Polygenic basis and biomedical consequences of telomere length variation
Codd, Veryan, Wang, Qingning, Allara, Elias, Musicha, Crispin, Kaptoge, Stephen, Stoma, Svetlana, Jiang, Tao, Hamby, Stephen E., Braund, Peter S., Bountziouka, Vasiliki, Budgeon, Charley A., Denniff, Matthew, Swinfield, Chloe, Papakonstantinou, Manolo, Sheth, Shilpi, Nanus, Dominika E., Warner, Sophie C., Wang, Minxian, Khera, Amit V., Eales, James, Ouwehand, Willem H., Thompson, John R., Di Angelantonio, Emanuele, Wood, Angela M., Butterworth, Adam S., Danesh, John N., Nelson, Christopher P., Samani, Nilesh J.
Published in Nature genetics (01.10.2021)
Published in Nature genetics (01.10.2021)
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Comparative analysis of genome sequences covering the seven cronobacter species
Joseph, Susan, Desai, Prerak, Ji, Yongmei, Cummings, Craig A, Shih, Rita, Degoricija, Lovorka, Rico, Alain, Brzoska, Pius, Hamby, Stephen E, Masood, Naqash, Hariri, Sumyya, Sonbol, Hana, Chuzhanova, Nadia, McClelland, Michael, Furtado, Manohar R, Forsythe, Stephen J
Published in PloS one (16.11.2012)
Published in PloS one (16.11.2012)
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Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation
Adlam, David, Berrandou, Takiy-Eddine, Georges, Adrien, Nelson, Christopher P., Giannoulatou, Eleni, Henry, Joséphine, Ma, Lijiang, Blencowe, Montgomery, Turley, Tamiel N., Yang, Min-Lee, Chopade, Sandesh, Finan, Chris, Braund, Peter S., Sadeg-Sayoud, Ines, Iismaa, Siiri E., Kosel, Matthew L., Zhou, Xiang, Hamby, Stephen E., Cheng, Jenny, Liu, Lu, Tarr, Ingrid, Muller, David W. M., d’Escamard, Valentina, King, Annette, Brunham, Liam R., Baranowska-Clarke, Ania A., Debette, Stéphanie, Amouyel, Philippe, Olin, Jeffrey W., Patil, Snehal, Hesselson, Stephanie E., Junday, Keerat, Kanoni, Stavroula, Aragam, Krishna G., Butterworth, Adam S., Tweet, Marysia S., Gulati, Rajiv, Combaret, Nicolas, Kadian-Dodov, Daniella, Kalman, Jonathan M., Fatkin, Diane, Hingorani, Aroon D., Saw, Jacqueline, Webb, Tom R., Hayes, Sharonne N., Yang, Xia, Ganesh, Santhi K., Olson, Timothy M., Kovacic, Jason C., Graham, Robert M., Samani, Nilesh J., Bouatia-Naji, Nabila
Published in Nature genetics (01.06.2023)
Published in Nature genetics (01.06.2023)
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Adult height and risk of 50 diseases: a combined epidemiological and genetic analysis
Lai, Florence Y, Nath, Mintu, Hamby, Stephen E, Thompson, John R, Nelson, Christopher P, Samani, Nilesh J
Published in BMC medicine (25.10.2018)
Published in BMC medicine (25.10.2018)
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Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia
