Characterisation of a soft elastomer poly(glycerol sebacate) designed to match the mechanical properties of myocardial tissue
Chen, Qi-Zhi, Bismarck, Alexander, Hansen, Ulrich, Junaid, Sarah, Tran, Michael Q, Harding, Siân E, Ali, Nadire N, Boccaccini, Aldo R
Published in Biomaterials (01.01.2008)
Published in Biomaterials (01.01.2008)
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Use of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes in Preclinical Cancer Drug Cardiotoxicity Testing: A Scientific Statement From the American Heart Association
Gintant, Gary, Burridge, Paul, Gepstein, Lior, Harding, Sian, Herron, Todd, Hong, Charles, Jalife, José, Wu, Joseph C
Published in Circulation research (25.10.2019)
Published in Circulation research (25.10.2019)
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Journal Article
Hierarchical statistical techniques are necessary to draw reliable conclusions from analysis of isolated cardiomyocyte studies
Sikkel, Markus B, Francis, Darrel P, Howard, James, Gordon, Fabiana, Rowlands, Christina, Peters, Nicholas S, Lyon, Alexander R, Harding, Sian E, MacLeod, Kenneth T
Published in Cardiovascular research (01.12.2017)
Published in Cardiovascular research (01.12.2017)
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Journal Article
Remodelling of adult cardiac tissue subjected to physiological and pathological mechanical load in vitro
Pitoulis, Fotios G, Nunez-Toldra, Raquel, Xiao, Ke, Kit-Anan, Worrapong, Mitzka, Saskia, Jabbour, Richard J, Harding, Sian E, Perbellini, Filippo, Thum, Thomas, de Tombe, Pieter P, Terracciano, Cesare M
Published in Cardiovascular research (21.02.2022)
Published in Cardiovascular research (21.02.2022)
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Journal Article
Auxetic Cardiac Patches with Tunable Mechanical and Conductive Properties toward Treating Myocardial Infarction
Kapnisi, Michaella, Mansfield, Catherine, Marijon, Camille, Guex, Anne Geraldine, Perbellini, Filippo, Bardi, Ifigeneia, Humphrey, Eleanor J., Puetzer, Jennifer L., Mawad, Damia, Koutsogeorgis, Demosthenes C., Stuckey, Daniel J., Terracciano, Cesare M., Harding, Sian E., Stevens, Molly M.
Published in Advanced functional materials (24.05.2018)
Published in Advanced functional materials (24.05.2018)
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Journal Article
An elastomeric patch derived from poly(glycerol sebacate) for delivery of embryonic stem cells to the heart
Chen, Qi-Zhi, Ishii, Hikaru, Thouas, George A, Lyon, Alexander R, Wright, Jamie S, Blaker, Jonny J, Chrzanowski, Wojciech, Boccaccini, Aldo R, Ali, Nadire N, Knowles, Jonathan C, Harding, Siân E
Published in Biomaterials (01.05.2010)
Published in Biomaterials (01.05.2010)
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Journal Article
Redox Regulation of Cardiac ASK1 (Apoptosis Signal-Regulating Kinase 1) Controls p38-MAPK (Mitogen-Activated Protein Kinase) and Orchestrates Cardiac Remodeling to Hypertension
Meijles, Daniel N, Cull, Joshua J, Markou, Thomais, Cooper, Susanna T.E, Haines, Zoe H.R, Fuller, Stephen J, O’Gara, Peter, Sheppard, Mary N, Harding, Sian E, Sugden, Peter H, Clerk, Angela
Published in Hypertension (Dallas, Tex. 1979) (01.10.2020)
Published in Hypertension (Dallas, Tex. 1979) (01.10.2020)
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Journal Article
β₂-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation
Nikolaev, Viacheslav O, Moshkov, Alexey, Lyon, Alexander R, Miragoli, Michele, Novak, Pavel, Paur, Helen, Lohse, Martin J, Korchev, Yuri E, Harding, Sian E, Gorelik, Julia
Published in Science (American Association for the Advancement of Science) (26.03.2010)
Published in Science (American Association for the Advancement of Science) (26.03.2010)
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Journal Article
Immunomodulatory interventions in myocardial infarction and heart failure: a systematic review of clinical trials and meta-analysis of IL-1 inhibition
Panahi, Mona, Papanikolaou, Angelos, Torabi, Azam, Zhang, Ji-Gang, Khan, Habib, Vazir, Ali, Hasham, Muneer G, Cleland, John G F, Rosenthal, Nadia A, Harding, Sian E, Sattler, Susanne
Published in Cardiovascular research (01.09.2018)
Published in Cardiovascular research (01.09.2018)
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Journal Article
Modelling the interaction between stem cells derived cardiomyocytes patches and host myocardium to aid non-arrhythmic engineered heart tissue design
Fassina, Damiano, Costa, Caroline M, Longobardi, Stefano, Karabelas, Elias, Plank, Gernot, Harding, Sian E, Niederer, Steven A
Published in PLoS computational biology (01.04.2022)
Published in PLoS computational biology (01.04.2022)
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Journal Article
Cross-Priming Dendritic Cells Exacerbate Immunopathology After Ischemic Tissue Damage in the Heart
Forte, Elvira, Perkins, Bryant, Sintou, Amalia, Kalkat, Harkaran S, Papanikolaou, Angelos, Jenkins, Catherine, Alsubaie, Mashael, Chowdhury, Rasheda A, Duffy, Theodore M, Skelly, Daniel A, Branca, Jane, Bellahcene, Mohamed, Schneider, Michael D, Harding, Sian E, Furtado, Milena B, Ng, Fu Siong, Hasham, Muneer G, Rosenthal, Nadia, Sattler, Susanne
Published in Circulation (New York, N.Y.) (23.02.2021)
Published in Circulation (New York, N.Y.) (23.02.2021)
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Journal Article
Biomimetic electromechanical stimulation to maintain adult myocardial slices in vitro
Watson, Samuel A, Duff, James, Bardi, Ifigeneia, Zabielska, Magdalena, Atanur, Santosh S, Jabbour, Richard J, Simon, André, Tomas, Alejandra, Smolenski, Ryszard T, Harding, Sian E, Perbellini, Filippo, Terracciano, Cesare M
Published in Nature communications (15.05.2019)
Published in Nature communications (15.05.2019)
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Journal Article
Loss of T-tubules and Other Changes to Surface Topography in Ventricular Myocytes from Failing Human and Rat Heart
Lyon, Alexander R., MacLeod, Ken T., Zhang, Yanjun, Garcia, Edwin, Kanda, Gaelle Kikonda, Lab, Max J., Korchev, Yuri E., Harding, Sian E., Gorelik, Julia, Marks, Andrew R.
