An accessible pharmacodynamic transcriptional biomarker for notch target engagement
Tanis, K Q, Podtelezhnikov, A A, Blackman, S C, Hing, J, Railkar, R A, Lunceford, J, Klappenbach, J A, Wei, B, Harman, A, Camargo, L M, Shah, S, Finney, E M, Hardwick, J S, Loboda, A, Watters, J, Bergstrom, D A, Demuth, T, Herman, G A, Strack, P R, Iannone, R
Published in Clinical pharmacology and therapeutics (01.04.2016)
Published in Clinical pharmacology and therapeutics (01.04.2016)
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Toxicity of oxysterols to human monocyte-macrophages
Clare, Katharine, Hardwick, Simon J., Carpenter, Keri L.H., Weeratunge, Nishanthi, Mitchinson, Malcolm J.
Published in Atherosclerosis (01.11.1995)
Published in Atherosclerosis (01.11.1995)
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Changes in elemental concentrations are associated with early stages of apoptosis in human monocyte-macrophages exposed to oxidized low-density lipoprotein: an X-ray microanalytical study
Skepper, Jeremy N., Karydis, Ioannis, Garnett, Matthew R., Hegyi, Laszlo, Hardwick, Simon J., Warley, Alice, Mitchinson, Malcolm J., Cary, Nat R. B.
Published in The Journal of pathology (01.05.1999)
Published in The Journal of pathology (01.05.1999)
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Rapamycin-Modulated Transcription Defines the Subset of Nutrient-Sensitive Signaling Pathways Directly Controlled by the Tor Proteins
Hardwick, James S., Kuruvilla, Finny G., Tong, Jeffrey K., Shamji, Alykhan F., Schreiber, Stuart L.
Published in Proceedings of the National Academy of Sciences - PNAS (21.12.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (21.12.1999)
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Protein Phosphatase 2A Interacts with the 70-kDa S6 Kinase and Is Activated by Inhibition of FKBP12-Rapamycin-Associated Protein
Peterson, Randall T., Desai, Bimal N., Hardwick, James S., Schreiber, Stuart L.
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.1999)
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N047B: NCCTG phase II trial of vorinostat (suberoylanilide hydroxamic acid) in recurrent glioblastoma multiforme (GBM)
Galanis, E., Jaeckle, K. A., Maurer, M. J., Reid, J. M., Ames, M. M., Giannini, C., Hardwick, J. S., Moore, D. F., Zwiebel, J. A., Buckner, J. C.
Published in Journal of clinical oncology (20.06.2007)
Published in Journal of clinical oncology (20.06.2007)
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Adenosine accumulation as an indicator of cell-specific toxicity in rat lung slices
Skamarauskas, J.T., Hardwick, S.J., Upshall, D.G., Cohen, G.M.
Published in Toxicology in vitro (01.10.1995)
Published in Toxicology in vitro (01.10.1995)
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Conference Proceeding
Paracetamol toxicity and its prevention by cytoprotection with iloprost
Davies, D S, Fawthrop, D J, Nasseri-Sina, P, Wilson, J W, Hardwick, S J, Boobis, A R
Published in Toxicology letters (01.12.1992)
Published in Toxicology letters (01.12.1992)
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Changes in vimentin in human macrophages during apoptosis induced by oxidised low density lipoprotein
Müller, Karin, Dulku, Simon, Hardwick, Simon J, Skepper, Jeremy N, Mitchinson, Malcolm J
Published in Atherosclerosis (01.05.2001)
Published in Atherosclerosis (01.05.2001)
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Conference Proceeding
Cell death in atherosclerotic plaques
Mitchinson, M J, Hardwick, S J, Bennett, M R
Published in Current opinion in lipidology (01.10.1996)
Published in Current opinion in lipidology (01.10.1996)
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The presence of apoptotic cells in human atherosclerotic lesions
Hegyi, L, Hardwick, S J, Mitchinson, M J, Skepper, J N
Published in The American journal of pathology (01.01.1997)
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Published in The American journal of pathology (01.01.1997)
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Activation of the Lck Tyrosine-protein Kinase by the Binding of the Tip Protein of Herpesvirus Saimiri in the Absence of Regulatory Tyrosine Phosphorylation
Hartley, D A, Hurley, T R, Hardwick, J S, Lund, T C, Medveczky, P G, Sefton, B M
Published in The Journal of biological chemistry (16.07.1999)
Published in The Journal of biological chemistry (16.07.1999)
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A Novel Lung Slice System with Compromised Antioxidant Defenses
Hardwick, Simon J., Adam, Aishah, Smith, Lewis L., Cohen, Gerald M.
Published in Environmental health perspectives (01.04.1990)
Published in Environmental health perspectives (01.04.1990)
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