Depleting MET-Expressing Tumor Cells by ADCC Provides a Therapeutic Advantage over Inhibiting HGF/MET Signaling
Hultberg, Anna, Morello, Virginia, Huyghe, Leander, De Jonge, Natalie, Blanchetot, Christophe, Hanssens, Valérie, De Boeck, Gitte, Silence, Karen, Festjens, Els, Heukers, Raimond, Roux, Benjamin, Lamballe, Fabienne, Ginestier, Christophe, Charafe-Jauffret, Emmanuelle, Maina, Flavio, Brouckaert, Peter, Saunders, Michael, Thibault, Alain, Dreier, Torsten, de Haard, Hans, Michieli, Paolo
Published in Cancer research (Chicago, Ill.) (15.08.2015)
Published in Cancer research (Chicago, Ill.) (15.08.2015)
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Journal Article
Dual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy
Godar, Marie, Morello, Virginia, Sadi, Ava, Hultberg, Anna, De Jonge, Natalie, Basilico, Cristina, Hanssens, Valérie, Saunders, Michael, Lambrecht, Bart N., El Khattabi, Mohamed, de Haard, Hans, Michieli, Paolo, Blanchetot, Christophe
Published in Scientific reports (22.08.2016)
Published in Scientific reports (22.08.2016)
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Journal Article
Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans
Ulrichts, Peter, Guglietta, Antonio, Dreier, Torsten, van Bragt, Tonke, Hanssens, Valérie, Hofman, Erik, Vankerckhoven, Bernhardt, Verheesen, Peter, Ongenae, Nicolas, Lykhopiy, Valentina, Enriquez, F Javier, Cho, JunHaeng, Ober, Raimund J, Ward, E Sally, de Haard, Hans, Leupin, Nicolas
Published in The Journal of clinical investigation (01.10.2018)
Published in The Journal of clinical investigation (01.10.2018)
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Journal Article
GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson's Disease and Lewy Body Dementia
Maetzler, Walter, Deleersnijder, Willy, Hanssens, Valérie, Bernard, Alice, Brockmann, Kathrin, Marquetand, Justus, Wurster, Isabel, Rattay, Tim W, Roncoroni, Lorenzo, Schaeffer, Eva, Lerche, Stefanie, Apel, Anja, Deuschle, Christian, Berg, Daniela
Published in PloS one (03.03.2016)
Published in PloS one (03.03.2016)
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Journal Article
Four individually druggable MET hotspots mediate HGF-driven tumor progression
Basilico, Cristina, Hultberg, Anna, Blanchetot, Christophe, de Jonge, Natalie, Festjens, Els, Hanssens, Valérie, Osepa, Sjudry-Ilona, De Boeck, Gitte, Mira, Alessia, Cazzanti, Manuela, Morello, Virginia, Dreier, Torsten, Saunders, Michael, de Haard, Hans, Michieli, Paolo
Published in The Journal of clinical investigation (01.07.2014)
Published in The Journal of clinical investigation (01.07.2014)
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Journal Article
The NHance® Mutation-Equipped Anti-MET Antibody ARGX-111 Displays Increased Tissue Penetration and Anti-Tumor Activity in Advanced Cancer Patients
Aftimos, Philippe, Rolfo, Christian, Rottey, Sylvie, Barthélémy, Philippe, Borg, Christophe, Park, Keunchil, Oh, Do-Youn, Kim, Sang-We, De Jonge, Natalie, Hanssens, Valérie, Zwanenpoel, Karen, Molthoff, Carla, Vugts, Daniëlle, Dreier, Torsten, Verheesen, Peter, van Dongen, Guus A.M.S., Jacobs, Julie, Van Rompaey, Luc, Hultberg, Anna, Michieli, Paolo, Pauwels, Patrick, Fung, Samson, Thibault, Alain, de Haard, Hans, Leupin, Nicolas, Awada, Ahmad
Published in Biomedicines (10.06.2021)
Published in Biomedicines (10.06.2021)
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Journal Article
Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans
Ulrichts, Peter, Guglietta, Antonio, Dreier, Torsten, Bragt, Tonke van, Hanssens, Valérie, Hofman, Erik, Vankerckhoven, Bernhardt, Verheesen, Peter, Ongenae, Nicolas, Lykhopiy, Valentina, Enriquez, F Javier, Cho, JunHaeng, Ober, Raimund J, Ward, E Sally, de Haard, Hans, Leupin, Nicolas
Published in The Journal of clinical investigation (01.10.2018)
Published in The Journal of clinical investigation (01.10.2018)
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Journal Article
Abstract LB-330: Four individually druggable Met hotspots mediate HGF-driven tumor progression
