Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis
Guttman-Yassky, Emma, Bissonnette, Robert, Ungar, Benjamin, Suárez-Fariñas, Mayte, Ardeleanu, Marius, Esaki, Hitokazu, Suprun, Maria, Estrada, Yeriel, Xu, Hui, Peng, Xiangyu, Silverberg, Jonathan I., Menter, Alan, Krueger, James G., Zhang, Rick, Chaudhry, Usman, Swanson, Brian, Graham, Neil M.H., Pirozzi, Gianluca, Yancopoulos, George D., D. Hamilton, Jennifer D.
Published in Journal of allergy and clinical immunology (01.01.2019)
Published in Journal of allergy and clinical immunology (01.01.2019)
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Journal Article
Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma
Rabe, Klaus F, Nair, Parameswaran, Brusselle, Guy, Maspero, Jorge F, Castro, Mario, Sher, Lawrence, Zhu, Hongjie, Hamilton, Jennifer D, Swanson, Brian N, Khan, Asif, Chao, Jingdong, Staudinger, Heribert, Pirozzi, Gianluca, Antoni, Christian, Amin, Nikhil, Ruddy, Marcella, Akinlade, Bolanle, Graham, Neil M.H, Stahl, Neil, Yancopoulos, George D, Teper, Ariel
Published in The New England journal of medicine (28.06.2018)
Published in The New England journal of medicine (28.06.2018)
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Journal Article
Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma
Castro, Mario, Corren, Jonathan, Pavord, Ian D, Maspero, Jorge, Wenzel, Sally, Rabe, Klaus F, Busse, William W, Ford, Linda, Sher, Lawrence, FitzGerald, J. Mark, Katelaris, Constance, Tohda, Yuji, Zhang, Bingzhi, Staudinger, Heribert, Pirozzi, Gianluca, Amin, Nikhil, Ruddy, Marcella, Akinlade, Bolanle, Khan, Asif, Chao, Jingdong, Martincova, Renata, Graham, Neil M.H, Hamilton, Jennifer D, Swanson, Brian N, Stahl, Neil, Yancopoulos, George D, Teper, Ariel
Published in The New England journal of medicine (28.06.2018)
Published in The New England journal of medicine (28.06.2018)
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Journal Article
The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies
Copin, Richard, Baum, Alina, Wloga, Elzbieta, Pascal, Kristen E., Giordano, Stephanie, Fulton, Benjamin O., Zhou, Anbo, Negron, Nicole, Lanza, Kathryn, Chan, Newton, Coppola, Angel, Chiu, Joyce, Ni, Min, Wei, Yi, Atwal, Gurinder S., Hernandez, Annabel Romero, Saotome, Kei, Zhou, Yi, Franklin, Matthew C., Hooper, Andrea T., McCarthy, Shane, Hamon, Sara, Hamilton, Jennifer D., Staples, Hilary M., Alfson, Kendra, Carrion, Ricardo, Ali, Shazia, Norton, Thomas, Somersan-Karakaya, Selin, Sivapalasingam, Sumathi, Herman, Gary A., Weinreich, David M., Lipsich, Leah, Stahl, Neil, Murphy, Andrew J., Yancopoulos, George D., Kyratsous, Christos A.
Published in Cell (22.07.2021)
Published in Cell (22.07.2021)
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Journal Article
Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases
Hamilton, Jennifer D., Harel, Sivan, Swanson, Brian N., Brian, William, Chen, Zhen, Rice, Megan S., Amin, Nikhil, Ardeleanu, Marius, Radin, Allen, Shumel, Brad, Ruddy, Marcella, Patel, Naimish, Pirozzi, Gianluca, Mannent, Leda, Graham, Neil M. H.
Published in Clinical and experimental allergy (01.07.2021)
Published in Clinical and experimental allergy (01.07.2021)
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Journal Article
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis
Hamilton, Jennifer D., PhD, Suárez-Fariñas, Mayte, PhD, Dhingra, Nikhil, BS, Cardinale, Irma, MSc, Li, Xuan, PhD, Kostic, Ana, PhD, Ming, Jeffrey E., MD, PhD, Radin, Allen R., MD, Krueger, James G., MD, Graham, Neil, MD, Yancopoulos, George D., MD, PhD, Pirozzi, Gianluca, MD, PhD, Guttman-Yassky, Emma, MD, PhD
Published in Journal of allergy and clinical immunology (01.12.2014)
Published in Journal of allergy and clinical immunology (01.12.2014)
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Journal Article
Type 2 Inflammation Contributes to Skin Barrier Dysfunction in Atopic Dermatitis
Beck, Lisa A., Cork, Michael J., Amagai, Masayuki, De Benedetto, Anna, Kabashima, Kenji, Hamilton, Jennifer D., Rossi, Ana B.
