Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening
Wellaway, Christopher R, Amans, Dominique, Bamborough, Paul, Barnett, Heather, Bit, Rino A, Brown, Jack A, Carlson, Neil R, Chung, Chun-wa, Cooper, Anthony W. J, Craggs, Peter D, Davis, Robert P, Dean, Tony W, Evans, John P, Gordon, Laurie, Harada, Isobel L, Hirst, David J, Humphreys, Philip G, Jones, Katherine L, Lewis, Antonia J, Lindon, Matthew J, Lugo, Dave, Mahmood, Mahnoor, McCleary, Scott, Medeiros, Patricia, Mitchell, Darren J, O’Sullivan, Michael, Le Gall, Armelle, Patel, Vipulkumar K, Patten, Chris, Poole, Darren L, Shah, Rishi R, Smith, Jane E, Stafford, Kayleigh A. J, Thomas, Pamela J, Vimal, Mythily, Wall, Ian D, Watson, Robert J, Wellaway, Natalie, Yao, Gang, Prinjha, Rab K
Published in Journal of medicinal chemistry (23.01.2020)
Published in Journal of medicinal chemistry (23.01.2020)
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BET bromodomain inhibitors show anti-papillomavirus activity in vitro and block CRPV wart growth in vivo
Morse, Mary A., Balogh, Karla K., Brendle, Sarah A., Campbell, Colin A., Chen, Mao X., Furze, Rebecca C., Harada, Isobel L., Holyer, Ian D., Kumar, Umesh, Lee, Kevin, Prinjha, Rab K., Rüdiger, Martin, Seal, Jonathan T., Taylor, Simon, Witherington, Jason, Christensen, Neil D.
Published in Antiviral research (01.06.2018)
Published in Antiviral research (01.06.2018)
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