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Chino, Ayaka, Seo, Ryushi, Amano, Yasushi, Namatame, Ichiji, Hamaguchi, Wataru, Honbou, Kazuya, Mihara, Takuma, Yamazaki, Mayako, Tomishima, Masaki, Masuda, Naoyuki
Published in Chemical & pharmaceutical bulletin (2018)
Published in Chemical & pharmaceutical bulletin (2018)
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Atropisomeric 4‑Phenyl‑4H‑1,2,4-triazoles as Selective Glycine Transporter 1 Inhibitors
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Published in Journal of medicinal chemistry (25.07.2013)
Published in Journal of medicinal chemistry (25.07.2013)
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Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436
Hamaguchi, Wataru, Masuda, Naoyuki, Miyamoto, Satoshi, Kikuchi, Shigetoshi, Narazaki, Fumie, Shiina, Yasuhiro, Seo, Ryushi, Amano, Yasushi, Mihara, Takuma, Moriguchi, Hiroyuki, Hattori, Kouji
Published in Bioorganic & medicinal chemistry (01.07.2015)
Published in Bioorganic & medicinal chemistry (01.07.2015)
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Potent and orally bioavailable CCR4 antagonists: Synthesis and structure–activity relationship study of 2-aminoquinazolines
Yokoyama, Kazuhiro, Ishikawa, Noriko, Igarashi, Susumu, Kawano, Noriyuki, Masuda, Naoyuki, Hamaguchi, Wataru, Yamasaki, Shingo, Koganemaru, Yohei, Hattori, Kazuyuki, Miyazaki, Takahiro, Ogino, Shin-ichi, Matsumoto, Yuzo, Takeuchi, Makoto, Ohta, Mitsuaki
Published in Bioorganic & medicinal chemistry (2009)
Published in Bioorganic & medicinal chemistry (2009)
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Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors
Chino, Ayaka, Honda, Shugo, Morita, Masataka, Yonezawa, Koichi, Hamaguchi, Wataru, Amano, Yasushi, Moriguchi, Hiroyuki, Yamazaki, Mayako, Aota, Masaki, Tomishima, Masaki, Masuda, Naoyuki
Published in Bioorganic & medicinal chemistry (15.08.2019)
Published in Bioorganic & medicinal chemistry (15.08.2019)
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Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition
Hamaguchi, Wataru, Masuda, Naoyuki, Isomura, Mai, Miyamoto, Satoshi, Kikuchi, Shigetoshi, Amano, Yasushi, Honbou, Kazuya, Mihara, Takuma, Watanabe, Toshihiro
Published in Bioorganic & medicinal chemistry (15.12.2013)
Published in Bioorganic & medicinal chemistry (15.12.2013)
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Atropisomeric 4-Phenyl-4 H -1,2,4-triazoles as Selective Glycine Transporter 1 Inhibitors
Sugane, Takashi, Tobe, Takahiko, Hamaguchi, Wataru, Shimada, Itsuro, Maeno, Kyoichi, Miyata, Junji, Suzuki, Takeshi, Kimizuka, Tetsuya, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Journal of medicinal chemistry (25.07.2013)
Published in Journal of medicinal chemistry (25.07.2013)
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Synthesis, SAR study, and biological evaluation of novel quinoline derivatives as phosphodiesterase 10A inhibitors with reduced CYP3A4 inhibition
Hamaguchi, Wataru, Masuda, Naoyuki, Miyamoto, Satoshi, Shiina, Yasuhiro, Kikuchi, Shigetoshi, Mihara, Takuma, Moriguchi, Hiroyuki, Fushiki, Hiroshi, Murakami, Yoshihiro, Amano, Yasushi, Honbou, Kazuya, Hattori, Kouji
Published in Bioorganic & medicinal chemistry (15.01.2015)
Published in Bioorganic & medicinal chemistry (15.01.2015)
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Journal Article
Fragment-Based Discovery of Pyrimido[1,2-b]indazole PDE10A Inhibitors
