Enterically derived high-density lipoprotein restrains liver injury through the portal vein
Han, Yong-Hyun, Onufer, Emily J, Huang, Li-Hao, Sprung, Robert W, Davidson, W Sean, Czepielewski, Rafael S, Wohltmann, Mary, Sorci-Thomas, Mary G, Warner, Brad W, Randolph, Gwendalyn J
Published in Science (American Association for the Advancement of Science) (23.07.2021)
Published in Science (American Association for the Advancement of Science) (23.07.2021)
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Journal Article
RORα Induces KLF4-Mediated M2 Polarization in the Liver Macrophages that Protect against Nonalcoholic Steatohepatitis
Han, Yong-Hyun, Kim, Hyeon-Ji, Na, Hyelin, Nam, Min-Woo, Kim, Ju-Yeon, Kim, Jun-Seok, Koo, Seung-Hoi, Lee, Mi-Ock
Published in Cell reports (Cambridge) (05.07.2017)
Published in Cell reports (Cambridge) (05.07.2017)
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Journal Article
Hepatic TREM2 + macrophages express matrix metalloproteinases to control fibrotic scar formation
Lee, Kyeong-Jin, An, Seungchan, Kim, Mi-Yeon, Kim, Sun Myoung, Jeong, Won-Il, Ko, Hyun-Jeong, Yang, Yoon Mee, Noh, Minsoo, Han, Yong-Hyun
Published in Immunology and cell biology (01.03.2023)
Published in Immunology and cell biology (01.03.2023)
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Lipid absorption and overall intestinal lymphatic transport are impaired following partial small bowel resection in mice
Onufer, Emily J, Czepielewski, Rafael S, Han, Yong-Hyun, Courtney, Cathleen M, Sutton, Stephanie, Sescleifer, Anne, Randolph, Gwendalyn J, Warner, Brad W
Published in Scientific reports (07.07.2022)
Published in Scientific reports (07.07.2022)
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Journal Article
Liver-specific deletion of RORα aggravates diet-induced nonalcoholic steatohepatitis by inducing mitochondrial dysfunction
Kim, Hyeon-Ji, Han, Yong-Hyun, Na, Hyelin, Kim, Ju-Yeon, Kim, Taewook, Kim, Hye-Jin, Shin, Chanseok, Lee, Jung Weon, Lee, Mi-Ock
Published in Scientific reports (22.11.2017)
Published in Scientific reports (22.11.2017)
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Journal Article
Disruption of IL-18 signaling via engineered IL-18BP biologics alleviates experimental cholestatic liver disease
Kim, Dong-Hyun, Lee, Kyeong-Jin, Park, JinJoo, Chi, Susan, Han, Jaekyu, Bang, Yewon, Kim, Sun-Mi, Kang, Seung Goo, Cha, Sang-Hoon, Han, Yong-Hyun
Published in Biomedicine & pharmacotherapy (01.11.2023)
Published in Biomedicine & pharmacotherapy (01.11.2023)
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Journal Article
Specialized Proresolving Mediators for Therapeutic Interventions Targeting Metabolic and Inflammatory Disorders
Han, Yong-Hyun, Lee, Kyeongjin, Saha, Abhirup, Han, Juhyeong, Choi, Haena, Noh, Minsoo, Lee, Yun-Hee, Lee, Mi-Ock
Published in Biomolecules & therapeutics (01.09.2021)
Published in Biomolecules & therapeutics (01.09.2021)
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Journal Article
RORα suppresses interleukin-6-mediated hepatic acute phase response
Kim, Ju-Yeon, Han, Yong-Hyun, Nam, Min-Woo, Kim, Hyeon-Ji, Lee, Mi-Ock
Published in Scientific reports (13.08.2019)
Published in Scientific reports (13.08.2019)
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Journal Article
RORα Enhances Lysosomal Acidification and Autophagic Flux in the Hepatocytes
Kim, Hyeon‐Ji, Han, Yong‐Hyun, Kim, Ju‐Yeon, Lee, Mi‐Ock
Published in Hepatology communications (01.12.2021)
Published in Hepatology communications (01.12.2021)
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Journal Article
A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis
Han, Yong-Hyun, Shin, Kyong-Oh, Kim, Ju-Yeon, Khadka, Daulat B, Kim, Hyeon-Ji, Lee, Yong-Moon, Cho, Won-Jea, Cha, Ji-Young, Lee, Bong-Jin, Lee, Mi-Ock
Published in The Journal of clinical investigation (01.04.2019)
Published in The Journal of clinical investigation (01.04.2019)
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Syntheses of the ω-pyridinium-containing very-long-chain ceramides PyrCer(24:1(15Z)) and PyrCer(24:0) and their anticancer activity
Ko, Ju Young, Kim, Mi-Yeon, Jeon, Ji-Yoon, Jung, Jin Yi, Han, Yong-Hyun, Kim, Jae Hyun
Published in Bioorganic & medicinal chemistry letters (15.01.2024)
Published in Bioorganic & medicinal chemistry letters (15.01.2024)
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Panaxydol extracted from Panax ginseng inhibits NLRP3 inflammasome activation to ameliorate NASH-induced liver injury
Kim, Mi-Yeon, Jeong, Birang, Lee, Geun-Shik, Jeon, Hongjun, Yang, Yoon Mee, Yang, Heejung, Han, Yong-Hyun
Published in International immunopharmacology (15.02.2024)
Published in International immunopharmacology (15.02.2024)
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Journal Article
Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor
Czepielewski, Rafael S., Erlich, Emma C., Onufer, Emily J., Young, Shannon, Saunders, Brian T., Han, Yong-Hyun, Wohltmann, Mary, Wang, Peter L., Kim, Ki-Wook, Kumar, Shashi, Hsieh, Chyi-Song, Scallan, Joshua P., Yang, Ying, Zinselmeyer, Bernd H., Davis, Michael J., Randolph, Gwendalyn J.
Published in Immunity (Cambridge, Mass.) (14.12.2021)
Published in Immunity (Cambridge, Mass.) (14.12.2021)
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Journal Article
RORα regulates hepatic lipolysis by inducing transcriptional expression of PNPLA3 in mice
Han, Yong-Hyun, Kim, Hyeon-Ji, Lee, Mi-Ock
Published in Molecular and cellular endocrinology (15.02.2021)
Published in Molecular and cellular endocrinology (15.02.2021)
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Journal Article
RORα autoregulates its transcription via MLL4-associated enhancer remodeling in the liver
Han, Yong-Hyun, Kim, Hyeon-Ji, Choi, Haena, Lee, Seunghee, Lee, Mi-Ock
Published in Life sciences (1973) (01.09.2020)
Published in Life sciences (1973) (01.09.2020)
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Journal Article
RORα decreases oxidative stress through the induction of SOD2 and GPx1 expression and thereby protects against nonalcoholic steatohepatitis in mice
Han, Yong-Hyun, Kim, Hyeon-Ji, Kim, Eun-Jin, Kim, Kyu-Seo, Hong, Suckchang, Park, Hyeung-Geun, Lee, Mi-Ock
Published in Antioxidants & redox signaling (20.11.2014)
Published in Antioxidants & redox signaling (20.11.2014)
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