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Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2018)
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Published in Biochemical and biophysical research communications (29.01.2017)
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Cancer with low cathepsin D levels is susceptible to vacuolar (H+)‐ATPase inhibition
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Published in PloS one (07.12.2017)
Published in PloS one (07.12.2017)
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A selective androgen receptor modulator SARM‐2f activates androgen receptor, increases lean body mass, and suppresses blood lipid levels in cynomolgus monkeys
Morimoto, Megumi, Yamaoka, Masuo, Hara, Takahito
Published in Pharmacology research & perspectives (01.02.2020)
Published in Pharmacology research & perspectives (01.02.2020)
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HARA, Takahito, MIYAZAKI, Hideyo, LEE, Aram, TRAN, Chau P, REITER, Robert E
Published in Cancer research (Chicago, Ill.) (15.02.2008)
Published in Cancer research (Chicago, Ill.) (15.02.2008)
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Cabozantinib inhibits AXL- and MET-dependent cancer cell migration induced by growth-arrest-specific 6 and hepatocyte growth factor
Hara, Takahito, Kimura, Akiko, Miyazaki, Tohru, Tanaka, Hiroshi, Morimoto, Megumi, Nakai, Katsuhiko, Soeda, Junpei
Published in Biochemistry and biophysics reports (01.03.2020)
Published in Biochemistry and biophysics reports (01.03.2020)
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Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors
Okegawa, Takatsugu, Morimoto, Megumi, Nishizawa, Satoru, Kitazawa, Satoshi, Honda, Kohei, Araki, Hideo, Tamura, Toshiya, Ando, Ayumi, Satomi, Yoshinori, Nutahara, Kikuo, Hara, Takahito
Published in EBioMedicine (01.05.2017)
Published in EBioMedicine (01.05.2017)
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Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs) Part III: Discovery of 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2f as a clinical candidate
Aikawa, Katsuji, Asano, Moriteru, Ono, Koji, Habuka, Noriyuki, Yano, Jason, Wilson, Keith, Fujita, Hisashi, Kandori, Hitoshi, Hara, Takahito, Morimoto, Megumi, Santou, Takashi, Yamaoka, Masuo, Nakayama, Masaharu, Hasuoka, Atsushi
Published in Bioorganic & medicinal chemistry (01.07.2017)
Published in Bioorganic & medicinal chemistry (01.07.2017)
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Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part I
Aikawa, Katsuji, Miyawaki, Toshio, Hitaka, Takenori, Imai, Yumi N., Hara, Takahito, Miyazaki, Junichi, Yamaoka, Masuo, Kusaka, Masami, Kanzaki, Naoyuki, Tasaka, Akihiro, Shiraishi, Mitsuru, Yamamoto, Satoshi
Published in Bioorganic & medicinal chemistry (15.05.2015)
Published in Bioorganic & medicinal chemistry (15.05.2015)
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Corrigendum to “Cabozantinib inhibits AXL- and MET-dependent cancer cell migration induced by growth-arrest-specific 6 and hepatocyte growth factor” [Biochem. Biophys. Rep. 21 (2020) 100726]
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Published in Biochemistry and biophysics reports (01.12.2020)
Published in Biochemistry and biophysics reports (01.12.2020)
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Design, synthesis, and biological evaluation of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists
Yamamoto, Satoshi, Tomita, Naoki, Suzuki, Yuri, Suzaki, Tomohiko, Kaku, Tomohiro, Hara, Takahito, Yamaoka, Masuo, Kanzaki, Naoyuki, Hasuoka, Atsushi, Baba, Atsuo, Ito, Mitsuhiro
Published in Bioorganic & medicinal chemistry (01.04.2012)
Published in Bioorganic & medicinal chemistry (01.04.2012)
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Design, synthesis, and biological evaluation of 4-phenylpyrrole derivatives as novel androgen receptor antagonists
Yamamoto, Satoshi, Matsunaga, Nobuyuki, Hitaka, Takenori, Yamada, Masami, Hara, Takahito, Miyazaki, Junichi, Santou, Takashi, Kusaka, Masami, Yamaoka, Masuo, Kanzaki, Naoyuki, Furuya, Shuichi, Tasaka, Akihiro, Hamamura, Kazumasa, Ito, Mitsuhiro
Published in Bioorganic & medicinal chemistry (01.01.2012)
Published in Bioorganic & medicinal chemistry (01.01.2012)
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C17,20-Lyase inhibitors I. Structure-based de novo design and SAR study of C17,20-lyase inhibitors
MATSUNAGA, Nobuyuki, KAKU, Tomohiro, TASAKA, Akihiro, ITOH, Fumio, TANAKA, Toshimasa, HARA, Takahito, MIKI, Hiroshi, IWASAKI, Masahiko, AONO, Tetsuya, YAMAOKA, Masuo, KUSAKA, Masami
Published in Bioorganic & medicinal chemistry (01.05.2004)
Published in Bioorganic & medicinal chemistry (01.05.2004)
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