Ayaka Chino, Ryushi Seo, Yasushi Amano, Ichiji Namatame, Wataru Hamaguchi, Kazuya Honbou, Takuma Mihara, Mayako Yamazaki, Masaki Tomishima, Naoyuki Masuda
Published in Chemical and Pharmaceutical Bulletin (01.03.2018)
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Published in Chemical and Pharmaceutical Bulletin (01.03.2018)
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Synthesis and Biological Evaluation of 3-Biphenyl-4-yl-4-phenyl-4 H -1,2,4-triazoles as Novel Glycine Transporter 1 Inhibitors
Sugane, Takashi, Tobe, Takahiko, Hamaguchi, Wataru, Shimada, Itsuro, Maeno, Kyoichi, Miyata, Junji, Suzuki, Takeshi, Kimizuka, Tetsuya, Kohara, Atsuyuki, Morita, Takuma, Doihara, Hitoshi, Saita, Kyouko, Aota, Masaki, Furutani, Masako, Shimada, Yoshiaki, Hamada, Noritaka, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
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Discovery and biological evaluation of novel 4-amino-2-phenylpyrimidine derivatives as potent and orally active GPR119 agonists
Negoro, Kenji, Yonetoku, Yasuhiro, Misawa-Mukai, Hana, Hamaguchi, Wataru, Maruyama, Tatsuya, Yoshida, Shigeru, Takeuchi, Makoto, Ohta, Mitsuaki
Published in Bioorganic & medicinal chemistry (01.09.2012)
Published in Bioorganic & medicinal chemistry (01.09.2012)
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Synthesis and Biological Evaluation of 3-Biphenyl-4-yl-4-phenyl-4H-1,2,4-triazoles as Novel Glycine Transporter 1 Inhibitors
Sugane, Takashi, Tobe, Takahiko, Hamaguchi, Wataru, Shimada, Itsuro, Maeno, Kyoichi, Miyata, Junji, Suzuki, Takeshi, Kimizuka, Tetsuya, Kohara, Atsuyuki, Morita, Takuma, Doihara, Hitoshi, Saita, Kyouko, Aota, Masaki, Furutani, Masako, Shimada, Yoshiaki, Hamada, Noritaka, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
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Practical and efficient synthesis of the (R)-atropisomer of a 4-phenyl 1,2,4-triazole derivative as a selective GlyT1 inhibitor
Sugane, Takashi, Hamada, Noritaka, Tobe, Takahiko, Hamaguchi, Wataru, Shimada, Itsuro, Maeno, Kyoichi, Miyata, Junji, Suzuki, Takeshi, Kimizuka, Tetsuya, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Tetrahedron: asymmetry (15.12.2012)
Published in Tetrahedron: asymmetry (15.12.2012)
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Synthesis and biological evaluation of (4H-1,2,4-triazol-4-yl)isoquinoline derivatives as selective glycine transporter 1 inhibitors
Sugane, Takashi, Tobe, Takahiko, Hamaguchi, Wataru, Shimada, Itsuro, Maeno, Kyoichi, Miyata, Junji, Suzuki, Takeshi, Kimizuka, Tetsuya, Morita, Takuma, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Bioorganic & medicinal chemistry (01.01.2012)
Published in Bioorganic & medicinal chemistry (01.01.2012)
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SULFUR-CONTAINING BICYCLIC COMPOUND
HONJO ERIKO, TAKUWA TOMOFUMI, KONDO YUJI, HAMAGUCHI WATARU, HOSHII HIROAKI, GOTO TAKAYUKI, SHIRAISHI NOBUYUKI
Year of Publication 21.06.2016
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Year of Publication 21.06.2016
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SULFUR-CONTAINING BICYCLIC COMPOUND
HONJO, ERIKO, GOTO, TAKAYUKI, TAKUWA, TOMOFUMI, HAMAGUCHI, WATARU, SHIRAISHI, NOBUYUKI, HOSHII, HIROAKI, KONDO, YUJI
Year of Publication 23.04.2015
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Year of Publication 23.04.2015
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