Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR
Hao, Zongbing, Liu, Liu, Tao, Zhouteng, Wang, Rui, Ren, Haigang, Sun, Hongyang, Lin, Zixuan, Zhang, Zhixiong, Mu, Chenchen, Zhou, Jiawei, Wang, Guanghui
Published in Nature communications (02.07.2019)
Published in Nature communications (02.07.2019)
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Journal Article
Cereblon suppresses the formation of pathogenic protein aggregates in a p62-dependent manner
Zhou, Liang, Hao, Zongbing, Wang, Guanghui, Xu, Guoqiang
Published in Human molecular genetics (15.02.2018)
Published in Human molecular genetics (15.02.2018)
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Journal Article
Bioinformatics and network-based screening and discovery of potential molecular targets and small molecular drugs for breast cancer
Alam, Md Shahin, Sultana, Adiba, Sun, Hongyang, Wu, Jin, Guo, Fanfan, Li, Qing, Ren, Haigang, Hao, Zongbing, Zhang, Yi, Wang, Guanghui
Published in Frontiers in pharmacology (20.09.2022)
Published in Frontiers in pharmacology (20.09.2022)
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Journal Article
TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion
Xia, Qin, Wang, Hongfeng, Hao, Zongbing, Fu, Cheng, Hu, Qingsong, Gao, Feng, Ren, Haigang, Chen, Dong, Han, Junhai, Ying, Zheng, Wang, Guanghui
Published in The EMBO journal (18.01.2016)
Published in The EMBO journal (18.01.2016)
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Journal Article
DJ‐1 regulates tyrosine hydroxylase expression through CaMKKβ/CaMKIV/CREB1 pathway in vitro and in vivo
Xu, Xingyun, Wang, Rui, Hao, Zongbing, Wang, Guanghui, Mu, Chenchen, Ding, Jianqing, Sun, Wanping, Ren, Haigang
Published in Journal of cellular physiology (01.02.2020)
Published in Journal of cellular physiology (01.02.2020)
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Journal Article
Disrupted phase behavior of FUS underlies poly-PR-induced DNA damage in amyotrophic lateral sclerosis
Wang, Yixin, Liu, Liu, Chen, Hui, Yang, Yinxue, Mu, Chenchen, Ren, Haigang, Liu, Yanli, Yu, Liqiang, Fang, Qi, Wang, Guanghui, Hao, Zongbing
Published in Human molecular genetics (12.12.2023)
Published in Human molecular genetics (12.12.2023)
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Journal Article
Loss of VAPB Regulates Autophagy in a Beclin 1-Dependent Manner
Wu, Dan, Hao, Zongbing, Ren, Haigang, Wang, Guanghui
Published in Neuroscience bulletin (01.12.2018)
Published in Neuroscience bulletin (01.12.2018)
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Journal Article
Inhibition of EHMT1/2 rescues synaptic damage and motor impairment in a PD mouse model
Zhang, Zhixiong, Wang, Rui, Zhou, Hui, Wu, Dan, Cao, Yifan, Zhang, Chuang, Sun, Hongyang, Mu, Chenchen, Hao, Zongbing, Ren, Haigang, Wang, Nana, Yu, Shuang, Zhang, Jingzhong, Tao, Mengdan, Wang, Can, Liu, Yan, Liu, Liu, Liu, Yanli, Zang, Jianye, Wang, Guanghui
Published in Cellular and molecular life sciences : CMLS (01.12.2024)
Published in Cellular and molecular life sciences : CMLS (01.12.2024)
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Journal Article
The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates
Pu, Mei, Tai, Yusi, Yuan, Luyang, Zhang, Yu, Guo, Huijie, Hao, Zongbing, Chen, Jing, Qi, Xinming, Wang, Guanghui, Tao, Zhouteng, Ren, Jin
Published in Cellular and molecular life sciences : CMLS (01.09.2022)
Published in Cellular and molecular life sciences : CMLS (01.09.2022)
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Journal Article
C9orf72 associates with inactive Rag GTPases and regulates mTORC1‐mediated autophagosomal and lysosomal biogenesis
Wang, Mingmei, Wang, Hongfeng, Tao, Zhouteng, Xia, Qin, Hao, Zongbing, Prehn, Jochen H. M., Zhen, Xuechu, Wang, Guanghui, Ying, Zheng
Published in Aging cell (01.04.2020)
Published in Aging cell (01.04.2020)
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Journal Article
Tyrosine hydroxylase down-regulation after loss of Abelson helper integration site 1 (AHI1) promotes depression via the circadian clock pathway in mice
Guo, Dongkai, Zhang, Shun, Sun, Hongyang, Xu, Xingyun, Hao, Zongbing, Mu, Chenchen, Xu, Xingshun, Wang, Guanghui, Ren, Haigang
Published in The Journal of biological chemistry (06.04.2018)
Published in The Journal of biological chemistry (06.04.2018)
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Journal Article
Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Hao, Zongbing, Wang, Rui, Ren, Haigang, Wang, Guanghui
Published in Neuroscience bulletin (01.09.2020)
Published in Neuroscience bulletin (01.09.2020)
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Journal Article
Glucosylceramide accumulation in microglia triggers STING-dependent neuroinflammation and neurodegeneration in mice
Wang, Rui, Sun, Hongyang, Cao, Yifan, Zhang, Zhixiong, Chen, Yajing, Wang, Xiying, Liu, Lele, Wu, Jin, Xu, Hao, Wu, Dan, Mu, Chenchen, Hao, Zongbing, Qin, Song, Ren, Haigang, Han, Junhai, Fang, Ming, Wang, Guanghui
Published in Science signaling (26.03.2024)
Published in Science signaling (26.03.2024)
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Journal Article
TARDBP/TDP-43 regulates autophagy in both MTORC1-dependent and MTORC1-independent manners
Ying, Zheng, Xia, Qin, Hao, Zongbing, Xu, Delai, Wang, Mingmei, Wang, Hongfeng, Wang, Guanghui
Published in Autophagy (02.04.2016)
Published in Autophagy (02.04.2016)
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Journal Article
Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis
Wang, Rui, Xu, Xingyun, Hao, Zongbing, Zhang, Shun, Wu, Dan, Sun, Hongyang, Mu, Chenchen, Ren, Haigang, Wang, Guanghui
Published in Neuroscience bulletin (01.10.2019)
Published in Neuroscience bulletin (01.10.2019)
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