Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides
Gilding, Edward K., Jackson, Mark A., Nguyen, Linh T. T., Hamilton, Brett R., Farquharson, Katherine A., Ho, Wing L., Yap, Kuok, Hogg, Carolyn J., Belov, Katherine, Craik, David J.
Published in Nature communications (03.08.2024)
Published in Nature communications (03.08.2024)
Get full text
Journal Article
Production and packaging of a biological arsenal: Evolution of centipede venoms under morphological constraint
Undheim, Eivind A. B., Hamilton, Brett R., Kurniawan, Nyoman D., Bowlay, Greg, Cribb, Bronwen W., Merritt, David J., Fry, Bryan G., King, Glenn F., Venter, Deon J.
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2015)
Get full text
Journal Article
A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa , reveals a hyperdiverse hymenopteran toxin gene family
Robinson, Samuel D, Mueller, Alexander, Clayton, Daniel, Starobova, Hana, Hamilton, Brett R, Payne, Richard J, Vetter, Irina, King, Glenn F, Undheim, Eivind A B
Published in Science advances (01.09.2018)
Published in Science advances (01.09.2018)
Get full text
Journal Article
Physiological constraints dictate toxin spatial heterogeneity in snake venom glands
Kazandjian, Taline D, Hamilton, Brett R, Robinson, Samuel D, Hall, Steven R, Bartlett, Keirah E, Rowley, Paul, Wilkinson, Mark C, Casewell, Nicholas R, Undheim, Eivind A. B
Published in BMC biology (27.06.2022)
Published in BMC biology (27.06.2022)
Get full text
Journal Article
Spatial Distribution and Biochemical Characterization of Serine Peptidase Inhibitors in the Venom of the Brazilian Sea Anemone Anthopleura cascaia Using Mass Spectrometry Imaging
da Silva, Daiane Laise, Valladão, Rodrigo, Beraldo-Neto, Emidio, Coelho, Guilherme Rabelo, Neto, Oscar Bento da Silva, Vigerelli, Hugo, Lopes, Adriana Rios, Hamilton, Brett R., Undheim, Eivind A. B., Sciani, Juliana Mozer, Pimenta, Daniel Carvalho
Published in Marine drugs (30.08.2023)
Published in Marine drugs (30.08.2023)
Get full text
Journal Article
Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family
Ashwood, Lauren M, Elnahriry, Khaled A, Stewart, Zachary K, Shafee, Thomas, Naseem, Muhammad Umair, Szanto, Tibor G, van der Burg, Chloé A, Smith, Hayden L, Surm, Joachim M, Undheim, Eivind A B, Madio, Bruno, Hamilton, Brett R, Guo, Shaodong, Wai, Dorothy C C, Coyne, Victoria L, Phillips, Matthew J, Dudley, Kevin J, Hurwood, David A, Panyi, Gyorgy, King, Glenn F, Pavasovic, Ana, Norton, Raymond S, Prentis, Peter J
Published in BMC biology (24.05.2023)
Published in BMC biology (24.05.2023)
Get full text
Journal Article
Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation
Jia, Xinying, Chin, Yanni K.-Y., Zhang, Alan H., Crawford, Theo, Zhu, Yifei, Fletcher, Nicholas L., Zhou, Zihan, Hamilton, Brett R., Stroet, Martin, Thurecht, Kristofer J., Mobli, Mehdi
Published in Communications chemistry (04.03.2023)
Published in Communications chemistry (04.03.2023)
Get full text
Journal Article
Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways
Zheng, Xiaofeng, Linke, Sarah, Dias, José M, Zheng, Xiaowei, Gradin, Katarina, Wallis, Tristan P, Hamilton, Brett R, Gustafsson, Maria, Ruas, Jorge L, Wilkins, Sarah, Bilton, Rebecca L, Brismar, Kerstin, Whitelaw, Murray L, Pereira, Teresa, Gorman, Jeffrey J, Ericson, Johan, Peet, Daniel J, Lendahl, Urban, Poellinger, Lorenz
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.2008)
Get full text
Journal Article
Spatial analysis of the osteoarthritis microenvironment: techniques, insights, and applications
Fan, Xiwei, Sun, Antonia Rujia, Young, Reuben S. E., Afara, Isaac O., Hamilton, Brett R., Ong, Louis Jun Ye, Crawford, Ross, Prasadam, Indira
Published in Bone Research (04.02.2024)
Published in Bone Research (04.02.2024)
Get full text
Journal Article
Venoms for all occasions: The functional toxin profiles of different anatomical regions in sea anemones are related to their ecological function
Ashwood, Lauren M., Undheim, Eivind A. B., Madio, Bruno, Hamilton, Brett R., Daly, Marymegan, Hurwood, David A., King, Glenn F., Prentis, Peter J.
