Fatty acid 16:4(n‐3) stimulates a GPR120‐induced signaling cascade in splenic macrophages to promote chemotherapy resistance
Houthuijzen, Julia M., Oosterom, Ilse, Hudson, Brian D., Hirasawa, Akira, Daenen, Laura G. M., McLean, Chelsea M., Hansen, Steffen V. F., Jaarsveld, Marijn T. M., Peeper, Daniel S., Sadatmand, Sahar Jafari, Roodhart, Jeanine M. L., Lest, Chris H. A., Ulven, Trond, Ishihara, Kenji, Milligan, Graeme, Voest, Emile E.
Published in The FASEB journal (01.05.2017)
Published in The FASEB journal (01.05.2017)
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Journal Article
Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes
Christiansen, Elisabeth, Hansen, Steffen V. F, Urban, Christian, Hudson, Brian D, Wargent, Edward T, Grundmann, Manuel, Jenkins, Laura, Zaibi, Mohamed, Stocker, Claire J, Ullrich, Susanne, Kostenis, Evi, Kassack, Matthias U, Milligan, Graeme, Cawthorne, Michael A, Ulven, Trond
Published in ACS medicinal chemistry letters (09.05.2013)
Published in ACS medicinal chemistry letters (09.05.2013)
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Journal Article
Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity
Azevedo, Carlos M. G, Watterson, Kenneth R, Wargent, Ed T, Hansen, Steffen V. F, Hudson, Brian D, Kępczyńska, Małgorzata A, Dunlop, Julia, Shimpukade, Bharat, Christiansen, Elisabeth, Milligan, Graeme, Stocker, Claire J, Ulven, Trond
Published in Journal of medicinal chemistry (13.10.2016)
Published in Journal of medicinal chemistry (13.10.2016)
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Journal Article
Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4
Watterson, Kenneth R, Hansen, Steffen V F, Hudson, Brian D, Alvarez-Curto, Elisa, Raihan, Sheikh Zahir, Azevedo, Carlos M G, Martin, Gabriel, Dunlop, Julia, Yarwood, Stephen J, Ulven, Trond, Milligan, Graeme
Published in Molecular pharmacology (01.06.2017)
Published in Molecular pharmacology (01.06.2017)
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Journal Article
Discovery of a Potent and Selective Free Fatty Acid Receptor 1 Agonist with Low Lipophilicity and High Oral Bioavailability
Christiansen, Elisabeth, Due-Hansen, Maria E, Urban, Christian, Grundmann, Manuel, Schmidt, Johannes, Hansen, Steffen V. F, Hudson, Brian D, Zaibi, Mohamed, Markussen, Stine B, Hagesaether, Ellen, Milligan, Graeme, Cawthorne, Michael A, Kostenis, Evi, Kassack, Matthias U, Ulven, Trond
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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Journal Article
Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy
Hansen, Steffen V. F, Christiansen, Elisabeth, Urban, Christian, Hudson, Brian D, Stocker, Claire J, Due-Hansen, Maria E, Wargent, Ed T, Shimpukade, Bharat, Almeida, Reinaldo, Ejsing, Christer S, Cawthorne, Michael A, Kassack, Matthias U, Milligan, Graeme, Ulven, Trond
Published in Journal of medicinal chemistry (24.03.2016)
Published in Journal of medicinal chemistry (24.03.2016)
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Journal Article
A protocol for amide bond formation with electron deficient amines and sterically hindered substrates
Due-Hansen, Maria E., Pandey, Sunil K., Christiansen, Elisabeth, Andersen, Rikke, Hansen, Steffen V. F., Ulven, Trond
Published in Organic & biomolecular chemistry (14.01.2016)
Published in Organic & biomolecular chemistry (14.01.2016)
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Journal Article
Correction: Controlled generation and use of CO in flow
Hansen, Steffen V. F, Wilson, Zoe E, Ulven, Trond, Ley, Steven V
Published in Reaction chemistry & engineering (31.05.2016)
Published in Reaction chemistry & engineering (31.05.2016)
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Pharmacological Tool Compounds for the Free Fatty Acid Receptor 4 (FFA4/GPR120)
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Book Chapter
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GPR120 조절제로서의 테트라하이드로-벤조[d]아제핀 유도체
BRVAR MATJAZ, RIGBY AARON, SMYTH DON, BROWN JANE, HANSEN STEFFEN V. F, CONNOLLY STEPHEN, MILNE GAVIN, SHIMPUKADE BHARAT, THOMAS GERARD, ULVEN TROND
Year of Publication 20.12.2019
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Year of Publication 20.12.2019
Patent
Controlled generation and use of CO in flow
Hansen, Steffen V. F., Wilson, Zoe E., Ulven, Trond, Ley, Steven V.
