot, O’Connor, Rebecca E, Pandit, Jayvardhan, Piotrowski, Mary, Schmidt, Anne W, Schmidt, Christopher J, Ueno, Hirokazu, Verhoest, Patrick R, Yang, Edward X
Published in Journal of medicinal chemistry (26.04.2018)
Published in Journal of medicinal chemistry (26.04.2018)
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Vagotomy enhances experimental metastases of 4THMpc breast cancer cells and alters Substance P level
Erin, Nuray, Akdas Barkan, Güliz, Harms, John F., Clawson, Gary A.
Published in Regulatory peptides (29.11.2008)
Published in Regulatory peptides (29.11.2008)
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