Georges, Adrien, Albuisson, Juliette, Berrandou, Takiy, Dupré, Délia, Lorthioir, Aurélien, D’Escamard, Valentina, Di Narzo, Antonio F, Kadian-Dodov, Daniella, Olin, Jeffrey W, Warchol-Celinska, Ewa, Prejbisz, Aleksander, Januszewicz, Andrzej, Bruneval, Patrick, Baranowska, Anna A, Webb, Tom R, Hamby, Stephen E, Samani, Nilesh J, Adlam, David, Fendrikova-Mahlay, Natalia, Hazen, Stanley, Wang, Yu, Yang, Min-Lee, Hunker, Kristina, Combaret, Nicolas, Motreff, Pascal, Chédid, Antoine, Fiquet, Béatrice, Plouin, Pierre-François, Mousseaux, Elie, Azarine, Arshid, Amar, Laurence, Azizi, Michel, Gornik, Heather L, Ganesh, Santhi K, Kovacic, Jason C, Jeunemaitre, Xavier, Bouatia-Naji, Nabila
Published in Cardiovascular research (01.04.2021)
Published in Cardiovascular research (01.04.2021)
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Contribution of NOTCH1 genetic variants to bicuspid aortic valve and other congenital lesions
Debiec, Radoslaw Marek, Hamby, Stephen E, Jones, Peter D, Safwan, Kassem, Sosin, Michael, Hetherington, Simon Lee, Sprigings, David, Sharman, David, Lee, Kelvin, Salahshouri, Pegah, Wheeldon, Nigel, Chukwuemeka, Andrew, Boutziouka, Vasiliki, Elamin, Mohamed, Coolman, Sue, Asiani, Manish, Kharodia, Shireen, Skinner, Gregory J, Samani, Nilesh J, Webb, Tom R, Bolger, Aidan P
Published in Heart (British Cardiac Society) (01.07.2022)
Published in Heart (British Cardiac Society) (01.07.2022)
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Prediction of Causal Candidate Genes in Coronary Artery Disease Loci
Brænne, Ingrid, Civelek, Mete, Vilne, Baiba, Di Narzo, Antonio, Johnson, Andrew D, Zhao, Yuqi, Reiz, Benedikt, Codoni, Veronica, Webb, Thomas R, Foroughi Asl, Hassan, Hamby, Stephen E, Zeng, Lingyao, Trégouët, David-Alexandre, Hao, Ke, Topol, Eric J, Schadt, Eric E, Yang, Xia, Samani, Nilesh J, Björkegren, Johan L M, Erdmann, Jeanette, Schunkert, Heribert, Lusis, Aldons J
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2015)
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Aging-related defects in macrophage function are driven by MYC and USF1 transcriptional programs
Moss, Charlotte E., Johnston, Simon A., Kimble, Joshua V., Clements, Martha, Codd, Veryan, Hamby, Stephen, Goodall, Alison H., Deshmukh, Sumeet, Sudbery, Ian, Coca, Daniel, Wilson, Heather L., Kiss-Toth, Endre
Published in Cell reports (Cambridge) (23.04.2024)
Published in Cell reports (Cambridge) (23.04.2024)
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Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets
Lempiäinen, Harri, Brænne, Ingrid, Michoel, Tom, Tragante, Vinicius, Vilne, Baiba, Webb, Tom R., Kyriakou, Theodosios, Eichner, Johannes, Zeng, Lingyao, Willenborg, Christina, Franzen, Oscar, Ruusalepp, Arno, Goel, Anuj, van der Laan, Sander W., Biegert, Claudia, Hamby, Stephen, Talukdar, Husain A., Foroughi Asl, Hassan, Pasterkamp, Gerard, Watkins, Hugh, Samani, Nilesh J., Wittenberger, Timo, Erdmann, Jeanette, Schunkert, Heribert, Asselbergs, Folkert W., Björkegren, Johan L. M.
