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Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability
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Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors
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Identification and Validation of an Anthracycline/ Cyclophosphamide-Based Chemotherapy Response Assay in Breast Cancer
MULLIGAN, Jude M, HILL, Laura A, QUINN, Jennifer E, LINDOR, Noralane M, MULLAN, Paul B, JAMES, Colin R, WALKER, Steven M, KERR, Peter, JAMES, Jacqueline, DAVISON, Timothy S, PROUTSKI, Vitali, SALTO-TELLEZ, Manuel, DEHARO, Steve, JOHNSTON, Patrick G, COUCH, Fergus J, HARKIN, D. Paul, KENNEDY, Richard D, IRWIN, Gareth, BOYLE, David, KEATING, Katherine E, RAJI, Olaide Y, MCDYER, Fionnuala A, O'BRIEN, Eamonn, BYLESJO, Max
Published in JNCI : Journal of the National Cancer Institute (01.01.2014)
Published in JNCI : Journal of the National Cancer Institute (01.01.2014)
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The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export
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Published in Nucleic acids research (15.12.2017)
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The Role of BRCA1 in the Cellular Response to Chemotherapy
Kennedy, Richard D., Quinn, Jennifer E., Mullan, Paul B., Johnston, Patrick G., Harkin, D. Paul
Published in JNCI : Journal of the National Cancer Institute (17.11.2004)
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Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer
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Published in Laboratory investigation (01.01.2018)
Published in Laboratory investigation (01.01.2018)
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RNA expression analysis from formalin fixed paraffin embedded tissues
Farragher, Susan M., Tanney, Austin, Kennedy, Richard D., Paul Harkin, D.
Published in Histochemistry and cell biology (01.09.2008)
Published in Histochemistry and cell biology (01.09.2008)
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Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer
Parkes, Eileen E., Savage, Kienan I., Lioe, Tong, Boyd, Clinton, Halliday, Sophia, Walker, Steven M., Lowry, Keith, Knight, Laura, Buckley, Niamh E., Grogan, Andrena, Logan, Gemma E., Clayton, Alison, Hurwitz, Jane, Kirk, Stephen J., Xu, Jiamei, Sidi, Fatima Abdullahi, Humphries, Matthew P., Bingham, Victoria, James, Jaqueline A., James, Colin R., Paul Harkin, D., Kennedy, Richard D., McIntosh, Stuart A.
Published in British journal of cancer (01.02.2022)
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Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer
McGivern, Niamh, El-Helali, Aya, Mullan, Paul, McNeish, Iain A, Paul Harkin, D, Kennedy, Richard D, McCabe, Nuala
Published in Oncotarget (12.01.2018)
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BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability
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Published in Cancer research (Chicago, Ill.) (15.05.2014)
Published in Cancer research (Chicago, Ill.) (15.05.2014)
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Development and Independent Validation of a Prognostic Assay for Stage II Colon Cancer Using Formalin-Fixed Paraffin-Embedded Tissue
KENNEDY, Richard D, BYLESJO, Max, GOFFARD, Nicolas, HEY, Peter, MCDYER, Fionnuala, MULLIGAN, Karl, MUSSEN, Julie, O'BRIEN, Eamonn, OLIVER, Gavin, WALKER, Steven M, MULLIGAN, Jude M, WILSON, Claire, KERR, Peter, WINTER, Andreas, O'DONOGHUE, Diarmuid, MULCAHY, Hugh, O'SULLIVAN, Jacintha, SHEAHAN, Kieran, HYLAND, John, DHIR, Rajiv, BATHE, Oliver F, WINQVIST, Ola, MANNE, Upender, DAVISON, Timothy, SHANMUGAM, Chandrakumar, RAMASWAMY, Sridhar, LEON, Eduardo J, SMITH, William I, MCDERMOTT, Ultan, WILSON, Richard H, LONGLEY, Daniel, MARSHALL, John, CUMMINS, Robert, SARGENT, Daniel J, BLACK, Julie M, JOHNSTON, Patrick G, PAUL HARKIN, D, KAY, Elaine W, HOLT, Robert J, PROUTSKI, Vitali, AHDESMAKI, Miika, FARZTDINOV, Vadim
Published in Journal of clinical oncology (10.12.2011)
Published in Journal of clinical oncology (10.12.2011)
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High EMSY expression defines a BRCA‐like subgroup of high‐grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum
Hollis, Robert L., Churchman, Michael, Michie, Caroline O., Rye, Tzyvia, Knight, Laura, McCavigan, Andrena, Perren, Timothy, Williams, Alistair R. W., McCluggage, W. Glenn, Kaplan, Richard S., Jayson, Gordon C., Oza, Amit, Harkin, D. Paul, Herrington, C. Simon, Kennedy, Richard, Gourley, Charlie
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Published in Cancer (15.08.2019)
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Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
Hollis, Robert L, Meynert, Alison M, Michie, Caroline O, Rye, Tzyvia, Churchman, Michael, Hallas-Potts, Amelia, Croy, Ian, McCluggage, W Glenn, Williams, Alistair R W, Bartos, Clare, Iida, Yasushi, Okamoto, Aikou, Dougherty, Brian, Barrett, J Carl, March, Ruth, Matakidou, Athena, Roxburgh, Patricia, Semple, Colin A, Harkin, D Paul, Kennedy, Richard, Herrington, C Simon, Gourley, Charlie
Published in Clinical cancer research (15.08.2022)
Published in Clinical cancer research (15.08.2022)
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Mechanistic Rationale to Target PTEN-Deficient Tumor Cells with Inhibitors of the DNA Damage Response Kinase ATM
McCabe, Nuala, Hanna, Conor, Walker, Steven M, Gonda, David, Li, Jie, Wikstrom, Katarina, Savage, Kienan I, Butterworth, Karl T, Chen, Clark, Harkin, D Paul, Prise, Kevin M, Kennedy, Richard D
Published in Cancer research (Chicago, Ill.) (01.06.2015)
Published in Cancer research (Chicago, Ill.) (01.06.2015)
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Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy
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Published in Annals of oncology (01.01.2018)
Published in Annals of oncology (01.01.2018)
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