PROTACs Targeting MLKL Protect Cells from Necroptosis
Rathje, Oliver H., Perryman, Lara, Payne, Richard J., Hamprecht, Dieter W.
Published in Journal of medicinal chemistry (24.08.2023)
Published in Journal of medicinal chemistry (24.08.2023)
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Journal Article
BI 456906: Discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy
Zimmermann, Tina, Thomas, Leo, Baader-Pagler, Tamara, Haebel, Peter, Simon, Eric, Reindl, Wolfgang, Bajrami, Besnik, Rist, Wolfgang, Uphues, Ingo, Drucker, Daniel J., Klein, Holger, Santhanam, Rakesh, Hamprecht, Dieter, Neubauer, Heike, Augustin, Robert
Published in Molecular metabolism (Germany) (01.12.2022)
Published in Molecular metabolism (Germany) (01.12.2022)
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Journal Article
Stabilization of the open conformation οf insulin‐regulated aminopeptidase by a novel substrate‐selective small‐molecule inhibitor
Mpakali, Anastasia, Georgaki, Galateia, Buson, Alberto, Findlay, Alison D., Foot, Jonathan S., Mauvais, Francois‐Xavier, Endert, Peter, Giastas, Petros, Hamprecht, Dieter W., Stratikos, Efstratios
Published in Protein science (01.09.2024)
Published in Protein science (01.09.2024)
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Journal Article
An efficient one-pot two catalyst system in the construction of 2-substituted benzimidazoles: synthesis of benzimidazo[1,2-c] quinazolines
Cimarelli, Cristina, Di Nicola, Matteo, Diomedi, Simone, Giovannini, Riccardo, Hamprecht, Dieter, Properzi, Roberta, Sorana, Federico, Marcantoni, Enrico
Published in Organic & biomolecular chemistry (01.01.2015)
Published in Organic & biomolecular chemistry (01.01.2015)
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Journal Article
An activity‐based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti‐fibrotic therapeutic strategies
Findlay, Alison, Turner, Craig, Schilter, Heidi, Deodhar, Mandar, Zhou, Wenbin, Perryman, Lara, Foot, Jonathan, Zahoor, Amna, Yao, Yimin, Hamilton, Ross, Brock, Mary, Raso, Christina, Stolp, Jessica, Galati, Marie, Hamprecht, Dieter, Charlton, Brett, Jarolimek, Wolfgang
Published in Clinical and translational medicine (01.11.2021)
Published in Clinical and translational medicine (01.11.2021)
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Journal Article
Synthesis of 2-Substituted Benzofurans and Indoles Using Functionalized Titanium Benzylidene Reagents on Solid Phase
Macleod, Calum, McKiernan, Gordon J, Guthrie, Emma J, Farrugia, Louis J, Hamprecht, Dieter W, Macritchie, Jackie, Hartley, Richard C
Published in Journal of organic chemistry (24.01.2003)
Published in Journal of organic chemistry (24.01.2003)
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Journal Article
The antimicrobial natural product chuangxinmycin and Some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase
Brown, Murray J., Carter, Paul S., Fenwick, Ashley E., Fosberry, Andrew P., Hamprecht, Dieter W., Hibbs, Martin J., Jarvest, Richard L., Mensah, Lucy, Milner, Peter H., O'Hanlon, Peter J., Pope, Andrew J., Richardson, Christine M., West, Andrew, Witty, David R.