Hultberg, Anna, Basilico, Cristina, Blanchetot, Cristophe, Jonge, Natalie D., Hanssens, Valérie, Boeck, Gitte D., Mira, Alessia, Cazzanti, Manuela, Morello, Virginia, Dreier, Torsten, Saunders, Michael, Haard, Hans D., Michieli, Paolo
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
2D-CEX-FcRn-MS to Study Structure/Function Relation of mAb Charge Variants
Verscheure, Liesa, Vandenheede, Isabel, De Rore, Eline, Meersseman, Mabelle, Hanssens, Valerie, Meerschaert, Kris, Stals, Hilde, Sandra, Pat, Lynen, Frederic, Borgions, Filip, Sandra, Koen
Published in Analytical chemistry (Washington) (29.10.2024)
Published in Analytical chemistry (Washington) (29.10.2024)
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Journal Article
Exploring the learning needs of clinicians in Belgium and Sweden regarding prone positioning and skin damage prevention: A qualitative study
Fourie, Anika, Karlberg-Traav, Malin, Dahlberg, Karuna, Hanssens, Valerie, Smet, Steven, Jaensson, Maria, Beeckman, Dimitri
Published in Nurse education today (01.09.2023)
Published in Nurse education today (01.09.2023)
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Journal Article
Using an Elastomeric Skin Protectant to Manage Donor Site Wounds of Split-thickness Skin Grafts: A Case Series
Peters, Ellen, Hanssens, Valerie, De Henau, Melissa, Dupont, Yamina, Spinnael, Jeannine, Giunta, Gabriele, Zeltzer, Assaf, De Baerdemaeker, Randy, Hamdi, Moustapha
Published in Advances in skin & wound care (01.09.2023)
Published in Advances in skin & wound care (01.09.2023)
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Journal Article
Case Report of Two Patients With COVID-19 and Sacral Pressure Injuries Associated with Pyoderma Gangrenosum
Elkhatib, Rania, Giunta, Gabriele, Hanssens, Valerie, Kapila, Ayush, De Baerdemaeker, Randy, Zeltzer, Assaf, Hamdi, Moustapha
Published in Advances in skin & wound care (01.08.2021)
Published in Advances in skin & wound care (01.08.2021)
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Journal Article
A Rare Case of KID Syndrome: The Use of Hydrosurgery and Strategies for Antiseptic Wound Care
Kapila, Ayush K, De Baerdemaeker, Randy, Bakal, Fadi, Hanssens, Valerie, Spinnael, Jeannine, Hendrickx, Benoit, Zeltzer, Assaf, Hamdi, Moustapha
Published in Advances in skin & wound care (01.10.2019)
Published in Advances in skin & wound care (01.10.2019)
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Journal Article
A phase I, first-in-human study of argx-111, a monoclonal antibody targeting c-met in patients with solid tumors
Aftimos, Philippe G., Barthelemy, Philippe, Rolfo, Christian D., Hanssens, Valerie, De Jonge, Natalie, Silence, Karen, Dreier, Torsten, de Haard, Hans, Peeters, Marc, Thibault, Alain, Awada, Ahmad
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
ARGX-111 shows activity in MET-amplified patients in a phase-I study and in preclinical models of myeloid-derived suppressor cell (MDSC) depletion in the tumor microenvironment
Rolfo, Christian Diego, Aftimos, Philippe Georges, Pallandre, Jean-Rene, Morello, Virginia, Bouard, Adeline, Cazzanti, Manuela, Barthelemy, Philippe, Rottey, Sylvie, Awada, Ahmad, Hanssens, Valerie, De Jonge, Natalie, Van Rompaey, Luc, Fung, Samson Sau-Sing, Michieli, Paolo, Borg, Christophe
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
Antibodies to IL-24
Jean-Christophe Renauld, Laure Dumoutier, Erik Hofman, Michael Saunders, Christophe Frederic Jerome Blanchetot, Valérie Hanssens
Year of Publication 10.05.2017
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Year of Publication 10.05.2017
Patent
GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson's Disease and Lewy Body Dementia: e0149349
Maetzler, Walter, Deleersnijder, Willy, Hanssens, Valerie, Bernard, Alice, Brockmann, Kathrin, Marquetand, Justus, Wurster, Isabel, Rattay, Tim W, Roncoroni, Lorenzo, Schaeffer, Eva
Published in PloS one (01.03.2016)
Published in PloS one (01.03.2016)
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Journal Article
ANTIBODIES TO IL-24
DUMOUTIER, Laure, HANSSENS, Valérie, BLANCHETOT, Christophe, HOFMAN, Erik, SAUNDERS, Michael, RENAULD, Jean-Christophe
Year of Publication 03.11.2016
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Year of Publication 03.11.2016
Patent