Quinol-4-ones as Steroid A-Ring Mimetics in Nonsteroidal Dissociated Glucocorticoid Agonists
Regan, John, Lee, Thomas W, Zindell, Renée M, Bekkali, Younes, Bentzien, Jörg, Gilmore, Thomas, Hammach, Abdelhakim, Kirrane, Thomas M, Kukulka, Alison J, Kuzmich, Daniel, Nelson, Richard M, Proudfoot, John R, Ralph, Mark, Pelletier, Josephine, Souza, Donald, Zuvela-Jelaska, Lijiljana, Nabozny, Gerald, Thomson, David S
Published in Journal of medicinal chemistry (28.12.2006)
Published in Journal of medicinal chemistry (28.12.2006)
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Journal Article
Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase
Hammach, Abdelhakim, Barbosa, Antonio, Gaenzler, Faith Corbo, Fadra, Tazmeen, Goldberg, Daniel, Hao, Ming-Hong, Kroe, Rachel R., Liu, Pingrong, Qian, Kevin C., Ralph, Mark, Sarko, Christopher, Soleymanzadeh, Fariba, Moss, Neil
Published in Bioorganic & medicinal chemistry letters (15.12.2006)
Published in Bioorganic & medicinal chemistry letters (15.12.2006)
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Journal Article
Isoquinolinone synthesis by SNAr reaction: a versatile route to imidazo[4,5-h]isoquinolin-9-ones
Snow, RJ, Butz, T, Hammach, A, Kapadia, S, Morwick, TM, Prokopowicz, AS, Takahashi, H, Tan, JD, Tschantz, MA, Wang, XJ
Published in Tetrahedron letters (14.10.2002)
Published in Tetrahedron letters (14.10.2002)
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Journal Article
Optimization of 2-Phenylaminoimidazo[4,5-h]isoquinolin-9-ones: Orally Active Inhibitors of lck Kinase
Goldberg, Daniel R, Butz, Tanja, Cardozo, Mario G, Eckner, Robert J, Hammach, Abdelhakim, Huang, Jessica, Jakes, Scott, Kapadia, Suresh, Kashem, Mohammed, Lukas, Susan, Morwick, Tina M, Panzenbeck, Maret, Patel, Usha, Pav, Susan, Peet, Gregory W, Peterson, Jeffrey D, Prokopowicz, Anthony S, Snow, Roger J, Sellati, Rosemarie, Takahashi, Hidenori, Tan, Jonathan, Tschantz, Matt A, Wang, Xiao-Jun, Wang, Yong, Wolak, John, Xiong, Pla, Moss, Neil
Published in Journal of medicinal chemistry (10.04.2003)
Published in Journal of medicinal chemistry (10.04.2003)
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Journal Article
Application of Ferrocenylalkyl Chiral Auxiliaries to Syntheses of Indolenine Alkaloids: Enantioselective Syntheses of Vincadifformine, ψ- and 20-epi-ψ-Vincadifformines, Tabersonine, Ibophyllidine, and Mossambine
Kuehne, Martin E., Bandarage, Upul K., Hammach, Abdelhakim, Li, Yun-Long, Wang, Tiansheng
Published in Journal of organic chemistry (03.04.1998)
Published in Journal of organic chemistry (03.04.1998)
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Journal Article
Isoquinolinone synthesis by S NAr reaction: a versatile route to imidazo[4,5- h]isoquinolin-9-ones
Snow, Roger J., Butz, Tanja, Hammach, Abdelhakim, Kapadia, Suresh, Morwick, Tina M., Prokopowicz, Anthony S., Takahashi, Hidenori, Tan, Jonathan D., Tschantz, Matt A., Wang, Xiao-Jun
Published in Tetrahedron letters (2002)
Published in Tetrahedron letters (2002)
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Journal Article
Synthesis of regioisomeric 6,9-(chlorofluoro)-substituted benzo[g]quinoline-5,10-diones, benzo[g]isoquinoline-5,10-diones and 6-chloro-9-fluorobenzo[g]quinoxaline-5,10-dione
Krapcho, AP, Gallagher, CE, Hammach, A, Ellis, M, Menta, E, Oliva, A
Published in Journal of heterocyclic chemistry (01.01.1997)
Published in Journal of heterocyclic chemistry (01.01.1997)
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Journal Article
Synthesis of 1,4-Dihydropyridines by Regioselective Additions of Benzylic Zinc Bromides to Pyridinium Salts and Their Aromatizations to 4-Benzylpyridines
Krapcho, A. Paul, Waterhouse, David J., Hammach, Abdelhakim, Di Domenico, Roberto, Menta, Ernesto, Oliva, Ambrogio, Spinelli, Silvano
Published in Synthetic communications (01.03.1997)
Published in Synthetic communications (01.03.1997)
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Journal Article
1,2,3-TRIAZOLAMIDDERIVATE ALS INHIBITOREN DER CYTOKINPRODUKTION
AUNGST, RONALD, COGAN, DEREK, GOLDBERG, DANIEL, HAMMACH, ABDELHAKIM, NETHERTON, MATTHEW
Year of Publication 15.03.2011
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Year of Publication 15.03.2011
Patent
1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKIE PRODUCTION
NETHERTON, MATTHEW RUSSELL, COGAN, DEREK, GOLDBERG, DANIEL R, HAMMACH, ABDELHAKIM, AUNGST, RONALD A., JR
Year of Publication 30.07.2013
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Year of Publication 30.07.2013
Patent
Synthesis of hydroxy-substituted aza-analogues of antitumor anthrapyrazoles
Krapcho, AP, Gallagher, CE, Hammach, A, Hacker, MP, Menta, E, Oliva, A, Di Domenico, R, Da Re, G, Lotto, A, Spinelli, S
Published in Journal of heterocyclic chemistry (01.07.1998)
Published in Journal of heterocyclic chemistry (01.07.1998)
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Journal Article
1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION
COGAN, DEREK, HAMMACH, ABDELHAKIM, NETHERTON, MATTHEW, RUSSELL, GOLDBERG, DANIEL, R, AUNGST, RONALD, A., JR
Year of Publication 09.03.2011
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Year of Publication 09.03.2011
Patent
Glucocorticoid, indazole, mimetics, methods of making them, pharmaceutical compositions, and uses thereof
BENTZIEN, JOERG MARTIN, MUGGE, INGO ANDREAS, BURKE, MICHAEL JASON, HAMMACH, ABDELHAKIM, THOMSON, DAVID S, RALPH, MARK STEPHEN, KOWALSKI, JENNIFER A
Year of Publication 27.05.2011
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Year of Publication 27.05.2011
Patent