Published in JID innovations (01.09.2022)
Published in JID innovations (01.09.2022)
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Journal Article
Casirivimab + imdevimab accelerates symptom resolution linked to improved COVID-19 outcomes across susceptible antibody and risk profiles
Li, Dateng, Xu, Meng, Hooper, Andrea T., Rofail, Diana, Mohammadi, Kusha A., Chen, Yiziying, Ali, Shazia, Norton, Thomas, Weinreich, David M., Musser, Bret J., Hamilton, Jennifer D., Geba, Gregory P.
Published in Scientific reports (07.08.2023)
Published in Scientific reports (07.08.2023)
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Repeat subcutaneous administration of casirivimab and imdevimab in adults is well-tolerated and prevents the occurrence of COVID-19
Isa, Flonza, Forleo-Neto, Eduardo, Meyer, Jonathan, Zheng, Wenjun, Rasmussen, Scott, Armas, Danielle, Oshita, Masaru, Brinson, Cynthia, Folkerth, Steven, Faria, Lori, Heirman, Ingeborg, Sarkar, Neena, Musser, Bret J., Bansal, Shikha, O'Brien, Meagan P., Turner, Kenneth C., Ganguly, Samit, Mahmood, Adnan, Dupljak, Ajla, Hooper, Andrea T., Hamilton, Jennifer D., Kim, Yunji, Kowal, Bari, Soo, Yuhwen, Geba, Gregory P., Lipsich, Leah, Braunstein, Ned, Yancopoulos, George D., Weinreich, David M., Herman, Gary A.
Published in International journal of infectious diseases (01.09.2022)
Published in International journal of infectious diseases (01.09.2022)
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Casirivimab and Imdevimab Treatment Reduces Viral Load and Improves Clinical Outcomes in Seropositive Hospitalized COVID-19 Patients with Nonneutralizing or Borderline Neutralizing Antibodies
Hooper, Andrea T, Somersan-Karakaya, Selin, McCarthy, Shane E, Mylonakis, Eleftherios, Ali, Shazia, Mei, Jingning, Bhore, Rafia, Mahmood, Adnan, Geba, Gregory P, Dakin, Paula, Weinreich, David M, Yancopoulos, George D, Herman, Gary A, Hamilton, Jennifer D
Published in mBio (20.12.2022)
Published in mBio (20.12.2022)
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Journal Article
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Dupilumab in Healthy Adult Subjects
Li, Zhaoyang, Radin, Allen, Li, Meng, Hamilton, Jennifer D., Kajiwara, Miyuki, Davis, John D., Takahashi, Yoshinori, Hasegawa, Setsuo, Ming, Jeffrey E., DiCioccio, A. Thomas, Li, Yongtao, Kovalenko, Pavel, Lu, Qiang, Ortemann‐Renon, Catherine, Ardeleanu, Marius, Swanson, Brian N.
Published in Clinical pharmacology in drug development (01.08.2020)
Published in Clinical pharmacology in drug development (01.08.2020)
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Digital wearable insole-based identification of knee arthropathies and gait signatures using machine learning
Wipperman, Matthew F, Lin, Allen Z, Gayvert, Kaitlyn M, Lahner, Benjamin, Somersan-Karakaya, Selin, Wu, Xuefang, Im, Joseph, Lee, Minji, Koyani, Bharatkumar, Setliff, Ian, Thakur, Malika, Duan, Daoyu, Breazna, Aurora, Wang, Fang, Lim, Wei Keat, Halasz, Gabor, Urbanek, Jacek, Patel, Yamini, Atwal, Gurinder S, Hamilton, Jennifer D, Stuart, Samuel, Levy, Oren, Avbersek, Andreja, Alaj, Rinol, Hamon, Sara C, Harari, Olivier
Published in eLife (30.04.2024)
Published in eLife (30.04.2024)
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Assessing the safety and pharmacokinetics of casirivimab and imdevimab (CAS+IMD) in a cohort of pregnant outpatients with COVID-19: results from an adaptive, multicentre, randomised, double-blind, phase 1/2/3 study
Norton, Thomas D, Thakur, Mazhar, Ganguly, Samit, Ali, Shazia, Chao, Jesse, Waldron, Alpana, Xiao, Jing, Patel, Yogesh, Turner, Kenneth C, Davis, John D, Irvin, Susan C, Pan, Cynthia, Atmodjo-Watkins, Dominique, Hooper, Andrea T, Hamilton, Jennifer D, Subramaniam, Danise, Bocchini, Joseph A, Kowal, Bari, DiCioccio, A. Thomas, Bhore, Rafia, Geba, Gregory P, Cox, Edward, Braunstein, Ned, Dakin, Paula, Herman, Gary A
Published in BMJ open (08.10.2024)
Published in BMJ open (08.10.2024)
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Journal Article
Modular Analysis of Peripheral Blood Gene Expression in Rheumatoid Arthritis Captures Reproducible Gene Expression Changes in Tumor Necrosis Factor Responders