Published in Scientific reports (21.02.2018)
Published in Scientific reports (21.02.2018)
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Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation From Genome Sequencing
Carss, Keren J, Baranowska, Anna A, Armisen, Javier, Webb, Tom R, Hamby, Stephen E, Premawardhana, Diluka, Al-Hussaini, Abtehale, Wood, Alice, Wang, Quanli, Deevi, Sri V V, Vitsios, Dimitrios, Lewis, Samuel H, Kotecha, Deevia, Bouatia-Naji, Nabila, Hesselson, Stephanie, Iismaa, Siiri E, Tarr, Ingrid, McGrath-Cadell, Lucy, Muller, David W, Dunwoodie, Sally L, Fatkin, Diane, Graham, Robert M, Giannoulatou, Eleni, Samani, Nilesh J, Petrovski, Slavé, Haefliger, Carolina, Adlam, David
Published in Circulation. Genomic and precision medicine (01.12.2020)
Published in Circulation. Genomic and precision medicine (01.12.2020)
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Novel loss of function mutation in NOTCH1 in a family with bicuspid aortic valve, ventricular septal defect, thoracic aortic aneurysm, and aortic valve stenosis
Debiec, Radoslaw, Hamby, Stephen E., Jones, Peter D., Coolman, Sue, Asiani, Manish, Kharodia, Shireen, Skinner, Gregory J., Samani, Nilesh J., Webb, Tom R., Bolger, Aidan
Published in Molecular genetics & genomic medicine (01.10.2020)
Published in Molecular genetics & genomic medicine (01.10.2020)
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Exploring the Genetic Architecture of Spontaneous Coronary Artery Dissection Using Whole-Genome Sequencing
Tarr, Ingrid, Hesselson, Stephanie, Iismaa, Siiri E, Rath, Emma, Monger, Steven, Troup, Michael, Mishra, Ketan, Wong, Claire M Y, Hsu, Pei-Chen, Junday, Keerat, Humphreys, David T, Adlam, David, Webb, Tom R, Baranowska-Clarke, Anna A, Hamby, Stephen E, Carss, Keren J, Samani, Nilesh J, Bax, Monique, McGrath-Cadell, Lucy, Kovacic, Jason C, Dunwoodie, Sally L, Fatkin, Diane, Muller, David W M, Graham, Robert M, Giannoulatou, Eleni
Published in Circulation. Genomic and precision medicine (01.08.2022)
Published in Circulation. Genomic and precision medicine (01.08.2022)
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Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion
Johnston, Jessica M, Angyal, Adrienn, Bauer, Robert C, Hamby, Stephen, Suvarna, S Kim, Baidžajevas, Kajus, Hegedus, Zoltan, Dear, T Neil, Turner, Martin, Wilson, Heather L, Goodall, Alison H, Rader, Daniel J, Shoulders, Carol C, Francis, Sheila E, Kiss-Toth, Endre
Published in Science advances (01.10.2019)
Published in Science advances (01.10.2019)
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Tribbles 3 deficiency promotes atherosclerotic fibrous cap thickening and macrophage-mediated extracellular matrix remodelling
Martinez-Campesino, Laura, Kocsy, Klaudia, Cañedo, Jaime, Johnston, Jessica M., Moss, Charlotte E., Johnston, Simon A., Hamby, Stephen, Goodall, Alison H., Redgrave, Jessica, Francis, Sheila E., Kiss-Toth, Endre, Wilson, Heather L.
Published in Frontiers in cardiovascular medicine (26.08.2022)
Published in Frontiers in cardiovascular medicine (26.08.2022)
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Exploring the somatic NF1 mutational spectrum associated with NF1 cutaneous neurofibromas
THOMAS, Laura, SPURLOCK, Gill, UPADHYAYA, Meena, EUDALL, Claire, THOMAS, Nick S, MORT, Matthew, HAMBY, Stephen E, CHUZHANOVA, Nadia, BREMS, Hilde, LEGIUS, Eric, COOPER, David N
Published in European journal of human genetics : EJHG (01.04.2012)
Published in European journal of human genetics : EJHG (01.04.2012)
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Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumor suppressor genes
Ivanov, Dobril, Hamby, Stephen E., Stenson, Peter D., Phillips, Andrew D., Kehrer-Sawatzki, Hildegard, Cooper, David N., Chuzhanova, Nadia
Published in Human mutation (01.06.2011)
Published in Human mutation (01.06.2011)
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