Published in Reaction chemistry & engineering (01.01.2016)
Published in Reaction chemistry & engineering (01.01.2016)
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Journal Article
ChemInform Abstract: A Protocol for Amide Bond Formation with Electron Deficient Amines and Sterically Hindered Substrates
Due‐Hansen, Maria E., Pandey, Sunil K., Christiansen, Elisabeth, Andersen, Rikke, Hansen, Steffen V. F., Ulven, Trond
Published in ChemInform (01.04.2016)
Published in ChemInform (01.04.2016)
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Journal Article
A protocol for amide bond formation with electron deficient amines and sterically hindered substratesElectronic supplementary information (ESI) available: Synthetic procedures, compound characterization, NMR spectra. See DOI: 10.1039/c5ob02129d
Due-Hansen, Maria E, Pandey, Sunil K, Christiansen, Elisabeth, Andersen, Rikke, Hansen, Steffen V. F, Ulven, Trond
Year of Publication 23.12.2015
Year of Publication 23.12.2015
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Journal Article
Controlled generation and use of CO in flowAdditional data related to this publication is available at the University of Cambridge Institutional Data Repository (https://www.repository.cam.ac.uk/handle/1810/253530).Electronic supplementary information (ESI) available: Full experimental details, characterisation of products and supporting NMR spectra. See DOI: 10.1039/c6re00020g
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TETRAHYDRO-BENZO[D]AZEPINE DERIVATIVES AS GPR120 MODULATORS
CONNOLLY, Stephen, THOMAS, Gerard, ULVEN, Trond, BROWN, Jane, HANSEN, Steffen V. F, SMYTH, Don, MILNE, Gavin, BRVAR, Matjaz, SHIMPUKADE, Bharat, RIGBY, Aaron
Year of Publication 30.03.2022
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Year of Publication 30.03.2022
Patent
Tetrahydro-benzo[d]azepine derivatives as GPR120 modulators
Smyth, Don, Rigby, Aaron, Brown, Jane, Ulven, Trond, Milne, Gavin, Shimpukade, Bharat, Brvar, Matjaz, Thomas, Gerard, Connolly, Stephen, Hansen, Steffen V. F
Year of Publication 11.01.2022
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Year of Publication 11.01.2022
Patent
TETRAHYDRO-BENZO[D]AZEPINE DERIVATIVES AS GPR120 MODULATORS
CONNOLLY, Stephen, THOMAS, Gerard, ULVEN, Trond, BROWN, Jane, SMYTH, Don, HANSEN, Steffen, V., F, MILNE, Gavin, BRVAR, Matjaz, SHIMPUKADE, Bharat, RIGBY, Aaron
Year of Publication 05.02.2020
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Year of Publication 05.02.2020
Patent
TETRAHYDRO-BENZO[D]AZEPINE DERIVATIVES AS GPR120 MODULATORS
THOMAS, GERARD, BRVAR, MATJAZ, HANSEN, STEFFEN V. F, MILNE, GAVIN, SHIMPUKADE, BHARAT, CONNOLLY, STEPHEN, SMYTH, DON, RIGBY, AARON, ULVEN, TROND, BROWN, JANE
Year of Publication 27.09.2018
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Year of Publication 27.09.2018
Patent