Dysregulation of Escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection
Nagamatsu, Kanna, Hannan, Thomas J, Guest, Randi L, Kostakioti, Maria, Hadjifrangiskou, Maria, Binkley, Jana, Dodson, Karen, Raivio, Tracy L, Hultgren, Scott J
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2015)
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Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection
Hannan, Thomas J., Totsika, Makrina, Mansfield, Kylie J., Moore, Kate H., Schembri, Mark A., Hultgren, Scott J.
Published in FEMS microbiology reviews (01.05.2012)
Published in FEMS microbiology reviews (01.05.2012)
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Journal Article
Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection
Schwartz, Drew J, Conover, Matt S, Hannan, Thomas J, Hultgren, Scott J
Published in PLoS pathogens (01.01.2015)
Published in PLoS pathogens (01.01.2015)
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Journal Article
A FimH Inhibitor Prevents Acute Bladder Infection and Treats Chronic Cystitis Caused by Multidrug-Resistant Uropathogenic Escherichia coli ST131
Totsika, Makrina, Kostakioti, Maria, Hannan, Thomas J., Upton, Mathew, Beatson, Scott A., Janetka, James W., Hultgren, Scott J., Schembri, Mark A.
Published in The Journal of infectious diseases (15.09.2013)
Published in The Journal of infectious diseases (15.09.2013)
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Journal Article
Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections
O'Brien, Valerie P, Hannan, Thomas J, Nielsen, Hailyn V, Hultgren, Scott J
Published in Microbiology spectrum (01.02.2016)
Published in Microbiology spectrum (01.02.2016)
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Journal Article
Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections
Schreiber, 4th, Henry L, Conover, Matt S, Chou, Wen-Chi, Hibbing, Michael E, Manson, Abigail L, Dodson, Karen W, Hannan, Thomas J, Roberts, Pacita L, Stapleton, Ann E, Hooton, Thomas M, Livny, Jonathan, Earl, Ashlee M, Hultgren, Scott J
Published in Science translational medicine (22.03.2017)
Published in Science translational medicine (22.03.2017)
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Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection
Lin, Ann E, Beasley, Federico C, Olson, Joshua, Keller, Nadia, Shalwitz, Robert A, Hannan, Thomas J, Hultgren, Scott J, Nizet, Victor
Published in PLoS pathogens (01.04.2015)
Published in PLoS pathogens (01.04.2015)
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Journal Article
Secretory leukocyte protease inhibitor protects against severe urinary tract infection in mice
Rosen, Anne L, Lint, Michael A, Voelker, Dayne H, Gilbert, Nicole M, Tomera, Christopher P, Santiago-Borges, Jesús, Wallace, Meghan A, Hannan, Thomas J, Burnham, Carey-Ann D, Hultgren, Scott J, Kau, Andrew L
Published in mBio (14.02.2024)
Published in mBio (14.02.2024)
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Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome
Russell, Seongmi K., Harrison, Jessica K., Olson, Benjamin S., Lee, Hyung Joo, O’Brien, Valerie P., Xing, Xiaoyun, Livny, Jonathan, Yu, Lu, Roberson, Elisha D. O., Bomjan, Rajdeep, Fan, Changxu, Sha, Marina, Estfanous, Shady, Amer, Amal O., Colonna, Marco, Stappenbeck, Thaddeus S., Wang, Ting, Hannan, Thomas J., Hultgren, Scott J.
Published in Nature microbiology (01.05.2023)
Published in Nature microbiology (01.05.2023)
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Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women
Worby, Colin J., Schreiber, Henry L., Straub, Timothy J., van Dijk, Lucas R., Bronson, Ryan A., Olson, Benjamin S., Pinkner, Jerome S., Obernuefemann, Chloe L. P., Muñoz, Vanessa L., Paharik, Alexandra E., Azimzadeh, Philippe N., Walker, Bruce J., Desjardins, Christopher A., Chou, Wen-Chi, Bergeron, Karla, Chapman, Sinéad B., Klim, Aleksandra, Manson, Abigail L., Hannan, Thomas J., Hooton, Thomas M., Kau, Andrew L., Lai, H. Henry, Dodson, Karen W., Hultgren, Scott J., Earl, Ashlee M.
Published in Nature microbiology (01.05.2022)
Published in Nature microbiology (01.05.2022)
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Journal Article
Subinhibitory antibiotic therapy alters recurrent urinary tract infection pathogenesis through modulation of bacterial virulence and host immunity
Goneau, Lee W, Hannan, Thomas J, MacPhee, Roderick A, Schwartz, Drew J, Macklaim, Jean M, Gloor, Gregory B, Razvi, Hassan, Reid, Gregor, Hultgren, Scott J, Burton, Jeremy P
Published in mBio (31.03.2015)
Published in mBio (31.03.2015)
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Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds through a Concerted β Strand Displacement Mechanism
Remaut, Han, Rose, Rebecca J., Hannan, Thomas J., Hultgren, Scott J., Radford, Sheena E., Ashcroft, Alison E., Waksman, Gabriel
Published in Molecular cell (23.06.2006)
Published in Molecular cell (23.06.2006)
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Distinguishing the Contribution of Type 1 Pili from That of Other QseB-Misregulated Factors when QseC Is Absent during Urinary Tract Infection
KOSTAKIOTI, Maria, HADJIFRANGISKOU, Maria, CUSUMANO, Corinne K, HANNAN, Thomas J, JANETKA, James W, HULTGREN, Scott J
Published in Infection and Immunity (01.08.2012)
Published in Infection and Immunity (01.08.2012)
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