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2009)
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Journal Article
Stress (Takotsubo) cardiomyopathy-a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning
Lyon, Alexander R, Rees, Paul SC, Prasad, Sanjay, Poole-Wilson, Philip A, Harding, Sian E
Published in Nature clinical practice cardiovascular medicine (01.01.2008)
Published in Nature clinical practice cardiovascular medicine (01.01.2008)
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Journal Article
Circulating microRNAs predispose to takotsubo syndrome following high-dose adrenaline exposure
Couch, Liam S, Fiedler, Jan, Chick, Giles, Clayton, Rory, Dries, Eef, Wienecke, Laura M, Fu, Lu, Fourre, Jerome, Pandey, Pragati, Derda, Anselm A, Wang, Brian X, Jabbour, Richard, Shanmuganathan, Mayooran, Wright, Peter, Lyon, Alexander R, Terracciano, Cesare M, Thum, Thomas, Harding, Sian E
Published in Cardiovascular research (22.06.2022)
Published in Cardiovascular research (22.06.2022)
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Journal Article
MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
Fiedler, Lorna R., Chapman, Kathryn, Xie, Min, Maifoshie, Evie, Jenkins, Micaela, Golforoush, Pelin Arabacilar, Bellahcene, Mohamed, Noseda, Michela, Faust, Dörte, Jarvis, Ashley, Newton, Gary, Paiva, Marta Abreu, Harada, Mutsuo, Stuckey, Daniel J., Song, Weihua, Habib, Josef, Narasimhan, Priyanka, Aqil, Rehan, Sanmugalingam, Devika, Yan, Robert, Pavanello, Lorenzo, Sano, Motoaki, Wang, Sam C., Sampson, Robert D., Kanayaganam, Sunthar, Taffet, George E., Michael, Lloyd H., Entman, Mark L., Tan, Tse-Hua, Harding, Sian E., Low, Caroline M.R., Tralau-Stewart, Catherine, Perrior, Trevor, Schneider, Michael D.
Published in Cell stem cell (04.04.2019)
Published in Cell stem cell (04.04.2019)
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Journal Article
Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Encapsulating Bioactive Hydrogels Improve Rat Heart Function Post Myocardial Infarction
Chow, Andre, Stuckey, Daniel J., Kidher, Emaddin, Rocco, Mark, Jabbour, Richard J., Mansfield, Catherine A., Darzi, Ara, Harding, Sian E., Stevens, Molly M., Athanasiou, Thanos
Published in Stem cell reports (14.11.2017)
Published in Stem cell reports (14.11.2017)
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Journal Article
Quantifying the Release of Biomarkers of Myocardial Necrosis from Cardiac Myocytes and Intact Myocardium
Marjot, Jack, Kaier, Thomas E, Martin, Eva D, Reji, Shiney S, Copeland, O'Neal, Iqbal, Mohammed, Goodson, Bob, Hamren, Sarah, Harding, Sian E, Marber, Michael S
Published in Clinical chemistry (Baltimore, Md.) (01.05.2017)
Published in Clinical chemistry (Baltimore, Md.) (01.05.2017)
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Journal Article
The effect of microgrooved culture substrates on calcium cycling of cardiac myocytes derived from human induced pluripotent stem cells
Rao, Christopher, Prodromakis, Themistoklis, Kolker, Ljudmila, Chaudhry, Umar A.R, Trantidou, Tatiana, Sridhar, Arun, Weekes, Claire, Camelliti, Patrizia, Harding, Sian E, Darzi, Ara, Yacoub, Magdi H, Athanasiou, Thanos, Terracciano, Cesare M
Published in Biomaterials (01.03.2013)
Published in Biomaterials (01.03.2013)
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