Published in Molecular ecology (01.02.2022)
Published in Molecular ecology (01.02.2022)
Get full text
Journal Article
A process of convergent amplification and tissue‐specific expression dominates the evolution of toxin and toxin‐like genes in sea anemones
Surm, Joachim M., Smith, Hayden L., Madio, Bruno, Undheim, Eivind A.B., King, Glenn F., Hamilton, Brett R., Burg, Chloé A., Pavasovic, Ana, Prentis, Peter J.
Published in Molecular ecology (01.05.2019)
Published in Molecular ecology (01.05.2019)
Get full text
Journal Article
Evolution, Expression Patterns, and Distribution of Novel Ribbon Worm Predatory and Defensive Toxins
Verdes, Aida, Taboada, Sergi, Hamilton, Brett R., Undheim, Eivind A.B., Sonoda, Gabriel G., Andrade, Sonia C.S., Morato, Esperanza, Marina, Ana Isabel, Cárdenas, César A., Riesgo, Ana
Published in Molecular biology and evolution (03.05.2022)
Published in Molecular biology and evolution (03.05.2022)
Get full text
Journal Article
Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox
Xie, Jing, Robinson, Samuel D., Gilding, Edward K., Jami, Sina, Deuis, Jennifer R., Rehm, Fabian B.H., Yap, Kuok, Ragnarsson, Lotten, Chan, Lai Yue, Hamilton, Brett R., Harvey, Peta J., Craik, David J., Vetter, Irina, Durek, Thomas
Published in The Journal of biological chemistry (01.08.2022)
Published in The Journal of biological chemistry (01.08.2022)
Get full text
Journal Article
Cryo-ultramicrotomy and Mass Spectrometry Imaging Analysis of Nudibranch Microstructures
Hamilton, Brett R, Chan, Weili, Cheney, Karen L, Sullivan, Robert K. P, Floetenmeyer, Matthias, Garson, Mary J, Wepf, Roger
Published in Journal of the American Society for Mass Spectrometry (02.03.2022)
Published in Journal of the American Society for Mass Spectrometry (02.03.2022)
Get full text
Journal Article
PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold
Madio, Bruno, Peigneur, Steve, Chin, Yanni K. Y., Hamilton, Brett R., Henriques, Sónia Troeira, Smith, Jennifer J., Cristofori-Armstrong, Ben, Dekan, Zoltan, Boughton, Berin A., Alewood, Paul F., Tytgat, Jan, King, Glenn F., Undheim, Eivind A. B.
Published in Cellular and molecular life sciences : CMLS (01.12.2018)
Published in Cellular and molecular life sciences : CMLS (01.12.2018)
Get full text
Journal Article
Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid α/β‑Hydrolase Domain 6 (ABHD6)
Mardon, Karine, Patel, Jayendra Z., Savinainen, Juha R., Stimson, Damion H. R., Oyagawa, Caitlin R. M., Grimsey, Natasha L., Migotto, Mary-anne, Njiru, Grace F. M., Hamilton, Brett R., Cowin, Gary, Yli-Kauhaluoma, Jari, Vanduffel, Wim, Blakey, Idriss, Bhalla, Rajiv, Cawthorne, Christopher, Celen, Sofie, Bormans, Guy, Thurecht, Kristofer J, Ahamed, Muneer
Published in Journal of medicinal chemistry (12.01.2023)
Published in Journal of medicinal chemistry (12.01.2023)
Get full text
Journal Article
Functional mass spectrometry imaging maps phospholipase-A2 enzyme activity during osteoarthritis progression
Fan, Xiwei, Young, Reuben S. E., Sun, Antonia Rujia, Hamilton, Brett R., Nedunchezhiyan, Udhaya, Crawford, Ross, Blanksby, Stephen J., Prasadam, Indira
Published in Theranostics (01.01.2023)
Published in Theranostics (01.01.2023)
Get full text
Journal Article
Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial
Burr, Lucy D, Rogers, Geraint B, Chen, Alice C-H, Hamilton, Brett R, Pool, Gertruida F, Taylor, Steven L, Venter, Deon, Bowler, Simon D, Biga, Sally, McGuckin, Michael A
Published in Annals of the American Thoracic Society (01.10.2016)
Published in Annals of the American Thoracic Society (01.10.2016)
Get full text
Journal Article
Multifunctional warheads: Diversification of the toxin arsenal of centipedes via novel multidomain transcripts
Undheim, Eivind A.B., Sunagar, Kartik, Hamilton, Brett R., Jones, Alun, Venter, Deon J., Fry, Bryan G., King, Glenn F.
Published in Journal of proteomics (06.05.2014)
Published in Journal of proteomics (06.05.2014)
Get full text
Journal Article