Sequence analyses and comparative modeling of fly and worm fibroblast growth factor receptors indicate that the determinants for FGF and heparin binding are retained in evolution
Nagendra, H.G, Harrington, Adrian E, Harmer, Nicholas J, Pellegrini, Luca, Blundell, Tom L, Burke, David F
Published in FEBS letters (13.07.2001)
Published in FEBS letters (13.07.2001)
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Journal Article
Predicting Protein Function from Structure—The Roles of Short-chain Dehydrogenase/Reductase Enzymes in Bordetella O-antigen Biosynthesis
King, Jerry D., Harmer, Nicholas J., Preston, Andrew, Palmer, Colin M., Rejzek, Martin, Field, Robert A., Blundell, Tom L., Maskell, Duncan J.
Published in Journal of molecular biology (30.11.2007)
Published in Journal of molecular biology (30.11.2007)
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Journal Article
Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery
Blundell, Tom L, Sibanda, Bancinyane L, Montalvão, Rinaldo Wander, Brewerton, Suzanne, Chelliah, Vijayalakshmi, Worth, Catherine L, Harmer, Nicholas J, Davies, Owen, Burke, David
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29.03.2006)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29.03.2006)
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The Crystal Structure of Fibroblast Growth Factor (FGF) 19 Reveals Novel Features of the FGF Family and Offers a Structural Basis for Its Unusual Receptor Affinity
Harmer, Nicholas J, Pellegrini, Luca, Chirgadze, Dima, Fernandez-Recio, Juan, Blundell, Tom L
Published in Biochemistry (Easton) (27.01.2004)
Published in Biochemistry (Easton) (27.01.2004)
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Journal Article
Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin
Harmer, Nicholas J, Robinson, Christopher J, Adam, Lucy E, Ilag, Leopold L, Robinson, Carol V, Gallagher, John T, Blundell, Tom L
Published in Biochemical journal (01.02.2006)
Published in Biochemical journal (01.02.2006)
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Journal Article
A tyrosine703serine polymorphism of CD109 defines the Gov platelet alloantigens
Schuh, Andre C., Watkins, Nick A., Nguyen, Quang, Harmer, Nicholas J., Lin, Martin, Prosper, Joseph Y.A., Campbell, Kate, Sutherland, D. Robert, Metcalfe, Paul, Horsfall, Wendy, Ouwehand, Willem H.
Published in Blood (01.03.2002)
Published in Blood (01.03.2002)
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Journal Article
The structural biology of growth factor receptor activation
Harmer, Nicholas J., Chirgadze, Dima, Hyun Kim, Kyung, Pellegrini, Luca, Blundell, Tom L.
Published in Biophysical chemistry (01.01.2003)
Published in Biophysical chemistry (01.01.2003)
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