The nucleolus: an emerging target for cancer therapy
Hein, Nadine, Hannan, Katherine M, George, Amee J, Sanij, Elaine, Hannan, Ross D
Published in Trends in molecular medicine (01.11.2013)
Published in Trends in molecular medicine (01.11.2013)
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Journal Article
Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
Bywater, Megan J., Poortinga, Gretchen, Sanij, Elaine, Hein, Nadine, Peck, Abigail, Cullinane, Carleen, Wall, Meaghan, Cluse, Leonie, Drygin, Denis, Anderes, Kenna, Huser, Nanni, Proffitt, Chris, Bliesath, Joshua, Haddach, Mustapha, Schwaebe, Michael K., Ryckman, David M., Rice, William G., Schmitt, Clemens, Lowe, Scott W., Johnstone, Ricky W., Pearson, Richard B., McArthur, Grant A., Hannan, Ross D.
Published in Cancer cell (10.07.2012)
Published in Cancer cell (10.07.2012)
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Journal Article
Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes
Wagner, Susan, Herrmannová, Anna, Hronová, Vladislava, Gunišová, Stanislava, Sen, Neelam D., Hannan, Ross D., Hinnebusch, Alan G., Shirokikh, Nikolay E., Preiss, Thomas, Valášek, Leoš Shivaya
Published in Molecular cell (20.08.2020)
Published in Molecular cell (20.08.2020)
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Journal Article
Dysregulation of the basal RNA polymerase transcription apparatus in cancer
Bywater, Megan J., Pearson, Richard B., McArthur, Grant A., Hannan, Ross D.
Published in Nature reviews. Cancer (01.05.2013)
Published in Nature reviews. Cancer (01.05.2013)
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Journal Article
Comprehensive translational profiling and STE AI uncover rapid control of protein biosynthesis during cell stress
Horvath, Attila, Janapala, Yoshika, Woodward, Katrina, Mahmud, Shafi, Cleynen, Alice, Gardiner, Elizabeth E, Hannan, Ross D, Eyras, Eduardo, Preiss, Thomas, Shirokikh, Nikolay E
Published in Nucleic acids research (09.05.2024)
Published in Nucleic acids research (09.05.2024)
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Journal Article
Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart
Foster, Simon R, Porrello, Enzo R, Purdue, Brooke, Chan, Hsiu-Wen, Voigt, Anja, Frenzel, Sabine, Hannan, Ross D, Moritz, Karen M, Simmons, David G, Molenaar, Peter, Roura, Eugeni, Boehm, Ulrich, Meyerhof, Wolfgang, Thomas, Walter G
Published in PloS one (15.05.2013)
Published in PloS one (15.05.2013)
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Journal Article
Targeting the nucleolus for cancer intervention
Quin, Jaclyn E., Devlin, Jennifer R., Cameron, Donald, Hannan, Kate M., Pearson, Richard B., Hannan, Ross D.
Published in Biochimica et biophysica acta (01.06.2014)
Published in Biochimica et biophysica acta (01.06.2014)
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Journal Article
A Novel Mouse Model of Atherosclerotic Plaque Instability for Drug Testing and Mechanistic/Therapeutic Discoveries Using Gene and MicroRNA Expression Profiling
Chen, Yung-Chih, Bui, Anh Viet, Diesch, Jeannine, Manasseh, Richard, Hausding, Christian, Rivera, Jennifer, Haviv, Izhak, Agrotis, Alex, Htun, Nay Min, Jowett, Jeremy, Hagemeyer, Christoph Eugen, Hannan, Ross D, Bobik, Alex, Peter, Karlheinz
Published in Circulation research (19.07.2013)
Published in Circulation research (19.07.2013)
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Journal Article
Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age
Ferreira, Rita, Schneekloth, Jr, John S, Panov, Konstantin I, Hannan, Katherine M, Hannan, Ross D
Published in Cells (Basel, Switzerland) (21.01.2020)
Published in Cells (Basel, Switzerland) (21.01.2020)
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Journal Article
Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers
Udugama, Maheshi, Sanij, Elaine, Voon, Hsiao P. J., Son, Jinbae, Hii, Linda, Henson, Jeremy D., Chan, F. Lyn, Chang, Fiona T. M., Liu, Yumei, Pearson, Richard B., Kalitsis, Paul, Mann, Jeffrey R., Collas, Philippe, Hannan, Ross D., Wong, Lee H.
