Fcγ receptors: genetic variation, function, and disease
Hargreaves, Chantal E., Rose-Zerilli, Matthew J. J., Machado, Lee R., Iriyama, Chisako, Hollox, Edward J., Cragg, Mark S., Strefford, Jonathan C.
Published in Immunological reviews (01.11.2015)
Published in Immunological reviews (01.11.2015)
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Role of obinutuzumab exposure on clinical outcome of follicular lymphoma treated with first‐line immunochemotherapy
Jamois, Candice, Gibiansky, Ekaterina, Gibiansky, Leonid, Buchheit, Vincent, Sahin, Denis, Cartron, Guillaume, Marcus, Robert, Hiddemann, Wolfgang, Seymour, John F., Strefford, Jonathan C., Hargreaves, Chantal E., Meneses‐Lorente, Georgina, Frey, Nicolas, Fingerle‐Rowson, Günter
Published in British journal of clinical pharmacology (01.07.2019)
Published in British journal of clinical pharmacology (01.07.2019)
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Journal Article
Resolving the polygenic aetiology of a late onset combined immune deficiency caused by NFKB1 haploinsufficiency and modified by PIK3R1 and TNFRSF13B variants
Hargreaves, Chantal E., Dhalla, Fatima, Patel, Arzoo M., de Oteyza, Andrés Caballero Garcia, Bateman, Elizabeth, Miller, Joanne, Anzilotti, Consuelo, Ayers, Lisa, Grimbacher, Bodo, Patel, Smita Y.
Published in Clinical immunology (Orlando, Fla.) (01.01.2022)
Published in Clinical immunology (Orlando, Fla.) (01.01.2022)
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Skewed X Chromosome Inactivation and Female Preponderance in Autoimmune Thyroid Disease: An Association Study and Meta-Analysis
Simmonds, Matthew J, Kavvoura, Fotini K, Brand, Oliver J, Newby, Paul R, Jackson, Laura E, Hargreaves, Chantal E, Franklyn, Jayne A, Gough, Stephen C. L
Published in The journal of clinical endocrinology and metabolism (01.01.2014)
Published in The journal of clinical endocrinology and metabolism (01.01.2014)
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Journal Article
HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy
Hussain, Khiyam, Liu, Rena, Smith, Rosanna C G, Müller, Kri T J, Ghorbani, Mohammadmersad, Macari, Sofia, Cleary, Kirstie L S, Oldham, Robert J, Foxall, Russell B, James, Sonya, Booth, Steven G, Murray, Tom, Dahal, Lekh N, Hargreaves, Chantal E, Kemp, Robert S, Longley, Jemma, Douglas, James, Markham, Hannah, Chee, Serena J, Stopforth, Richard J, Roghanian, Ali, Carter, Matthew J, Ottensmeier, Christian H, Frendéus, Bjorn, Cutress, Ramsey I, French, Ruth R, Glennie, Martin J, Strefford, Jonathan C, Thirdborough, Stephen M, Beers, Stephen A, Cragg, Mark S
Published in Journal of experimental & clinical cancer research (07.04.2022)
Published in Journal of experimental & clinical cancer research (07.04.2022)
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Journal Article
A Novel, Heterozygous Three Base-Pair Deletion in CARD11 Results in B Cell Expansion with NF-κB and T Cell Anergy Disease
Shields, Adrian M., Bauman, Bradly M., Hargreaves, Chantal E., Pollard, Andrew J., Snow, Andrew L., Patel, Smita Y.
Published in Journal of clinical immunology (01.02.2020)
Published in Journal of clinical immunology (01.02.2020)
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Journal Article
Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus
Hargreaves, Chantal E, Iriyama, Chisako, Rose-Zerilli, Matthew J J, Nagelkerke, Sietse Q, Hussain, Khiyam, Ganderton, Rosalind, Lee, Charlotte, Machado, Lee R, Hollox, Edward J, Parker, Helen, Latham, Kate V, Kuijpers, Taco W, Potter, Kathleen N, Coupland, Sarah E, Davies, Andrew, Stackpole, Michael, Oates, Melanie, Pettitt, Andrew R, Glennie, Martin J, Cragg, Mark S, Strefford, Jonathan C
Published in PloS one (06.11.2015)
Published in PloS one (06.11.2015)
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Journal Article
Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders
Hargreaves, Chantal E., Salatino, Silvia, Sasson, Sarah C., Charlesworth, James E. G., Bateman, Elizabeth, Patel, Arzoo M., Anzilotti, Consuelo, Broxholme, John, Knight, Julian C., Patel, Smita Y.
