Development of Oxidative Stress by Cytochrome P450 Induction in Rodents Is Selective for Barbiturates and Related to Loss of Pyridine Nucleotide-dependent Protective Systems
Dostalek, Miroslav, Hardy, Klarissa D., Milne, Ginger L., Morrow, Jason D., Chen, Chi, Gonzalez, Frank J., Gu, Jun, Ding, Xinxin, Johnson, Delinda A., Johnson, Jeffrey A., Martin, Martha V., Guengerich, F. Peter
Published in The Journal of biological chemistry (20.06.2008)
Published in The Journal of biological chemistry (20.06.2008)
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In Vivo Oxidative Damage in Rats Is Associated with Barbiturate Response but Not Other Cytochrome P450 Inducers
Dostalek, Miroslav, Brooks, Joshua D, Hardy, Klarissa D, Milne, Ginger L, Moore, Megan M, Sharma, Sameer, Morrow, Jason D, Guengerich, F Peter
Published in Molecular pharmacology (01.12.2007)
Published in Molecular pharmacology (01.12.2007)
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Isoprostane Generation and Function
Milne, Ginger L, Yin, Huiyong, Hardy, Klarissa D, Davies, Sean S, Roberts, L. Jackson
Published in Chemical reviews (12.10.2011)
Published in Chemical reviews (12.10.2011)
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Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib
Ho, Han Kiat, Chan, James Chun Yip, Hardy, Klarissa D., Chan, Eric Chun Yong
Published in Drug metabolism reviews (01.02.2015)
Published in Drug metabolism reviews (01.02.2015)
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Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cells
Hardy, Klarissa D, Wahlin, Michelle D, Papageorgiou, Ioannis, Unadkat, Jashvant D, Rettie, Allan E, Nelson, Sidney D
Published in Drug metabolism and disposition (01.01.2014)
Published in Drug metabolism and disposition (01.01.2014)
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Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ12,14-prostaglandin J2-like compounds (deoxy-J2-isoprostanes) in vivo1
Hardy, Klarissa D., Cox, Brian E., Milne, Ginger L., Yin, Huiyong, Roberts, II L. Jackson
Published in Journal of lipid research (01.01.2011)
Published in Journal of lipid research (01.01.2011)
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Journal Article
Nonenzymatic free radical-catalyzed generation of 15-deoxy-Delta(12,14)-prostaglandin J(2)-like compounds (deoxy-J(2)-isoprostanes) in vivo
Hardy, Klarissa D., Cox, Brian E., Milne, Ginger L., Yin, Huiyong, Roberts, L. Jackson
Published in Journal of lipid research (01.01.2011)
Published in Journal of lipid research (01.01.2011)
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Journal Article
Formation and Metabolism of 15-Deoxy-Δ12,14Prostaglandin J2
Hardy, Klarissa D., Milne, Ginger L., Yin, Huiyong, Morrow, Jason D., Roberts, L. Jackson
Published in Free radical biology & medicine (01.01.2010)
Published in Free radical biology & medicine (01.01.2010)
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Journal Article
Development of Oxidative Stress by Cytochrome P450 Induction in Rodents Is Selective for Barbiturates and Related to Loss of Pyridine Nucleotide-dependent Protective SystemsS
Dostalek, Miroslav, Hardy, Klarissa D., Milne, Ginger L., Morrow, Jason D., Chen, Chi, Gonzalez, Frank J., Gu, Jun, Ding, Xinxin, Johnson, Delinda A., Johnson, Jeffrey A., Martin, Martha V., Guengerich, F. Peter
Published in The Journal of biological chemistry (20.06.2008)
Published in The Journal of biological chemistry (20.06.2008)
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Journal Article
Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo
Hardy, Klarissa D, Cox, Brian E, Milne, Ginger L, Yin, Huiyong, Roberts, 2nd, L Jackson
Published in Journal of lipid research (01.01.2011)
Published in Journal of lipid research (01.01.2011)
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