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2018)
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Journal Article
Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells
Diesch, Jeannine, Sanij, Elaine, Gilan, Omer, Love, Christopher, Tran, Hoanh, Fleming, Nicholas I, Ellul, Jason, Amalia, Marcia, Haviv, Izhak, Pearson, Richard B, Tulchinsky, Eugene, Mariadason, John M, Sieber, Oliver M, Hannan, Ross D, Dhillon, Amardeep S
Published in PloS one (21.03.2014)
Published in PloS one (21.03.2014)
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Journal Article
A functional genetic screen defines the AKT-induced senescence signaling network
Chan, Keefe T., Blake, Shaun, Zhu, Haoran, Kang, Jian, Trigos, Anna S., Madhamshettiwar, Piyush B., Diesch, Jeannine, Paavolainen, Lassi, Horvath, Peter, Hannan, Ross D., George, Amee J., Sanij, Elaine, Hannan, Katherine M., Simpson, Kaylene J., Pearson, Richard B.
Published in Cell death and differentiation (01.02.2020)
Published in Cell death and differentiation (01.02.2020)
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Journal Article
Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth
DRYGIN, Denis, LIN, Amy, STREINER, Nicole, QUIN, Jaclyn E, SANIJ, Elaine, BYWATE, Megan J, HANNAN, Ross D, RYCKMAN, David, ANDERES, Kenna, RICE, William G, BLIESATH, Josh, HO, Caroline B, O'BRIEN, Sean E, PROFFITT, Chris, OMORI, Mayuko, HADDACH, Mustapha, SCHWAEBE, Michael K, SIDDIQUI-JAIN, Adam
Published in Cancer research (Chicago, Ill.) (15.02.2011)
Published in Cancer research (Chicago, Ill.) (15.02.2011)
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Journal Article
Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis
Kerry, Louise E, Pegg, Elaine E, Cameron, Donald P, Budzak, James, Poortinga, Gretchen, Hannan, Katherine M, Hannan, Ross D, Rudenko, Gloria
Published in PLoS neglected tropical diseases (06.03.2017)
Published in PLoS neglected tropical diseases (06.03.2017)
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Journal Article
First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study
Khot, Amit, Brajanovski, Natalie, Cameron, Donald P, Hein, Nadine, Maclachlan, Kylee H, Sanij, Elaine, Lim, John, Soong, John, Link, Emma, Blombery, Piers, Thompson, Ella R, Fellowes, Andrew, Sheppard, Karen E, McArthur, Grant A, Pearson, Richard B, Hannan, Ross D, Poortinga, Gretchen, Harrison, Simon J
Published in Cancer discovery (01.08.2019)
Published in Cancer discovery (01.08.2019)
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Journal Article
Regulation of rDNA transcription in response to growth factors, nutrients and energy
Kusnadi, Eric P., Hannan, Katherine M., Hicks, Rodney J., Hannan, Ross D., Pearson, Richard B., Kang, Jian
Published in Gene (01.02.2015)
Published in Gene (01.02.2015)
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Journal Article
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
Wong, Lee H, McGhie, James D, Sim, Marcus, Anderson, Melissa A, Ahn, Soyeon, Hannan, Ross D, George, Amee J, Morgan, Kylie A, Mann, Jeffrey R, Choo, K H Andy
Published in Genome research (01.03.2010)
Published in Genome research (01.03.2010)
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Journal Article