Published in Journal of clinical immunology (01.08.2021)
Published in Journal of clinical immunology (01.08.2021)
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Journal Article
Yersinia enterocolitica provides the link between thyroid-stimulating antibodies and their germline counterparts in Graves' disease
Hargreaves, Chantal E, Grasso, Marco, Hampe, Christiane S, Stenkova, Anna, Atkinson, Steve, Joshua, George W P, Wren, Brendan W, Buckle, Ashley M, Dunn-Walters, Deborah, Banga, J Paul
Published in The Journal of immunology (1950) (01.06.2013)
Published in The Journal of immunology (1950) (01.06.2013)
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Journal Article
Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412
Hussain, Khiyam, Hargreaves, Chantal E., Roghanian, Ali, Oldham, Robert J., Chan, H. T. Claude, Mockridge, C. Ian, Chowdhury, Ferdousi, Frendéus, Bjorn, Harper, Kirsty S., Strefford, Jonathan C., Cragg, Mark S., Glennie, Martin J., Williams, Anthony P., French, Ruth R.
Published in Blood (01.01.2015)
Published in Blood (01.01.2015)
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Journal Article
Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format
Hussain, Khiyam, Hargreaves, Chantal E, Rowley, Tania F, Sopp, Joshua M, Latham, Kate V, Bhatta, Pallavi, Sherington, John, Cutler, Rona M, Humphreys, David P, Glennie, Martin J, Strefford, Jonathan C, Cragg, Mark S
Published in Frontiers in immunology (07.03.2019)
Published in Frontiers in immunology (07.03.2019)
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Journal Article
Correction: Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus
Hargreaves, Chantal E, Iriyama, Chisako, Rose-Zerilli, Matthew J J, Nagelkerke, Sietse Q, Hussain, Khiyam, Ganderton, Rosalind, Lee, Charlotte, Machado, Lee R, Hollox, Edward J, Parker, Helen, Latham, Kate V, Kuijpers, Taco W, Potter, Kathleen N, Coupland, Sarah E, Davies, Andrew, Stackpole, Michael, Oates, Melanie, Pettitt, Andrew R, Glennie, Martin J, Cragg, Mark S, Strefford, Jonathan C
Published in PloS one (23.03.2016)
Published in PloS one (23.03.2016)
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Journal Article
Single-nucleotide Fcγ receptor polymorphisms do not impact obinutuzumab/rituximab outcome in patients with lymphoma
Strefford, Jonathan C., Nowicka, Malgorzata, Hargreaves, Chantal E., Burton, Cathy, Davies, Andrew, Ganderton, Rosalind, Hiddemann, Wolfgang, Iriyama, Chisako, Klapper, Wolfram, Latham, Kate V., Martelli, Maurizio, Mir, Farheen, Parker, Helen, Potter, Kathleen N., Rose-Zerilli, Matthew J.J., Sehn, Laurie H., Trněný, Marek, Vitolo, Umberto, Bolen, Christopher R., Klein, Christian, Knapp, Andrea, Oestergaard, Mikkel Z., Cragg, Mark S.
Published in Blood advances (10.08.2021)
Published in Blood advances (10.08.2021)
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Journal Article
Prognostic significance of FCGR2B expression for the response of DLBCL patients to rituximab or obinutuzumab treatment
Nowicka, Malgorzata, Hilton, Laura K., Ashton-Key, Margaret, Hargreaves, Chantal E., Lee, Chern, Foxall, Russell, Carter, Matthew J., Beers, Stephen A., Potter, Kathleen N., Bolen, Christopher R., Klein, Christian, Knapp, Andrea, Mir, Farheen, Rose-Zerilli, Matthew, Burton, Cathy, Klapper, Wolfram, Scott, David W., Sehn, Laurie H., Vitolo, Umberto, Martelli, Maurizio, Trneny, Marek, Rushton, Christopher K., Slack, Graham W., Farinha, Pedro, Strefford, Jonathan C., Oestergaard, Mikkel Z., Morin, Ryan D., Cragg, Mark S.