Oswald, Michaela, Curran, Mark E., Lamberth, Sarah L., Townsend, Robert M., Hamilton, Jennifer D., Chernoff, David N., Carulli, John, Townsend, Michael J., Weinblatt, Michael E., Kern, Marlena, Pond, Cassandra M., Lee, Annette, Gregersen, Peter K.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2015)
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Journal Article
Dupilumab Suppresses Fractional Exhaled Nitric Oxide (FeNO) and Biomarkers of Type 2 Inflammation in Adult Patients with Persistent Uncontrolled Asthma Despite Use of Medium-to-High Dose Inhaled Corticosteroids Plus Long-Acting Beta-Agonists (ICS/LABAs)
Swanson, Brian N., PhD, Teper, Ariel, MD, Hamilton, Jennifer D., PhD, Zhang, Bingzhi, PhD, Staudinger, Heribert, MD, Tian, Nian, Wang, Ying, PhD, Ming, Jeffrey E., MD, PhD, Graham, Neil M.H., MD, Pirozzi, Gianluca, MD, PhD
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
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Journal Article
Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis
Dellon, Evan S., Rothenberg, Marc E., Collins, Margaret H., Hirano, Ikuo, Chehade, Mirna, Bredenoord, Albert J., Lucendo, Alfredo J., Spergel, Jonathan M., Aceves, Seema, Sun, Xian, Kosloski, Matthew P., Kamal, Mohamed A., Hamilton, Jennifer D., Beazley, Bethany, McCann, Eilish, Patel, Kiran, Mannent, Leda P., Laws, Elizabeth, Akinlade, Bolanle, Amin, Nikhil, Lim, Wei Keat, Wipperman, Matthew F., Ruddy, Marcella, Patel, Naimish, Weinreich, David R., Yancopoulos, George D., Shumel, Brad, Maloney, Jennifer, Giannelou, Angeliki, Shabbir, Arsalan
Published in The New England journal of medicine (22.12.2022)
Published in The New England journal of medicine (22.12.2022)
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Journal Article
Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis
Hirano, Ikuo, Dellon, Evan S., Hamilton, Jennifer D., Collins, Margaret H., Peterson, Kathryn, Chehade, Mirna, Schoepfer, Alain M., Safroneeva, Ekaterina, Rothenberg, Marc E., Falk, Gary W., Assouline-Dayan, Yehudith, Zhao, Qiong, Chen, Zhen, Swanson, Brian N., Pirozzi, Gianluca, Mannent, Leda, Graham, Neil M.H., Akinlade, Bolanle, Stahl, Neil, Yancopoulos, George D., Radin, Allen
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2020)
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Journal Article
IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis
Callewaert, Chris, Nakatsuji, Teruaki, Knight, Rob, Kosciolek, Tomasz, Vrbanac, Alison, Kotol, Paul, Ardeleanu, Marius, Hultsch, Thomas, Guttman-Yassky, Emma, Bissonnette, Robert, Silverberg, Jonathan I., Krueger, James, Menter, Alan, Graham, Neil M.H., Pirozzi, Gianluca, Hamilton, Jennifer D., Gallo, Richard L.
Published in Journal of investigative dermatology (01.01.2020)
Published in Journal of investigative dermatology (01.01.2020)
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Journal Article
Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis: A Phase 3 Randomized Clinical Trial
Simpson, Eric L, Paller, Amy S, Siegfried, Elaine C, Boguniewicz, Mark, Sher, Lawrence, Gooderham, Melinda J, Beck, Lisa A, Guttman-Yassky, Emma, Pariser, David, Blauvelt, Andrew, Weisman, Jamie, Lockshin, Benjamin, Hultsch, Thomas, Zhang, Qin, Kamal, Mohamed A, Davis, John D, Akinlade, Bolanle, Staudinger, Heribert, Hamilton, Jennifer D, Graham, Neil M H, Pirozzi, Gianluca, Gadkari, Abhijit, Eckert, Laurent, Stahl, Neil, Yancopoulos, George D, Ruddy, Marcella, Bansal, Ashish
Published in JAMA dermatology (Chicago, Ill.) (01.01.2020)
Published in JAMA dermatology (Chicago, Ill.) (01.01.2020)
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REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19
Weinreich, David M, Sivapalasingam, Sumathi, Norton, Thomas, Ali, Shazia, Gao, Haitao, Bhore, Rafia, Musser, Bret J, Soo, Yuhwen, Rofail, Diana, Im, Joseph, Perry, Christina, Pan, Cynthia, Hosain, Romana, Mahmood, Adnan, Davis, John D, Turner, Kenneth C, Hooper, Andrea T, Hamilton, Jennifer D, Baum, Alina, Kyratsous, Christos A, Kim, Yunji, Cook, Amanda, Kampman, Wendy, Kohli, Anita, Sachdeva, Yessica, Graber, Ximena, Kowal, Bari, DiCioccio, Thomas, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D
Published in New England Journal of Medicine (21.01.2021)
Published in New England Journal of Medicine (21.01.2021)
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