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
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Journal Article
Dess−Martin Periodinane Oxidation of Alcohols in the Presence of Stabilized Phosphorus Ylides: A Convenient Method for the Homologation of Alcohols via Unstable Aldehydes
Barrett, Anthony G. M, Hamprecht, Dieter, Ohkubo, Mitsuru
Published in Journal of organic chemistry (26.12.1997)
Published in Journal of organic chemistry (26.12.1997)
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Journal Article
Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT6 receptor antagonists
AHMED, Mahmood, BRIGGS, Michael A, JOHNSON, Christopher N, MEDHURST, Andrew D, MITCHELL, Darren J, MOSS, Stephen F, POWLES, Jenifer, SEAL, Jon T, STEAN, Tania O, STEMP, Geoffrey, THOMPSON, Mervyn, TRAIL, Brenda, BROMIDGE, Steven M, UPTON, Neil, WINBORN, Kim, WITTY, David R, BUCK, Tania, CAMPBELL, Lorraine, DEEKS, Nigel J, GARNER, Ashley, GORDON, Laurie, HAMPRECHT, Dieter W, HOLLAND, Vicky
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
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Journal Article
Unified Route to the Palmarumycin and Preussomerin Natural Products. Enantioselective Synthesis of (−)-Preussomerin G
Barrett, Anthony G. M, Blaney, Frank, Campbell, Andrew D, Hamprecht, Dieter, Meyer, Thorsten, White, Andrew J. P, Witty, David, Williams, David J
Published in Journal of organic chemistry (03.05.2002)
Published in Journal of organic chemistry (03.05.2002)
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Journal Article
Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues
Jarvest, Richard L, Armstrong, Sula A, Berge, John M, Brown, Pamela, Elder, John S, Brown, Murray J, Copley, Royston C.B, Forrest, Andrew K, Hamprecht, Dieter W, O'Hanlon, Peter J, Mitchell, Darren J, Rittenhouse, Stephen, Witty, David R
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
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Journal Article
The dual GCGR/GLP‐1R agonist survodutide: Biomarkers and pharmacological profiling for clinical candidate selection
Thomas, Leo, Martel, Eric, Rist, Wolfgang, Uphues, Ingo, Hamprecht, Dieter, Neubauer, Heike, Augustin, Robert
Published in Diabetes, obesity & metabolism (01.06.2024)
Published in Diabetes, obesity & metabolism (01.06.2024)
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Journal Article
Biosynthesis of the 2H-Azepine Alkaloid Chalciporone
Spiteller, Peter, Hamprecht, Dieter, Steglich, Wolfgang
Published in Journal of the American Chemical Society (23.05.2001)
Published in Journal of the American Chemical Society (23.05.2001)
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Journal Article
Iterative Cyclopropanation: A Concise Strategy for the Total Synthesis of the Hexacyclopropane Cholesteryl Ester Transfer Protein Inhibitor U-106305
Barrett, Anthony G. M, Hamprecht, Dieter, White, Andrew J. P, Williams, David J
Published in Journal of the American Chemical Society (17.09.1997)
Published in Journal of the American Chemical Society (17.09.1997)
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Journal Article
Synthesis and Characterization of Coronanes: Multicyclopropane-Fused Macrocyclic Arrays
Barrett, Anthony G. M, Hamprecht, Dieter, James, Rachel A, Ohkubo, Mitsuru, Procopiou, Panayiotis A, Toledo, Miguel A, White, Andrew J. P, Williams, David J
Published in Journal of organic chemistry (06.04.2001)
Published in Journal of organic chemistry (06.04.2001)
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Journal Article
Potent synthetic inhibitors of tyrosyl tRNA synthetase derived from C-pyranosyl analogues of SB-219383
Jarvest, Richard L, Berge, John M, Brown, Pamela, Hamprecht, Dieter W, McNair, David J, Mensah, Lucy, O'Hanlon, Peter J, Pope, Andrew J
Published in Bioorganic & medicinal chemistry letters (12.03.2001)
Published in Bioorganic & medicinal chemistry letters (12.03.2001)
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Journal Article
Inhibitors of bacterial tyrosyl tRNA synthetase: synthesis of four stereoisomeric analogues of the natural product SB-219383
Berge, John M, Copley, Royston C.B, Eggleston, Drake S, Hamprecht, Dieter W, Jarvest, Richard L, Mensah, Lucy M, O'Hanlon, Peter J, Pope, Andrew J
Published in Bioorganic & medicinal chemistry letters (21.08.2000)
Published in Bioorganic & medicinal chemistry letters (21.08.2000)
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Journal Article
ACYLATED GLUCAGON ANALOGUES
HAMPRECHT DIETER WOLFGANG, RIST WOLFGANG, RIBER DITTE, TOLBORG JAKOB LIND
Year of Publication 30.03.2022
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Year of Publication 30.03.2022
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