Published in Blood advances (10.08.2021)
Published in Blood advances (10.08.2021)
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Journal Article
Prognostic Impact of Germ-Line FCGR2A (H131R), FCGR3A (F158V), and FCGR2B (I232T) Single Nucleotide Polymorphisms in Lymphoma Patients Treated with Obinutuzumab or Rituximab in Combination with Chemotherapy: Results from the Phase III GALLIUM and GOYA Clinical Trials
Strefford, Jonathan C, Nowicka, Malgorzata, Hargreaves, Chantal, Iriyama, Chisako, Latham, Kate V, Ganderton, Rosalind, Parker, Helen, Potter, Kathleen N, Knapp, Andrea, Mir, Farheen, Rose-Zerilli, Matthew JJ, Burton, Cathy, Hiddemann, Wolfgang, Klapper, Wolfram, Sehn, Laurie H, Vitolo, Umberto, Martelli, Maurizio, Trněný, Marek, Davies, Andrew, Cragg, Mark C, Oestergaard, Mikkel Z
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
HIF activation enhances Fc[gamma]RIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy
Müller, Kri T. J, French, Ruth R, Beers, Stephen A, Carter, Matthew J, Oldham, Robert J, Foxall, Russell B, Smith, Rosanna C. G, Cragg, Mark S, Liu, Rena, Cleary, Kirstie L. S, Roghanian, Ali, Murray, Tom, Douglas, James, James, Sonya, Stopforth, Richard J, Ottensmeier, Christian H, Hargreaves, Chantal E, Booth, Steven G, Dahal, Lekh N, Markham, Hannah, Cutress, Ramsey I, Ghorbani, Mohammadmersad, Chee, Serena J, Kemp, Robert S, Longley, Jemma, Macari, Sofia, Strefford, Jonathan C, Glennie, Martin J, Hussain, Khiyam, Frendéus, Bjorn, Thirdborough, Stephen M
Published in Journal of experimental & clinical cancer research (07.04.2022)
Published in Journal of experimental & clinical cancer research (07.04.2022)
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Journal Article
Genomic Dissection of the Fcγ Receptor Region in the Context of Monoclonal Antibody Therapy
Hargreaves, Chantal, Iriyama, Chisako, Rose-Zerilli, Matthew JJ, Lee, Charlotte, Potter, Kathleen, Ganderton, Rosalind, Hussain, Khiyam, Machado, Lee, Hollox, Edward, Coupland, Sarah E, Stackpole, Michael, Oates, Melanie, Pettitt, Andrew R., Cragg, Mark, Strefford, Jonathan C
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Abstract PO-26: Prognostic significance of Fc gamma receptor IIB expression in the response of previously untreated diffuse large B-cell lymphomas to anti-CD20 monoclonal antibodies: Differing impact of rituximab and obinutuzumab
Hilton, Laura K., Nowicka, Malgorzata, Ashton-Key, Margaret, Hargreaves, Chantal E., Lee, Chern, Foxall, Russell, Carter, Matthew J., Beers, Stephen A., Potter, Kathleen N., Bolen, Christopher R., Klein, Christian, Knapp, Andrea, Mir, Farheen, Rose-Zerilli, Matthew, Burton, Cathy, Klapper, Wolfram, Scott, David W., Sehn, Laurie H., Vitolo, Umberto, Martelli, Maurizio, Trneny, Marek, Slack, Graham W., Farinha, Pedro, Strefford, Jonathan C., Oestergaard, Mikkel Z., Morin, Ryan D., Cragg, Mark S.
Published in Blood cancer discovery (01.11.2020)
Published in Blood cancer discovery (01.11.2020)
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