Development of a Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung Exposure in Humans Following Oral Administration of Ivermectin for COVID-19 Drug Repurposing
Jermain, Brian, Hanafin, Patrick O., Cao, Yanguang, Lifschitz, Adrian, Lanusse, Carlos, Rao, Gauri G.
Published in Journal of pharmaceutical sciences (01.12.2020)
Published in Journal of pharmaceutical sciences (01.12.2020)
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Journal Article
Insights Into Patient Variability During Ivacaftor-Lumacaftor Therapy in Cystic Fibrosis
Hanafin, Patrick O, Sermet-Gaudelus, Isabelle, Griese, Matthias, Kappler, Matthias, Ellemunter, Helmut, Schwarz, Carsten, Wilson, John, Tan, Marsha, Velkov, Tony, Rao, Gauri G, Schneider-Futschik, Elena K
Published in Frontiers in pharmacology (02.08.2021)
Published in Frontiers in pharmacology (02.08.2021)
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Journal Article
A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans
Hanafin, Patrick O., Jermain, Brian, Hickey, Anthony J., Kabanov, Alexander V., Kashuba, Angela DM, Sheahan, Timothy P., Rao, Gauri G.
Published in CPT: Pharmacometrics & Systems Pharmacology (01.02.2021)
Published in CPT: Pharmacometrics & Systems Pharmacology (01.02.2021)
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Journal Article
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Assessing the predictive performance of population pharmacokinetic models for intravenous polymyxin B in critically ill patients
Hanafin, Patrick O., Nation, Roger L., Scheetz, Marc H., Zavascki, Alexandre P., Sandri, Ana M., Kwa, Andrea L., Cherng, Benjamin P. Z., Kubin, Christine J., Yin, Michael T., Wang, Jiping, Li, Jian, Kaye, Keith S., Rao, Gauri G.
Published in CPT: pharmacometrics and systems pharmacology (01.12.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.12.2021)
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Journal Article
Proof‐of‐concept for incorporating mechanistic insights from multi‐omics analyses of polymyxin B in combination with chloramphenicol against Klebsiella pneumoniae
Hanafin, Patrick O., Abdul Rahim, Nusaibah, Sharma, Rajnikant, Cess, Colin G., Finley, Stacey D., Bergen, Phillip J., Velkov, Tony, Li, Jian, Rao, Gauri G.
Published in CPT: pharmacometrics and systems pharmacology (01.03.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.03.2023)
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Journal Article
Reapproaching Old Treatments: Considerations for PK/PD Studies on Phage Therapy for Bacterial Respiratory Infections
Schmalstig, Alan A, Freidy, Soha, Hanafin, Patrick O, Braunstein, Miriam, Rao, Gauri G
Published in Clinical pharmacology and therapeutics (01.06.2021)
Published in Clinical pharmacology and therapeutics (01.06.2021)
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Journal Article
Evaluation Strategies for Triple‐Drug Combinations against Carbapenemase‐Producing Klebsiella Pneumoniae in an In Vitro Hollow‐Fiber Infection Model
Garcia, Estefany, Diep, John K., Sharma, Rajnikant, Hanafin, Patrick O., Abboud, Cely S., Kaye, Keith S., Li, Jian, Velkov, Tony, Rao, Gauri G.
Published in Clinical pharmacology and therapeutics (01.04.2021)
Published in Clinical pharmacology and therapeutics (01.04.2021)
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Journal Article
A Systems-Based Analysis of Mono- and Combination Therapy for Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections
Luterbach, Courtney L., Qiu, Hongqiang, Hanafin, Patrick O., Sharma, Rajnikant, Piscitelli, Joseph, Lin, Feng-Chang, Ilomaki, Jenni, Cober, Eric, Salata, Robert A., Kalayjian, Robert C., Watkins, Richard R., Doi, Yohei, Kaye, Keith S., Nation, Roger L., Bonomo, Robert A., Landersdorfer, Cornelia B., van Duin, David, Rao, Gauri G.
Published in Antimicrobial agents and chemotherapy (18.10.2022)
Published in Antimicrobial agents and chemotherapy (18.10.2022)
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Journal Article
A population pharmacokinetic model of polymyxin B based on prospective clinical data to inform dosing in hospitalized patients
Hanafin, Patrick O., Kwa, Andrea, Zavascki, Alexandre P., Sandri, Ana Maria, Scheetz, Marc H., Kubin, Christine J., Shah, Jayesh, Cherng, Benjamin P.Z., Yin, Michael T., Wang, Jiping, Wang, Lu, Calfee, David P., Bolon, Maureen, Pogue, Jason M., Purcell, Anthony W., Nation, Roger L., Li, Jian, Kaye, Keith S., Rao, Gauri G.
Published in Clinical microbiology and infection (01.09.2023)
Published in Clinical microbiology and infection (01.09.2023)
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Journal Article
International society of Pharmacometrics Mentorship Program (IMP): feedback survey from the first cohort of mentor-mentee pairs
Hanafin, Patrick O., Murthy, Ananya, Marathe, Dhananjay, Diep, John K., Krishnatry, Anu Shilpa, Lon, Hoi-Kei, Shah, Dhaval K., Ait-Oudhia, Sihem, Rao, Gauri G.
Published in Journal of pharmacokinetics and pharmacodynamics (01.08.2023)
Published in Journal of pharmacokinetics and pharmacodynamics (01.08.2023)
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Journal Article