Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a
Lohman, Rink-Jan, Hamidon, Johan K, Reid, Robert C, Rowley, Jessica A, Yau, Mei-Kwan, Halili, Maria A, Nielsen, Daniel S, Lim, Junxian, Wu, Kai-Chen, Loh, Zhixuan, Do, Anh, Suen, Jacky Y, Iyer, Abishek, Fairlie, David P
Published in Nature communications (24.08.2017)
Published in Nature communications (24.08.2017)
Get full text
Journal Article
Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity
Rowley, Jessica A, Reid, Robert C, Poon, Eunice K. Y, Wu, Kai-Chen, Lim, Junxian, Lohman, Rink-Jan, Hamidon, Johan K, Yau, Mei-Kwan, Halili, Maria A, Durek, Thomas, Iyer, Abishek, Fairlie, David P
Published in Journal of medicinal chemistry (23.01.2020)
Published in Journal of medicinal chemistry (23.01.2020)
Get full text
Journal Article
Potent Heterocyclic Ligands for Human Complement C3a Receptor
Reid, Robert C, Yau, Mei-Kwan, Singh, Ranee, Hamidon, Johan K, Lim, Junxian, Stoermer, Martin J, Fairlie, David P
Published in Journal of medicinal chemistry (23.10.2014)
Published in Journal of medicinal chemistry (23.10.2014)
Get full text
Journal Article
Downsizing a human inflammatory protein to a small molecule with equal potency and functionality
Reid, Robert C, Yau, Mei-Kwan, Singh, Ranee, Hamidon, Johan K, Reed, Anthony N, Chu, Peifei, Suen, Jacky Y, Stoermer, Martin J, Blakeney, Jade S, Lim, Junxian, Faber, Jonathan M, Fairlie, David P
Published in Nature communications (2013)
Published in Nature communications (2013)
Get full text
Journal Article